Protein Alignment c(3)G and CCDC73

DIOPT Version :9

• Sequence 1: NP_650490.1
• Gene: c(3)G / 47765
• FlyBaseID: FBgn0000246
• Length: 744
• Species: Drosophila melanogaster
• Sequence 2: NP_001008392.2
• Gene: CCDC73 / 493860
• HGNCID: 23261
• Length: 1079
• Species: Homo sapiens
• Alignment Length: 740
• Identity: 157/740 - (21%)
• Similarity: 290/740 - (39%)
• Gaps: 223/740 - (30%)

  Fly    83 TQEDQTFAATIDSSTKSLKKSPKNEGELWADIQKLSPHTGIIIHSFIKQYNESLNNLKKKDLVVS 147
            |:...||  |:.||:::|           ..||.|...|.::         |:|..|:
Human     7 TESSSTF--TLQSSSETL-----------FSIQLLDFKTSLL---------EALEELR------- 42

  Fly   148 KKMRAIAMDSLKKKSENISLKEKLTNMELELTQLKTDLIEQQEKNAENIQKYTEINKKYTHCEQH 212
                      :::::| |..:|::..:.:|..:||.             ||.|..|:|.|..|||
Human    43 ----------MRREAE-IHYEEQIGKIIVETQELKW-------------QKETLQNQKETLAEQH 83

  Fly   213 ------YDKELEIIKVCV--EKKNSELRDAQSRMALQAQELNNMQQTNRELAGACENYKKDLEEA 269
                  :.|:|: :|:|.  |:|..    .|....::.:|:..:::|.:.|..:..:.:|.:.|.
Human    84 KEAMAVFKKQLQ-MKMCALEEEKGK----YQLATEIKEKEIEGLKETLKALQVSKYSLQKKVSEM 143

  Fly   270 E-------VAKSMILHELTDLKELHEDLQLQFEDVSAQKEKFEANILQLSSDLNAKMLDCAQLED 327
            |       :||.....:|:::::.:..:..||..|....||.|.|:.:
Human   144 EQKVQLHLLAKEDYHKQLSEIEKYYATITGQFGLVKENHEKLEQNVRE----------------- 191

  Fly   328 RIEQLPIEANKALSKLQRDLEA------SELQFVDQQRLTDQATRELELVRNEINTFKTLIEEKE 386
                 .|::||.||.|.:..||      .||:......:..:.|.:.::....||.  |:.|:|
Human   192 -----AIQSNKRLSALNKKQEAEICSLKKELKKAASDLIKSKVTCQYKMGEENINL--TIKEQK- 248

  Fly   387 RRHVSLSDELTQMTERLSELADINESYINELTETKLKHSQEIK-DQADAYEIVVQELKESL---N 447
                     ..::.|||:...::||....|:|     |.||.| |...:::.:.|.|::.:   .
Human   249 ---------FQELQERLNMELELNEKINEEIT-----HIQEEKQDIIISFQHMQQLLRQQIQANT 299

  Fly   448 KASVDFTQLKSNSEKLHKETLLQ---VSELQEKLIEMVSH--------RSNQEEL---IKRLGNE 498
            :...:...||.|::.|.::..||   |.|.:||.:.:.:.        :.:.|||   |.::.||
Human   300 EMEAELKVLKENNQTLERDNELQREKVKENEEKFLNLQNEHEKALGTWKRHAEELNGEINKIKNE 364

  Fly   499 IQ--EKTH--------------NFEEELKRQQEQLANQMQMKATEVESENKRNAVEIQKLKSELE 547
            :.  ::||              .|||:.|.|.....|.   :.:|:.:|...|.: |||..:|.|
Human   365 LSSLKETHIKLQEHYNKLCNQKTFEEDKKFQNVPEVNN---ENSEMSTEKSENTI-IQKYNTEQE 425

  Fly   548 ERNK---------AFKAQQDKL------EYLISDHDTLKSAI---INLQAEKKEIESELSTAK-V 593
            .|.:         .::.:::|.      |.:|.|....:.:.   |:....:.|.:||:|.:| :
Human   426 IREENMENFCSDTEYREKEEKKEGSFIEEIIIDDLQLFEKSFKNEIDTVVSQDENQSEISLSKTL 490

  Fly   594 KFSEEL--QSQKDNLMKKVSELELEIKRK--------------------------ETELIELERE 630
            ...:|:  |.|..|:......:..|||.|                          |||.|.|||.
Human   491 SLDKEVISQGQTSNVTDNRKSVTTEIKDKICLEKDNGCTEFKSPNNHFVVLDTAIETEKIHLERT 555

  Fly   631 KNNEM----AVLQFKMNR--INCLIDQPVTTIKQLKDSKGPTRTESIPTKVQPENTDEFSSTARK 689
            :..::    ..|:.:.|:  .|.::::   |......:.....:|:.|.|       :|......
Human   556 RGLDVHHTDVNLEVENNKTSFNSILNE---TAHNTYHNNNKDVSENEPFK-------QFRLLPGT 610

  Fly   690 RNARRQKITTYS----SDFDSGDDI 710
            |....:|..|.|    :|.||..||
Human   611 REHALEKEITNSDQTKADLDSSLDI 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
c(3)G	NP_650490.1	iSH2_PI3K_IA_R	363..>516	CDD:304922	43/186 (23%)
CCDC73	NP_001008392.2	CCDC73	27..1070	CDD:292446	148/707 (21%)
		BAR	<47..220	CDD:299863	48/213 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1052..1079

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000