DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Amy-p and zgc:158423

DIOPT Version :9

Sequence 1:	NP_001286518.1	Gene:	Amy-p / 47764	FlyBaseID:	FBgn0000079	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_001073552.1	Gene:	zgc:158423 / 790938	ZFINID:	ZDB-GENE-061215-58	Length:	480	Species:	Danio rerio

Alignment Length:	355	Identity:	73/355 - (20%)
Similarity:	117/355 - (32%)	Gaps:	132/355 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 SGRSGMVHLFEWKWDDIAAECENFLGPNGYAGVQVSPVNENAVKDSRPWWERYQPISYKLETRSG 90
            ||..|:    |.|.|        :|.....|||.:.|::...:..    .:....||.:.|.  |
Zfish   110 SGLKGL----EGKLD--------YLSQMNVAGVVLGPIHSLKIDQ----LDTLNLISVQSEV--G 156

  Fly    91 NEEQFASMVKRCNAVGVRTYVDVV---------FNHMAA------DGGTYGTGGSTASPSSKSYP 140
            .|.:..|::...:..|:...:::.         ||:..|      |..||..        .|...
Zfish   157 TENELESLLGLAHKKGIFIVLNLTPNFNKTSAWFNNFNAVAEKIKDACTYWL--------DKGLD 213

  Fly   141 GVPYSSLDFNPTCA------ISNYNDA---------------NEVR--------NCELVGLRDLN 176
            |:..|.|:..||.|      |.|.:||               |::.        :..|.|..||:
Zfish   214 GIFLSDLNEIPTDAWPSIKEIFNRSDATKEVALMGSVNSMSVNDISVLLNRSGVDLLLTGQPDLS 278

  Fly   177 QGNSYVQDKVVEFLDHLIDLGVAGFRVDAAKHMWPADLAV-----IYGRLKNLNTDHG---FASG 233
            .... .|.::::..:..|.....|:|    ....|..||.     :|..|  |.|..|   |::|
Zfish   279 DSGE-KQAQIIKEFNSSIQQTSLGWR----SRQDPGTLAAEFPIRLYQIL--LFTLPGTPVFSAG 336

  Fly   234 -------------------------SKAYIVQE-----------VIDMGGE--AISKSEYTGLGA 260
                                     :||..:||           :.|:.|:  ::...||.||.
Zfish   337 EELGLKAEEQLQALWDLENPVEEKNAKAKALQEERLAVRNFFKTLSDLRGKERSLQHGEYVGLS- 400

  Fly   261 ITEFRHSDSIGKVFRGKDQ-LQYLT--NWG 287
                 :|.|.....|..|| .:::|  |||
Zfish   401 -----NSKSSLAFLRVWDQSKRFITALNWG 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Amy-p	NP_001286518.1	AmyAc_bac_euk_AmyA	28..399	CDD:200456	71/353 (20%)
		Alpha-amylase	54..342	CDD:278554	66/327 (20%)
		Aamy_C	405..493	CDD:214749
zgc:158423	NP_001073552.1	SLC3A2_N	29..98	CDD:292647
		AmyAc_family	81..391	CDD:298606	60/313 (19%)
		AmyA	99..446	CDD:223443	73/355 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900