Protein Alignment crc and ATF7

DIOPT Version :10

• Sequence 1: NP_524897.1
• Gene: crc / 47767
• FlyBaseID: FBgn0000370
• Length: 381
• Species: Drosophila melanogaster
• Sequence 2: NP_001353484.1
• Gene: ATF7 / 11016
• HGNCID: 792
• Length: 494
• Species: Homo sapiens
• Alignment Length: 413
• Identity: 88/413 - (21%)
• Similarity: 146/413 - (35%)
• Gaps: 111/413 - (26%)

  Fly    61 IGDDEALTLEEVASLQLLSDE----------EMVVEIFDLK-DEECLLDQKAT-----LNCIDYD 109
            :|||...........|..::|          ||.::....: |...:.||..|     .||.:..
Human     1 MGDDRPFVCNAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARTDSVIIADQTPTPTRFLKNCEEVG 65

  Fly   110 -----SNSFQPNINVI-------TQAIVPANKVQFGASSDAASLPSAADYQLNDGPSLILQQLTP 162
                 ::||:......       .::...|.|:...|.....||||..|.::.:...:.:.. :|
Human    66 LFNELASSFEHEFKKAADEDEKKARSRTVAKKLVAAAGPLDMSLPSTPDIKIKEEEPVEVDS-SP 129

  Fly   163 PQSP---PQFDAYKQAGDAQPKPVLVKAEQKVQCYTPDVTHAAS--------------------- 203
            |.||   |.....|:. :..|||||:...      ||.:....|
Human   130 PDSPASSPCSPPLKEK-EVTPKPVLISTP------TPTIVRPGSLPLHLGYDPLHPTLPSPTSVI 187

  Fly   204 --ATPFNFTNWVG---GS---------------------------EIARENQLVDDIVNMRAKEL 236
              |.|.|  ..:|   ||                           .:||...:|.:|..:....:
Human   188 TQAPPSN--RQMGSPTGSLPLVMHLANGQTMPVLPGPPVQMPSVISLARPVSMVPNIPGIPGPPV 250

  Fly   237 ELSTNWQQLNEDCESQASSSLDSR-----STGSGVCSSIADADEDWV---PE----LISSSSSPA 289
            ..|.:.........|:|...|.:.     |:.:|.|..:.......|   ||    ||....:|:
Human   251 NSSGSISPSGHPIPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQSQILIQHPDAPS 315

  Fly   290 PTTIEQSASQPK-----KRTRTYGRGVEDRKIRKKEQNKNAATRYRQKKKLEMENVLGEEHVLSK 349
            |...:.|.:||.     :|.||.....::|:.|..|:|:.||:|.|||:||.:.::..:...|:.
Human   316 PAQPQVSPAQPTPSTGGRRRRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSSLEKKAEELTS 380

  Fly   350 ENEQLRRTLQERHNEMRYLRQLI 372
            :|.||...:....||:..|:||:
Human   381 QNIQLSNEVTLLRNEVAQLKQLL 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
crc	NP_524897.1	bZIP_ATF4	313..374	CDD:269840	21/60 (35%)
		coiled coil	315..374	CDD:269840	20/58 (34%)
ATF7	NP_001353484.1	C2H2 Zn finger	9..31	CDD:275370	2/21 (10%)
		GCN4_cent	47..84	CDD:213399	7/36 (19%)
		bZIP_ATF2	345..405	CDD:269835	21/59 (36%)
		coiled coil	345..405	CDD:269835	21/59 (36%)