Protein Alignment vir and virma

DIOPT Version :9

• Sequence 1: NP_524900.1
• Gene: vir / 47869
• FlyBaseID: FBgn0003977
• Length: 1854
• Species: Drosophila melanogaster
• Sequence 2: XP_005158091.1
• Gene: virma / 560260
• ZFINID: ZDB-GENE-100922-238
• Length: 1850
• Species: Danio rerio
• Alignment Length: 2094
• Identity: 514/2094 - (24%)
• Similarity: 818/2094 - (39%)
• Gaps: 543/2094 - (25%)

  Fly     5 DDGSELLFFDTFSHEEVTDINLDLVQFPKPVFITQVRIIPLGARVQADFPGGVRLGATNPSKFDL 69
            |...||||.|||.|:.....|:|:|:||..|.||:||:||.|.:..::.|.....|.|.|..|.|
Zfish     4 DSAMELLFLDTFKHQNAELTNVDVVRFPYGVLITEVRVIPPGIKAHSNLPDSRAFGETAPHAFQL 68

  Fly    70 EFFVNDLGMPAASAFENLGLLRYNQNDCIHLDCSQEKIVTDGLVLRGWYSTITLAIYGIFTNSVT 134
            :.|.|::..|.:..|:.||.|.|::|..| :.....||.||||||||||:.:|||:||
Zfish    69 DLFFNNVSKPNSPVFDRLGSLEYDENKSI-IFRPNGKINTDGLVLRGWYTCLTLAVYG------- 125

  Fly   135 EPIASPTLPCEPVGPEIANLSGEVLLQEDVLKDEWQEPMQAELLTAHKGNVSDYDPEDMEYGMSR 199
                                                        ||                 .|
Zfish   126 --------------------------------------------TA-----------------ER 129

  Fly   200 DHYHQHAEEQEQREMRRLRRSTHSTDHSPPPPRRSHTHSESNDREYIRCSRDKGSRDWSRSPEYS 264
            .|                   :|..|..||||.......:...:..|:.       :|....:::
Zfish   130 PH-------------------SHERDSPPPPPPPPPQQQQIGSKRLIKL-------EWENEDQFN 168

  Fly   265 SHRSRRKRSERSRSVVDEHKWPRTPPASIDSPTRPRSPDTMDYEDEDSRSHYKMQSSHYRHSSE- 328
            ....|           .:.:.|||||.       |..||..|.|...:.....::..:..|..:
Zfish   169 GSPPR-----------PQPRGPRTPPG-------PPPPDDDDEEAMPAPGQCPVKVENTEHPGDD 215

  Fly   329 -----SLHRGE-------RDRDDEDRSCTPQEQFEPILSD----DEIIGDDEEDDAVDAAA---- 373
                 |..||.       .|.:.||......|:.:.:.|:    ||   |||||:..|...
Zfish   216 YLEPVSPERGSLPADETYSDAEQEDDEGPADEEEDDVQSEGTEGDE---DDEEDEVGDDVTDEDG 277

  Fly   374 --------IAEYERELEAAAAAAP--------------PAI--DAFEPWQKPLLVFEGDMAAHFC 414
                    |:..|.:||:.|...|              |.:  |.:|...:||..|.......:.
Zfish   278 EGDDGYEQISSDEEDLESGAFKLPAFDLDYTPEDLASLPTVQYDPYERELRPLQHFTPPHITRYE 342

  Fly   415 KELETLKLL------------FKKLVLQTRCENVNAFSEEHGA--------SVDEREQFVYLGEQ 459
            .||:.||.:            ..||     .|.:.|:.|..||        :::|...|:..|
Zfish   343 AELKRLKTVDIEDSSSSWAESAAKL-----SELLEAWGEAQGAERGAGWVTALEEVPAFLVKG-- 400

  Fly   460 LNNQLGYLAQHYKRRNFVLQQFFGNDELHLRQAANVLQIALSFQAACMQPQPAFKIRHIKLGARM 524
                :.:|:         ::...|..| .|:|..:....|||...|..|| .|..:|.:|.|.::
Zfish   401 ----MSFLS---------IKDPDGQSE-KLKQLVDWSCEALSLDVALAQP-IALNLRQLKAGTKL 450

  Fly   525 AELLGS-SEELFQHLLKEHKFDIFEAVFRLYHEPYMALSIKLQLLKAVYALLDTRMGIE------ 582
            ...|.. ..:..|.||::   .|...:..|....:::.::||.:|:::.:::....|||
Zfish   451 VSALADCGAQAVQDLLEK---GIVGRLLGLLFAEHVSSTLKLNVLRSLDSIISEPQGIEAMLRDR 512

  Fly   583 -HFMGAKNNGYQMIVEAIKTAKLTRTKYALQAIIKKLHLWEGLESVQ----IWCRRLFVDRIIIP 642
             |......:|||.:::.....:..|...|..||:.|.||:|.|..:|    :|..|       .|
Zfish   513 HHHDDDGTSGYQRLLDLFLLDQTVRVATAGAAILHKGHLYEVLTDLQKTASVWAER-------HP 570

