DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Amy-p and Slc3a2

DIOPT Version :9

Sequence 1:	NP_001286518.1	Gene:	Amy-p / 47764	FlyBaseID:	FBgn0000079	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_062156.2	Gene:	Slc3a2 / 50567	RGDID:	3073	Length:	566	Species:	Rattus norvegicus

Alignment Length:	474	Identity:	89/474 - (18%)
Similarity:	153/474 - (32%)	Gaps:	188/474 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 ECENFLGP--NGYAGVQ---------------VSPVNENAVKDSRPWWERYQPISYKLETRSGNE 92
            :.:.|:||  .|.||::               :.|:::|. ||     |..:....:::...|::
  Rat   161 DLQAFVGPEARGIAGLKNHLEYLSTLKVKGLVLGPIHKNQ-KD-----EVNETDLKQIDPDLGSQ 219

  Fly    93 EQFASMVKRCNAVGVRTYVDVVFNHMAADGGTYGTGGSTASPSSKSYPGVPYSSLDFNPTCAISN 157
            |.|..:::                                |...||.    :..||..|     |
  Rat   220 EDFKDLLQ--------------------------------SAKKKSI----HIILDLTP-----N 243

  Fly   158 YNDANE---VRNCELVGLRDLNQGNSYVQDKVVEFLDHLIDLGVAGFRVDAAKHMWPAD--LAVI 217
            |...|.   ....::|..:.....:|::||            ||.||:|.....:..|.  ||..
  Rat   244 YKGQNAWFLPPQADIVATKMKEALSSWLQD------------GVDGFQVRDVGKLANASLYLAEW 296

  Fly   218 YGRLKNLNTDHGFASGSKAYIVQEVID---------MGGEAISKSEYTGLGAITEFRHSDSIGKV 273
            ....||.:.|....:|:.:..:|::::         :....:|:..:||       .|::.:
  Rat   297 QNITKNFSEDRLLIAGTASSDLQQIVNILESTSDLLLTSSYLSQPVFTG-------EHAELL--- 351

  Fly   274 FRGKDQLQYLTNWGTAW-GFAASDRSLVFVDNHDNQRGHGAGGADVLTYKVPKQYKMASAFMLAH 337
                 .::||...|:.| .::.|.                   |.:||..:|.|:......:|..
  Rat   352 -----VIKYLNATGSRWCSWSVSQ-------------------AGLLTSFIPAQFLRLYQLLLFT 392

  Fly   338 PFGTPRVMSSFSFTDTDQG--PPTTDGHNIASPIF---NSDNSCSGGWVCEHRWRQIYNMVAFRN 397
            ..|||    .||:.| :.|  .....|..:.:|..   .|.||            |..:.|:...
  Rat   393 LPGTP----VFSYGD-ELGLQAVALPGQPMEAPFMLWNESSNS------------QTSSPVSLNM 440

  Fly   398 TV-GLDEIQNWWDNGSNQISFSR--------------------GSRGFVAF-----NNDNY---- 432
            || |.:|     |.||....|.|                    .|.|..::     .|:.|
  Rat   441 TVKGQNE-----DPGSLLTQFRRLSDLRGKERSLLHGDFDALSSSSGLFSYVRHWDQNERYLVVL 500

  Fly   433 ---DLNSSLQTG---LPAG 445
               |:..|.:.|   ||||
  Rat   501 NFQDVGLSARVGASNLPAG 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Amy-p	NP_001286518.1	AmyAc_bac_euk_AmyA	28..399	CDD:200456	69/390 (18%)
		Alpha-amylase	54..342	CDD:278554	53/317 (17%)
		Aamy_C	405..493	CDD:214749	16/76 (21%)
Slc3a2	NP_062156.2	SLC3A2_N	85..156	CDD:292647
		AmyAc_family	139..469	CDD:298606	78/422 (18%)
		AmyA	159..514	CDD:223443	85/467 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900