DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment c(3)G and ZYP1b

DIOPT Version :9

Sequence 1:	NP_650490.1	Gene:	c(3)G / 47765	FlyBaseID:	FBgn0000246	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_564164.1	Gene:	ZYP1b / 838834	AraportID:	AT1G22275	Length:	856	Species:	Arabidopsis thaliana

Alignment Length:	801	Identity:	171/801 - (21%)
Similarity:	318/801 - (39%)	Gaps:	243/801 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 FERSNEKPSKKRTPLVAPRVQQSKIE----AQTSQAVEKTQEDQTFAAT-IDSSTKSLKKS---- 103
            |::....|...:|...:.|..|..:.    :......||..:||....| ::.:...||||
plant    12 FDQLRSLPGSAKTYFFSTRPPQDSVSSGSFSNLKLTAEKLVKDQAAMRTDLELANCKLKKSMEHV 76

  Fly   104 --------------------PKNEGELWADIQKLSPHTGIIIHSFIKQYNESLNNL--------K 140
                                .|.:.:||..::.....|    .:...|..|:|.:|        |
plant    77 YALEEKLQSAFNENAKLRVRQKEDEKLWRGLESKFSST----KTLCDQLTETLQHLASQVQDAEK 137

  Fly   141 KKDLVVSK-KMRAIAMDSLKKKSENISL-----KEKLTNMELELTQLKTDLIEQQEKNAENIQKY 199
            .|....:| ...:.|::||.::..::||     ||::|:.:.||.:||   :|:|
plant   138 DKGFFETKFNTSSEAINSLNQQMRDMSLRLDAAKEEITSRDKELEELK---LEKQ---------- 189

  Fly   200 TEINKKYTHCEQHYDKELEIIKVCVEKKN---SELRDAQSRMALQAQELNNMQQTNRELAGACEN 261
                    |.|..|..|.......:|||:   :||....:...|:.::||:
plant   190 --------HKEMFYQTERCGTASLIEKKDAVITELETTAAERKLKIEKLNS-------------- 232

  Fly   262 YKKDLEEAEVAKSMILH-ELTDLKELHEDLQLQFEDVSAQKEKFEANILQLSSD-LNAKMLDCAQ 324
               .||:        || |||    ..||..:....:..:.||.:.|: ||||| |..|::...|
plant   233 ---QLEK--------LHLELT----TKEDEVIHLVSIQEKLEKEKTNV-QLSSDELFEKLVRSEQ 281

  Fly   325 LEDRIEQLPIEANKALSKLQRDLEASELQF-------------------VDQQRLTDQATRELEL 370
            ...::::|   .:..:::| .:|:...|.|                   .|:...:|:|.|..:.
plant   282 EVKKLDEL---VHYLIAEL-TELDKKNLTFKEKFDKLSGLYDTHFMLLRKDRDLASDRAQRSFDQ 342

  Fly   371 VRNEINTFKTLIEEKERRHVSLSDELTQMTERLSELADINESYINELTETKLKHSQEI-KDQADA 434
            ::.|:  |:...|::     :|.....:::|::.||.:..||.|::|:..:...||.| |.:.:|
plant   343 LQGEL--FRVAAEKE-----ALESSGNELSEKIVELQNDKESLISQLSGVRCSASQTIDKLEFEA 400

  Fly   435 ---------YEIVVQELKESLN--------------KASVDFTQL----KSNSEKLHKETLLQVS 472
                     .|.|:.:|||.::              :.|:..:.|    |...|||..:...||.
plant   401 KGLVLKNAETESVISKLKEEIDTLLESVRTSEDKKKELSIKLSSLEIESKDKYEKLQADAQRQVG 465

  Fly   473 ELQEKLIEMVSHRSNQEELIK---RLGNEIQEKTH----------NFEEELKRQQEQLAN----- 519
            ||:....|..||:...:.|.|   :|...|:||.|          |..:::.:.:|.||.
plant   466 ELETLQKESESHQLQADLLAKEVNQLQTIIEEKGHLILQCNENEKNINQQIIKDKELLATAETKL 530

  Fly   520 ---------QMQMKATEVESE----NKRNAVEIQKLKSELE-ERNKAFKAQQDKLEYLISDHDT- 569
                     .::.|..|:...    ::||...|.:::.:.: |:::...:::||:|.:|.:..|
plant   531 AEAKKQYDLMLESKQLELSRHLKELSQRNDQAINEIRRKYDVEKHEIINSEKDKVEKIIKELSTK 595

  Fly   570 -----------LKSAIINLQAE--------KKEIESELSTAKVKFSEEL---QSQKDNLMKK--- 609
                       .|..::.:|.|        ::|.||:....|.|:.:||   |.|.:|.:|:
plant   596 YDKGLSDCKEESKRQLLTIQEEHSSRILNIREEHESKELNLKAKYDQELRQNQIQAENELKERIT 660

  Fly   610 --VSELELEIK----------RKETELIELER---EKNNEMAVLQFKMNRINCLIDQPVTTIK-- 657
              .||.:.::|          :|..|.::|:|   |:...:..||:|:...|...:|.|.:.|
plant   661 ALKSEHDAQLKAFKCQYEDDCKKLQEELDLQRKKEERQRALVQLQWKVMSDNPPEEQEVNSNKDY 725

  Fly   658 -----QLKDSK--GPTRTESI 671
                 ::|:|:  |..|:|.|
plant   726 SHSSVKVKESRLGGNKRSEHI 746

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
c(3)G	NP_650490.1	iSH2_PI3K_IA_R	363..>516	CDD:304922	44/193 (23%)
ZYP1b	NP_564164.1	ATP-synt_B	<489..595	CDD:304375	19/105 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23160
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100