  Fly   643 ---------------GNRD------QMEDTVITCQQIEFAFEMLMDALFSS------QLSYLQ-- 678
                           |.||      :.|:.....|:.|....|.:|.|..|      .|..||
Zfish   571 TVGEVAEREGSESEAGERDRESTEREGEERERETQEAERESPMDIDTLLESASLSEADLERLQGL 635

  Fly   679 ------------------PRRFLPVSKKFEVVTDPTAQRSFGNALQSYLGQNSLAESLLVMLANC 725
                              |.:..|.:.:   :|.|..:......|..|:....|.|||.|:|:
Zfish   636 LEELLHLLETAPHCMVQPPGKAFPTNVR---ITGPPERDDPYPTLYRYMHACHLLESLGVVLS-- 695

  Fly   726 KELPAT-TYLSML----DLMHTLLRSHVGIDYFVDDAFPVTQTIVAILLGLDEV-------PRNP 778
              .||| .::.:|    :||..|.:|..|: .|:.........::.:|..|..:       |..|
Zfish   696 --YPATCAHIGVLQAVRELMRFLSQSQQGL-LFLLSQHETINLLLRLLTPLTHLTPPSHLAPLTP 757

  Fly   779 EEKEEKAEKSDAEDKAMEVENEAVEAGGEKPTPPTADEEGKPVAAPISVPAPAAAPQVRPRPILR 843
                           ..|||.|...||||     ...::|..|
Zfish   758 ---------------LSEVEGEEAAAGGE-----GLMDDGFWV---------------------- 780

  Fly   844 PVLPRLARLGIEMSYKVQTRYHLDAIAYAAAAPEYDAVK---LATHMHAIYSQTCDPAGRQHTVE 905
                          :.:||.:.|..||....|...|...   ||| :|::|..:....||.....
Zfish   781 --------------WLMQTLHALQGIAELNGAELEDGDNPDVLAT-LHSLYLISFSSTGRNAVAH 830

  Fly   906 VLGLNNNLKIFMDLIKKEQRLQTQRQLSSPGTKYKSPVLSYAVDMVDACVRYCEQLDYLIEHGGV 970
            ...|:|||...::||:..     .:.....|...||...:||..:|...::....|..:..:...
Zfish   831 TFSLDNNLSCLINLIEFH-----AKDGQGDGKARKSVTYNYACMLVLLVIQTSSDLRMMEHYAAP 890

  Fly   971 ILELAKNHETFEPSVSAVLQEMYVYMKPLEAINVFVYDDIMPLVEVIGRSLDYLTTFPG-DLIMA 1034
            :|.:.|..|.     :|.|||:..:::|||.:: |....|..|::.|.::|:.|.|..| .|:.|
Zfish   891 LLLVCKADEN-----NAKLQELSKWLEPLEKLH-FDISGIPMLIDYIKQNLENLMTADGVGLVTA 949

  Fly  1035 MRILRYLSISKPLAGQKAPPVT-----EELKHRFVALQLYAADGVQLCIQIMERLCAYFEQP-GA 1093
            :|:|.:::         .||.|     ::||.....:.|::|:|:...|:::::|.:....| ..
Zfish   950 LRVLCHIA---------CPPATVPGQQKDLKWNQAIIALFSAEGMDTFIKVLQKLTSLLLLPWRL 1005

  Fly  1094 HAPALMTIQGVHCCQIMLPTLQILRELLSYAILCRDGT--YKDLTAIDHLVKVYYLLYYFPTRCQ 1156
            |.|...|.|.:....:...:|:::|.:|: .:|| .||  ::|:......|.::.:|...|:..:
Zfish  1006 HGPMGPTAQRLMMLSVASCSLRLIRAMLT-ELLC-GGTCEFRDVRVPSVCVTLHKILCSTPSTGR 1068

  Fly  1157 AGPEVEQCKMEVVQTLLAYTQP-NEQD---EESLHKSLWTLMIREVLKNV-DGPAHFIPGLKLLA 1216
            ...|..:.:.:|.:.||.:|.. :||:   ||::..:.|:||::|||.:: ..|.:....|.||:
Zfish  1069 LDAEELRIQGDVTEILLTFTHAVSEQETGSEETVAGNSWSLMLKEVLNSILAAPENIYSSLSLLS 1133

  Fly  1217 ELLPLPLPMPQPLCDQLQQQHKQRLITERKLWSAHLHPQSGQIAKLVEALAPSSFPQLSELLQRV 1281
            |||||||||  .....|..|.....:..|||||.|||.|:..:.:::.....||.|.|..:|:||
Zfish  1134 ELLPLPLPM--QTTQALSVQDIGVAMNTRKLWSVHLHAQARVLQEVLRCACVSSCPPLFSMLRRV 1196

  Fly  1282 CMQLSDLAPNMTLLIAKTITELLCNEYQTSNCIPTTNLERLLRFSTRLCAFAPLKSSMLSILSG- 1345
            |:||.|||.....|:.:|:.|.|..|.|..  ...:.|.|:|.....|.:....|.:||::|||
Zfish  1197 CVQLCDLAAPTATLVMRTLLEQLQEEMQQE--AAGSRLIRVLALLDSLASQRACKVAMLALLSGS 1259

