DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Amy-p and IMA2

DIOPT Version :9

Sequence 1:	NP_001286518.1	Gene:	Amy-p / 47764	FlyBaseID:	FBgn0000079	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_014485.1	Gene:	IMA2 / 854008	SGDID:	S000005517	Length:	589	Species:	Saccharomyces cerevisiae

Alignment Length:	366	Identity:	78/366 - (21%)
Similarity:	126/366 - (34%)	Gaps:	125/366 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 WDD---IAAECENFLGPNGYAGVQVSPVNENAVKDSRPWWERYQPISYK--LETRSGNEEQFASM 98
            |.|   ||::.| ::...|...:.:||..::...|.     .|...:|:  ..|...||:.|| :
Yeast    36 WGDMKGIASKLE-YIKELGADAIWISPFYDSPQDDM-----GYDIANYEKVWPTYGTNEDCFA-L 93

  Fly    99 VKRCNAVGVRTYVDVVFNHMAAD-------------------------GGTYGTGGSTASPSS-K 137
            :::.:.:|::...|:|.||.:::                         |  |...|....|:: :
Yeast    94 IEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKG--YDAEGKPIPPNNWR 156

  Fly   138 SYPGVPYSSLD-----FNPTCAISNYNDAN-EVRNCELVGLRDLNQGNSYVQDKVVEFLDHLIDL 196
            ||.|....:.|     |......|...|.| |..:|.          .:..:..|..:|||
Yeast   157 SYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCR----------KAIYESAVGYWLDH---- 207

  Fly   197 GVAGFRVDAA-----------------KHMW-PADLAVIYG-RLKNLNTDHGFASGSKAYIVQEV 242
            ||.|||:|..                 ...| |:|...:.| |:      |.|......:|...|
Yeast   208 GVDGFRIDVGSLYSKVAGLPDAPVIDENSKWQPSDPFTMNGPRI------HEFHQEMNKFIRNRV 266

  Fly   243 IDMGGEAISKSE-----------YTG-----LGAITEFRHSD-SIGKVFRGKDQLQY-LTNWGTA 289
            .| |.|.::..|           ||.     |..:..|.|:| .....|| ::.:.| |.:|..|
Yeast   267 KD-GREIMTVGEMQHATDETKRLYTSASRHELSELFNFSHTDVGTSPKFR-QNLIPYELKDWKVA 329

  Fly   290 -------------WGFAASDRSLVFVDNHDNQRGHGAGGAD 317
                         |       |.::::|||..|.....|.|
Yeast   330 LAELFRYVNGTDCW-------STIYLENHDQPRSITRFGDD 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Amy-p	NP_001286518.1	AmyAc_bac_euk_AmyA	28..399	CDD:200456	78/366 (21%)
		Alpha-amylase	54..342	CDD:278554	73/348 (21%)
		Aamy_C	405..493	CDD:214749
IMA2	NP_014485.1	AmyAc_SI_OligoGlu_DGase	16..503	CDD:200472	78/366 (21%)
IMA2	NP_014485.1	Malt_amylase_C	514..585	CDD:406946
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342133
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830