Protein Alignment bgcn and mog-5

DIOPT Version :10

• Sequence 1: NP_523832.2
• Gene: bgcn / 47873
• FlyBaseID: FBgn0004581
• Length: 1215
• Species: Drosophila melanogaster
• Sequence 2: NP_495019.1
• Gene: mog-5 / 173920
• WormBaseID: WBGene00003393
• Length: 1200
• Species: Caenorhabditis elegans
• Alignment Length: 778
• Identity: 154/778 - (19%)
• Similarity: 268/778 - (34%)
• Gaps: 272/778 - (34%)

  Fly   197 KIMCIERQAILATYNSQRTANFFGEQLGETVGIQLPYFSAVSSSTFIIYSTAQYFLRS-LTSQQF 260
            ||.|.:.:.:.|...::|.|..:|.:||..||..:.:....|..|.|.|.|....||. |.....
 Worm   587 KIGCTQPRRVAAMSVAKRVAEEYGCKLGTDVGYTIRFEDCTSQDTIIKYMTDGMLLRECLIDPDL 651

  Fly   261 RNISHLVVNDVHLHDPYTDILLSEIRMALSSHQNLRVVLLSQMGNPKKFTDFFGEG--------- 316
            ...|.:::::.|....:||:|...::.|......|::::.|...:..||:::|.|.
 Worm   652 SGYSLIMLDEAHERTIHTDVLFGLLKAAARKRPELKLIITSATLDSVKFSEYFLEAPIFTIPGRT 716

  Fly   317 --LQLNMIKQPEVAPRVSYLNELHSCIALAGIHKGPDIYKEIPEAFRANNPRNEQMDKCLQAYGE 379
              :::...::||    ..||...|  |.:..||              ...|
 Worm   717 FPVEILYTREPE----SDYLEAAH--ITVMQIH--------------LTEP-------------- 747

  Fly   380 LGTDAALRPFLYAVNYDLAPVNYRHSLTGKTAVHFASELNKANHLRLLLFMGADPYIVDLFQQNA 444
                               |.:....|||:..:..:.|:                    |:::
 Worm   748 -------------------PGDVLVFLTGQEEIDTSCEV--------------------LYER-- 771

  Fly   445 ISLAAMNGNHECIDVLNSYSLHGYVVKSAKPDFVDYDLIIDIMYLLRTKPEYSPGEYSPGNILII 509
                                     :||..||.                ||           |||
 Worm   772 -------------------------MKSMGPDV----------------PE-----------LII 784

  Fly   510 LPTYYHIVKLNYMILSHCLTGSLQECSIFLLYDNMRNDYLQALVNASDETVKVVLATDIIE-SLC 573
            ||.|                |:|.......::|           .|.....|||:||:|.| ||.
 Worm   785 LPVY----------------GALPSEMQTRIFD-----------PAPAGKRKVVIATNIAETSLT 822

  Fly   574 LKVPFKYQIDTACRLNNVYDTTSCSGDDRFEWVAKDALLRRELILQP--------------NKGD 624
            :...| |.:|.......:|:..  ||.|             .|::.|              ..|.
 Worm   823 IDGIF-YVVDPGFVKQKIYNPK--SGMD-------------SLVVTPISQAAAKQRSGRAGRTGP 871

  Fly   625 VQCFRLISKEAY-EELSETSQPSLQTMQLDKICLAVKLLSPNTIIS-EYLGITISPPPLINVHHA 687
            .:|:||.::.|: :|:..|..|.:|...|....|.:|.:..|.:|. :::    ..|||.::..|
 Worm   872 GKCYRLYTERAFRDEMLPTPVPEIQRTNLASTLLQLKAMGINNLIDFDFM----DAPPLDSMITA 932

  Fly   688 VQFLKKIDVLDDAEDVTWLGCRLMDIPVSCQLGRMLIFGILLRCLDPILTIVSSLSTADPLGIPF 752
            :..|..:..||....:|.||.|:.:.|:...|.::||..:.|.|.:.:||||:.|
 Worm   933 LNTLHTLSALDGDGLLTKLGRRMAEFPLEPSLSKLLIMSVDLGCSEEVLTIVAML---------- 987

  Fly   753 TEDIDNLWDRFTIYIQNSIKKERTYLSDNQFS-------DHFIFVRLYKEWQNRMHNRTPPLYLK 810
              ::.|::.|         .||:...:|.:.:       ||...:.:|..|:|  |:.:.|...:
 Worm   988 --NVQNIFYR---------PKEKQDHADQKKAKFHQPEGDHLTLLAVYNSWKN--HHFSQPWCFE 1039

  Fly   811 DEYEFMLNGLMEQLTSIRSEIVSSLRAANLIHSRGKLSMNNLNQMSCNWHM--VKAALTGGMYPN 873
            :   |:....|::...||.:::.       |..|.||.|     :||...:  |:.|:..|.:.|
 Worm  1040 N---FIQVRSMKRAQDIRKQLLG-------IMDRHKLLM-----VSCGRDVSRVQKAICSGFFRN 1089

  Fly   874 IYAVDTRKSSLKSAFSGNVSMHPNTVLRDFLEPLNISAQSFRTPWIVC-NRQKSHIVYATLVV 935
            ....|.::.........||.:||::                     .| .:|...:||..||:
 Worm  1090 AAKRDPQEGYRTLTDGQNVYIHPSS---------------------ACFQQQPEWVVYHELVM 1131

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bgcn	NP_523832.2	DEAD-like_helicase_N	155..314	CDD:475120	29/117 (25%)
		ANKYR	<398..>460	CDD:440430	6/61 (10%)
		ANK repeat	406..438	CDD:293786	4/31 (13%)
		P-loop containing Nucleoside Triphosphate Hydrolases	465..>594	CDD:476819	29/129 (22%)
		HA2	687..789	CDD:461295	26/108 (24%)
		OB_NTP_bind	862..945	CDD:400182	15/75 (20%)
mog-5	NP_495019.1	GH2-like_DHX8	4..73	CDD:409668
		S1_DHX8_helicase	234..311	CDD:240189
		HrpA	538..>1157	CDD:441249	154/778 (20%)