  Fly  1346 -------------KFWELFQSLLALNEF-NDVVSNCQ---EAVHRILDSFLDSGISLI---SHKS 1390
                         |..::..||||:... .||..:.|   |.:..||.|..|..:||:   |.::
Zfish  1260 ARSDTRSEGKVEDKLSDILPSLLAMLVLPADVGLSAQQNAELMASILQSLCDQDVSLVVSGSGEA 1324

  Fly  1391 TASPALNLAAALPPKELIPRIIDAVFSNLTSVEVTHGISILAVRNLVILTEHDFTFYHLAQLLKQ 1455
            :.|.|..||.|||.||::..|.:.:...|.:...::.:.:..:|.::.|||||:..|||...||:
Zfish  1325 SVSEAELLANALPTKEMMTSICEGMLDVLGNTHSSYTLQLTCLRTMMFLTEHDYGLYHLKSSLKK 1389

  Fly  1456 KITEFQAWMERVILHNETVEYNANI-ESLILLLRSLTQIEPPPAM---SA----------MPHRT 1506
            ..|...:     ::..|...:|... |.|..|...|.||....||   ||          |..|:
Zfish  1390 HTTAISS-----LIRREITSFNKEFAELLSALFDFLRQILNSEAMFLRSAFYRHHHADEDMDSRS 1449

  Fly  1507 LKLGATELAQLVEFQDIELAKPPVLSRILTVMEKH--KAVANEAALSDLKQLILLQASKQEILAG 1569
            |.|..:::.||:::      |......:|..:|||  |....:.:|..|.:.::   ..::|:
Zfish  1450 LALSVSDMKQLLQW------KEDSGEHLLCELEKHITKLCKEDESLEALLENVV---GLRQII-- 1503

  Fly  1570 TSTETPPEAEGEANPSASSCSASLTVEPYLPQAEGIVTQYEARPIFTRFCATAENAQLTARYWLD 1634
                   |:.|:|..:|..     ..||.||..|.:.||:..|.::.  .:...:.||.| .|..
Zfish  1504 -------ESSGDAQTNAEP-----ETEPSLPAPEPLQTQFNHRTVYV--LSDVLDEQLKA-LWFS 1553

  Fly  1635 PL-PIELIEDMNEPIYERIACDLTDLANVCLNPDLNVAGDSKRVMNLSGSPQSNREMTPTA---- 1694
            |. |.|:     |...:.:..||..||..|.. :|::..:.:|  :....|.|.....|:.
Zfish  1554 PFQPDEM-----ETEVDMVKVDLVALAQQCCT-ELDLKAELER--SFLSEPSSPGHSKPSKGFRL 1610

  Fly  1695 -----PCFRTRRVE------VEPATGRPEKKMFVSSVRGRG------FARPPPSRGDLFRSRPPN 1742
                 ..|.|.|..      ||||    ::...:::.||||      .:||    .|:||.|..|
Zfish  1611 GKHKHETFITSRYTSGRSDYVEPA----KRAHIMAAPRGRGRGSFGQLSRP----HDIFRQRKQN 1667

  Fly  1743 TSRPPSLHVDDFLALETCG-AQPTGPT--------GYNKIPSMLRGSRVGRNRGSRISAAAAF-- 1796
            ||||||:|||||||.|... ..|||.|        |..|.|:  ||...|..||....:...|
Zfish  1668 TSRPPSMHVDDFLAAEFKDVGPPTGLTLPKRPPKGGGAKPPT--RGMFTGGTRGRGFQSHTRFFT 1730

  Fly  1797 --RQKKMMRIGS--------PSSWAESP-------GSYRSASDSHFSSSDSHYSSP--------- 1835
              ..|.::..|:        .|:|: :|       |:|     |......|:::.|
Zfish  1731 PPAPKSVLLAGNYPRREGGRGSTWS-TPVTAVTHRGTY-----SEPRGGQSNFTRPLPSRQPPTG 1789

  Fly  1836 HYSGRPRGRGLRSR 1849
            .|...||.|..|.|
Zfish  1790 AYRLAPRDRATRGR 1803

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vir	NP_524900.1	VIR_N	6..263	CDD:292534	66/256 (26%)
virma	XP_005158091.1	VIR_N	5..254	CDD:292534	85/361 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574121
Domainoid	1	1.000	299	1.000	Domainoid score	I1415
eggNOG	1	0.900	-	-		E1_KOG4822
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	387	1.000	Inparanoid score	I1963
OMA	1	1.010	-	-		QHG48370
OrthoDB	1	1.010	-	-		D114891at33208
OrthoFinder	1	1.000	-	-		FOG0006529
OrthoInspector	1	1.000	-	-		oto39901
orthoMCL	1	0.900	-	-		OOG6_107758
Panther	1	1.100	-	-	LDO	PTHR23185
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5505
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.770