Protein Alignment bgcn and let-355

DIOPT Version :9

• Sequence 1: NP_523832.2
• Gene: bgcn / 47873
• FlyBaseID: FBgn0004581
• Length: 1215
• Species: Drosophila melanogaster
• Sequence 2: NP_491604.3
• Gene: let-355 / 172199
• WormBaseID: WBGene00020263
• Length: 856
• Species: Caenorhabditis elegans
• Alignment Length: 970
• Identity: 171/970 - (17%)
• Similarity: 314/970 - (32%)
• Gaps: 332/970 - (34%)

  Fly    75 PKTLVLSSGATLNMFTLLSRKSLMGKEDLELYADLVSMKANASDLPSLHLPLPAIRPPNLRFWTE 139
            |||.:.:...:.|...:.:||....::....:      :||........||:.|:         |
 Worm   118 PKTPISTPSNSKNATPMSTRKHSSSQQSPPHF------EANYEKFSRPQLPIDAV---------E 167

  Fly   140 AQLNFLTAFLGHSLSDEILQSLYASRVIVYNAALCWDKSVFLPLVILDDCRNKKSNVKIMCI--- 201
            .||.:..|      |.|.|                        :||.:....|.:.|..:|:
 Worm   168 QQLMYELA------SQETL------------------------IVIGETGSGKSTQVPQLCVRAG 202

  Fly   202 ----------ERQAILATYNSQRTANFFGEQLGETVGIQLPYFSAVSSSTFIIYSTAQYFLR-SL 255
                      :.:.:.|...:.|.|...|..:|..||..:.:.:|....|.|.|.|....|| :|
 Worm   203 IANSGSIAVTQPRRVAAISLASRVATEMGTNIGGIVGYHVRFENATCHKTKIEYMTDGIVLRKAL 267

  Fly   256 TSQQFRNISHLVVNDVHLHDPYTDILLSEIRMALSSHQN----LRVVLLSQMGNPKKFTDFFGEG 316
            .|......|.:::::.|....::|:|:..:|......:.    ||::::|.....:||..:|
 Worm   268 VSPLLDKYSCVIIDEAHERSLHSDVLMCILRQCQDQRRETNNPLRLIIMSATLQAEKFQSYF--- 329

  Fly   317 LQLNMIKQPEVAPRVSYLNELHSCIALAGIHKGPDIYKEIPEAFRANNPRNEQMDKCLQAYGELG 381
               |..|...||.|...:...|.                        ||:
 Worm   330 ---NNAKVVLVAGRTFPIEVFHV------------------------NPK--------------- 352

  Fly   382 TDAALRPFLYAVNYDLAPVNYRHSLTGKTAVHFASELNKANHLRLLLFMGADPYIVDLFQQNAIS 446
                                                :||
 Worm   353 ------------------------------------INK-------------------------- 355

  Fly   447 LAAMNGNHECIDVLNSYSLHGYVVKSAKPDFVDYDLIIDIMYLLRTKPEYSPGEYSPGNILIILP 511
                           |:|...||          |:.:|.:.|:..|:|:   |.    :||:.|.
 Worm   356 ---------------SFSSTDYV----------YNAVICVKYVHLTEPK---GR----DILVFLT 388

  Fly   512 TYYHIVKLNYMILSHCLTGSLQECSIFL----LYDNMRND-YLQALVNASDETVKVVLATDIIES 571
            ....|..:...:..  |.|||...:..|    ||..:|.: ..:|.........||:::|:|.|:
 Worm   389 GSEEIEAVASQLAE--LNGSLPASADVLMPVPLYAALRPEKQKEAFRKTPQGARKVIISTNIAET 451

  Fly   572 LCLKVPFKYQIDTA----------CRLN--NVYDTTSCSGDDRFEWVAKDALLRRELILQPNKGD 624
            .......:..||:.          .|::  .|::.:......|.....:||         |.|
 Worm   452 SVTIPGIRVVIDSGKVKTKRFEAFNRIDVLKVHNVSKAQAKQRAGRAGRDA---------PGK-- 505

  Fly   625 VQCFRLISKEAYEELSETSQPSLQTMQLDKICLAVKLL---SPNTIISEYLGITISPPPLINVHH 686
              |:||.|:|.:.:....:.|.:....|....|.:..|   :|:.:      ..|.||...|::.
 Worm   506 --CYRLYSREDFHKFEAENMPEILRCNLSATFLELMKLGMKNPHRL------KLIDPPETDNINA 562

  Fly   687 AVQFLKKIDVLDDAED------VTWLGCRLMDIPVSCQLGRMLIFGILLRCLDPILTIVSSLSTA 745
            |:..|..:..:.....      :|.:|......|:.....|:|.......|:...:.||:::.|
 Worm   563 ALLELTSLGAIRPVNSDRSKFALTEMGDAFCMYPLPPDHARILFQAQKEGCIMEAIKIVAAMQT- 626

  Fly   746 DPLGIPFT--------EDIDNLWDRFTIYIQNSIKKERTYLSDNQFSDHFIFVRLYKEWQN---- 798
            |.|   |:        .|:|.:..||.....:.|...:..|..|||.|     :|.|:.::
 Worm   627 DAL---FSGAGDSKSDADVDRIRRRFETREGDHITLLKLVLVTNQFFD-----QLNKKTESDARY 683

  Fly   799 --------RMHNRTPPLYLKDEYEFMLNGLMEQLTSIRSEIVSSLRAANLIHSRGKLSMNNLNQM 855
                    |.:|:|...:..|.   |:|   ||.....|.|...|:.   |....|::.:.   .
 Worm   684 GKANKSLEREYNQTIRKFCNDN---MIN---EQHLKTASMIEEQLKQ---IAIEQKVTFST---C 736

  Fly   856 SCNWHMVKAALTGGMYPNIYAVDTRKSSLKSAFSGNVSM--HPNTVLRDFLEPLNISAQSFRTPW 918
            ..::..::.||..||:.|....|.::...:...:..:::  ||::.|
 Worm   737 GADFMKMRKALALGMFLNSCEYDRQEDRYRLMINPAITLKIHPSSCL------------------ 783

  Fly   919 IVCNRQK-SHIVYATL-----VVPLAVAMFSG---------HPRIRLSPICDSEMSLTDR 963
               :|.| ::||::.|     :..|.|.:..|         |.::|.:.:.::    |:|
 Worm   784 ---SRSKPAYIVFSELMKTNDLFALQVTLIDGDWVRPLISDHKKMRANHLAET----TER 836

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bgcn	NP_523832.2	ANK repeat	406..438	CDD:293786	2/31 (6%)
		ANK	407..>460	CDD:238125	2/52 (4%)
		Ank_2	413..>460	CDD:289560	2/46 (4%)
		HrpA	<484..973	CDD:224557	106/543 (20%)
		HA2	694..763	CDD:214852	14/82 (17%)
		OB_NTP_bind	823..945	CDD:285018	23/138 (17%)
let-355	NP_491604.3	HrpA	149..>800	CDD:224557	158/897 (18%)
		DEXDc	180..320	CDD:238005	30/163 (18%)
		Helicase_C	383..500	CDD:278689	23/118 (19%)
		HA2	569..660	CDD:214852	17/94 (18%)
		OB_NTP_bind	712..822	CDD:285018	22/136 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810