DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Amy-p and Mal-B2

DIOPT Version :9

Sequence 1:	NP_001286518.1	Gene:	Amy-p / 47764	FlyBaseID:	FBgn0000079	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_001188791.2	Gene:	Mal-B2 / 34598	FlyBaseID:	FBgn0032382	Length:	583	Species:	Drosophila melanogaster

Alignment Length:	479	Identity:	92/479 - (19%)
Similarity:	162/479 - (33%)	Gaps:	161/479 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 FLGPNGYAGVQVSPVNENAVKDSRPWWERYQPISYK-LETRSGNEEQFASMVKRCNAVGVRTYVD 112
            :|...|.....:||:.::.:.|.     .|....|| ::...|..:.|..::.....:|::..:|
  Fly    68 YLADTGITATWLSPIFQSPMIDF-----GYDISDYKAIQPEYGTMQDFEELIDTAFELGIKVVLD 127

  Fly   113 VVFNHMAAD---------------------GGTYGTGGSTASPSSKSYPGVPYSSLDFNPTCAIS 156
            .|.||.:..                     .|.....|:...|:  ::|.|.|.|        ..
  Fly   128 FVPNHSSDQHEWFKKSAAREPGYEDFYVWHDGIVQENGTRVPPN--NWPSVFYGS--------AW 182

  Fly   157 NYNDANEVRNCELVGLR--DLNQGNSYVQDKVVEFLDHL----IDLGVAGFRVDAAKHMWPADLA 215
            .:::..|..........  |||    |...|||:.:|.:    ::.||||||:||..|:: .|.:
  Fly   183 EWHEGREQYYLHQFTKEQPDLN----YRNPKVVQAMDDVLLFWLNKGVAGFRIDAVNHLF-EDES 242

  Fly   216 VIYGRLKNLNTD---HGFASGSKAYIVQEVIDM------------------GGEAISKSEYTGLG 259
            :....|....||   :.:.....:..:.||::|                  ....:....|.||.
  Fly   243 LKDEPLSGKTTDSLSYDYTKHIYSRDLPEVLEMIHHWRQLLDDFSAKHPERPTRIMMTEAYAGLT 307

  Fly   260 AITEFRHSDSIGKVFRG----------------KDQLQYLTNWGTAWGFAASDRSLVFVDNHDNQ 308
            .:.:: :.||.|  .||                .|...|:.|         .::.|:::     .
  Fly   308 QLADY-YEDSNG--VRGSHLPFNFHFITDVKGDSDARDYVYN---------VEKWLIYM-----P 355

  Fly   309 RGHGA----GGADVLTYKVPKQYKMASAFMLAHPFGTPRVMSSFSFTDTDQGPPTTDGHNI---- 365
            |||.|    |..|                       .|||.|.|       ||.:.|..|:
  Fly   356 RGHAANWVMGNHD-----------------------NPRVASRF-------GPASVDAMNMLLLT 390

  Fly   366 ---ASPIFNSDNSCSGGWVCEHR---WRQIYNMVAFRNT-------VGLDEIQN--WWDNGSNQI 415
               .:..:|.:..   |.| ::|   |.:..:..| ||.       |..|.::.  .|:|.:| .
  Fly   391 LPGVAVTYNGEEL---GMV-DYRELSWEETVDPPA-RNVGEKLYQEVSRDPVRTPFQWNNETN-A 449

  Fly   416 SFSRGSRGFVAFNNDNYDLNSSLQ 439
            .||..::.::..:.:..:||...|
  Fly   450 GFSTAAKTWLPVHPNYLELNLEAQ 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Amy-p	NP_001286518.1	AmyAc_bac_euk_AmyA	28..399	CDD:200456	82/435 (19%)
		Alpha-amylase	54..342	CDD:278554	64/356 (18%)
		Aamy_C	405..493	CDD:214749	8/37 (22%)
Mal-B2	NP_001188791.2	AmyAc_maltase	33..502	CDD:200467	92/479 (19%)
Mal-B2	NP_001188791.2	Malt_amylase_C	510..>541	CDD:351862
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45443612
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740