Protein Alignment bgcn and rha-2

DIOPT Version :9

• Sequence 1: NP_523832.2
• Gene: bgcn / 47873
• FlyBaseID: FBgn0004581
• Length: 1215
• Species: Drosophila melanogaster
• Sequence 2: NP_498895.1
• Gene: rha-2 / 176207
• WormBaseID: WBGene00015525
• Length: 1148
• Species: Caenorhabditis elegans
• Alignment Length: 1028
• Identity: 187/1028 - (18%)
• Similarity: 352/1028 - (34%)
• Gaps: 278/1028 - (27%)

  Fly    90 TLLSRKSLMGKEDLELYADLVSMKANASDLPSLHLPLPAIRPPNLRFWTEAQLNFLTAFLGHSLS 154
            |:::||.::.:...|:       :.:.::||        |....:|.......|.:|...|.:.|
 Worm   214 TVINRKKVIVERSKEI-------QKSRAELP--------IFAEEMRIVEAINENLVTVVCGETGS 263

  Fly   155 ---DEILQSLYASRVIVYNAALCWDKSVFLPLVILDDCRNKKSNVKIMCI-ERQAILATYNSQRT 215
               .:|.|.||.:                          ...|..:::.| |.:.:.|...:||.
 Worm   264 GKTTQIPQFLYEA--------------------------GYASEGELIGITEPRRVAAIAMAQRV 302

  Fly   216 ANFFGEQLG--ETVGIQLPYFSAVSSSTFIIYSTAQYFLRSLTSQ-QFRNISHLVVNDVHLHDPY 277
                |.:|.  :.|..|:.|....|.:|.|::.|....::.:... ..:..|.:::::.|....|
 Worm   303 ----GVELAKPDEVSYQIRYEGTRSETTNILFMTDGVLMKEMEQDVMLKKYSVILIDEAHERSMY 363

  Fly   278 TDILLSE----IRMALSSHQNLRVVLLSQMGNPKKFTDFFGEGLQLNMIKQPEVAPRVSYLNELH 338
            :|:|:..    :.:...:.:.||:|::|.   ..:..||..:.|      .|.:.|:|..::...
 Worm   364 SDVLIGMLSRIVPLRSKTARPLRLVIMSA---TLRLDDFTHKKL------FPLLTPKVIKVDARQ 419

  Fly   339 SCIALAGIHKGPDIYKEIPEAFRANNPRNEQMDKCLQAYGELGTDAALRPFL---YAVNYDLA-- 398
            ..:::....:.||.|  |..|||.....:|.:           ...|:..|:   :.|...:.
 Worm   420 FPVSVHFEKRTPDDY--IASAFRKTCRIHETL-----------PPGAILVFVTGQHEVKQLITKL 471

  Fly   399 ----PVNYRHSLTGKTAVHFASE-----LNKANHLRLLLFMGADPYIVDLFQQNAISLAAMNGNH 454
                ||.|.....|:..|....|     :..|..::|..|....|...| |:.  :....|:|
 Worm   472 KKRYPVVYETDKNGEVLVKGTKEWKEKKVEAAKSIKLEDFKEETPETED-FED--VDDGLMDG-- 531

  Fly   455 ECIDVLNSYSLHGYVVKSAKPDFVDYDLIIDIMYLLRTKPEYSPGEYSPGNI------------- 506
               |.:|.        :.|...|.||:           :.|...|:.|.|.:
 Worm   532 ---DDMNE--------RGAAEAFDDYE-----------EFENGDGDLSDGKVENSIGAPPADCEP 574

  Fly   507 LIILPTYYHIVKLNYMILSHCLTGSLQECSIFLLYDNMRNDYLQALVNASDETVK----VVLATD 567
            |..||.|             .|....::..:|                  |||..    .|::|:
 Worm   575 LYCLPLY-------------SLLSMGKQRRVF------------------DETPAGMRLCVISTN 608

  Fly   568 IIESLCLKVP-FKYQIDTACRLNNVYDTTSCSGDDRFEWVAKDALLRRELILQPNKGDVQ----- 626
            :.|: .|.:| .||.||.......:||  |.:|..||      |:.|    :....||.:
 Worm   609 VAET-SLTIPGVKYVIDGGFEKRRLYD--SITGVSRF------AVCR----ISQASGDQRAGRAG 660

  Fly   627 ------CFRLISKEAYEELSETSQPSLQTMQLDKICLAVKLLSPNTIISEYLGITISPPPLINVH 685
                  .:||.|...|::..:.:.|.:.:...|::.|.:|.::...:::....   |.|....:.
 Worm   661 RISAGHAYRLYSSAVYQDFVKFADPEILSKPADQLVLHLKSMNIVKVVNFPFP---SAPDEQMLE 722

  Fly   686 HAVQFLKKIDVLDDAED-------VTWLGCRLMDIPVSCQLGRMLIFGILLRCLDPILTIVSSLS 743
            .|.:.|.::..|.::..       :|.||..|...|::....:.:........:...:.::|.||
 Worm   723 SAEKRLCRLGALSESTKNGKTEARITKLGKTLAVFPLAPSYAKFIAMADQHNLMSHAILLISLLS 787

  Fly   744 TADPLGIPFTEDIDNLWDRFTIYIQNSIKKERTYLSDNQFSDHFIFVRLYKEWQNRMHNRTPPLY 808
            ..:|| ||.:....:..:.....::|.:|:.|.:.|...       .|...:.:..||..:
 Worm   788 VREPL-IPVSSLRGDTPEETKELMKNVLKERRRWCSHTG-------ARRLGDLKVLMHAAS---- 840

  Fly   809 LKDEYEFMLNGLMEQLTSIRSEIVS-SLRAANLIHSRGKL--SMNNLNQMSCNWHMVKAALTGGM 870
                       :.||:.....|... .||...|:.:| ||  .:.|:...||..... |||...:
 Worm   841 -----------VAEQIKYNARECEKVGLRVKALVEAR-KLRQQLTNIVNASCKKEHA-AALDSDL 892

  Fly   871 YPNIYAVDTRKSSLK----SAFSGNV------SMHPNTVLRDFLEPLNISAQSFRTPW-IVCNRQ 924
            .|   ..|.:...|:    ::||..:      |:....|.:...|...|....|..|. :|...:
 Worm   893 PP---PTDQQAQLLRQMVVASFSDRLARRVDRSVGQEEVQKGAYETTLIKGHVFIDPCSVVFTEE 954

  Fly   925 KSHIVYATLV------VPLAVAMFSGHPRIRLS--------------PICDSEMSLTDRNVNVFI 969
            ...::|..||      :..:|.........||:              ||.|....:..:.|.|..
 Worm   955 PEFVIYQELVQVNEKKLMTSVCAVDKEWLSRLAESYCNYGEQDKNQEPIYDPVKDMVVKTVKVTF 1019

  Fly   970 DEWIWMV--MSKATAEMVMRTRYYFFKMYHDLLKHCSELDMWRRDCEPVSQYT 1020
            ....|.:  .:::....:|..||:...:...|:            .|.:.:||
 Worm  1020 GPLNWELPNENRSVPHDIMMYRYFALFLLDGLV------------FEKLKEYT 1060

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bgcn	NP_523832.2	ANK repeat	406..438	CDD:293786	7/36 (19%)
		ANK	407..>460	CDD:238125	12/57 (21%)
		Ank_2	413..>460	CDD:289560	10/51 (20%)
		HrpA	<484..973	CDD:224557	102/558 (18%)
		HA2	694..763	CDD:214852	13/75 (17%)
		OB_NTP_bind	823..945	CDD:285018	30/141 (21%)
rha-2	NP_498895.1	HrpA	218..989	CDD:224557	173/939 (18%)
		DEXDc	254..394	CDD:238005	31/172 (18%)
		P-loop_NTPase	<350..>477	CDD:304359	26/148 (18%)
		HELICc	577..662	CDD:197757	27/128 (21%)
		HA2	730..822	CDD:214852	16/92 (17%)
		OB_NTP_bind	870..990	CDD:285018	24/123 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900