Protein Alignment Amy-p and Amy2a2

DIOPT Version :10

• Sequence 1: NP_536346.1
• Gene: Amy-p / 47764
• FlyBaseID: FBgn0000079
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001153624.1
• Gene: Amy2a2 / 100043688
• MGIID: 3711220
• Length: 508
• Species: Mus musculus
• Alignment Length: 510
• Identity: 281/510 - (55%)
• Similarity: 353/510 - (69%)
• Gaps: 23/510 - (4%)

  Fly     5 KSIVCLALLAVANAQFDTNYASGRSGMVHLFEWKWDDIAAECENFLGPNGYAGVQVSPVNENAV- 68
            |.::.|:|:....||:|.:.:.||:.:||||||:|.|||.|||.:|.|.|:.||||||.|||.|
Mouse     2 KFVLLLSLIGFCWAQYDPHTSDGRTAIVHLFEWRWVDIAKECERYLAPKGFGGVQVSPPNENVVV 66

  Fly    69 -KDSRPWWERYQPISYKLETRSGNEEQFASMVKRCNAVGVRTYVDVVFNHMAADG---GTYGTGG 129
             ..||||||||||||||:.||||||::|..||.|||.||||.|||.|.|||...|   ||..|.|
Mouse    67 HNPSRPWWERYQPISYKICTRSGNEDEFRDMVTRCNNVGVRIYVDAVINHMCGAGNPAGTSSTCG 131

  Fly   130 STASPSSKSYPGVPYSSLDFNPT-C--AISNYNDANEVRNCELVGLRDLNQGNSYVQDKVVEFLD 191
            |..:|:::.:|.||||:.|||.. |  .|.|||||.:||||.|.||.||.....||:.||.::::
Mouse   132 SYLNPNNREFPAVPYSAWDFNDNKCNGEIDNYNDAYQVRNCRLTGLLDLALEKDYVRTKVADYMN 196

  Fly   192 HLIDLGVAGFRVDAAKHMWPADLAVIYGRLKNLNTDHGFASGSKAYIVQEVIDMGGEAISKSEYT 256
            ||||:||||||:||||||||.|:..:..:|.|||| ..|:.||:.:|.|||||:|||||..|||.
Mouse   197 HLIDIGVAGFRLDAAKHMWPGDIKAVLDKLHNLNT-KWFSQGSRPFIFQEVIDLGGEAIKGSEYF 260

  Fly   257 GLGAITEFRHSDSIGKVFR--GKDQLQYLTNWGTAWGFAASDRSLVFVDNHDNQRGHGAGGADVL 319
            |.|.:|||::...:|.|.|  ..:::.||.|||..||...|||:|||||||||||||||||:.:|
Mouse   261 GNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGLVPSDRALVFVDNHDNQRGHGAGGSSIL 325

  Fly   320 TYKVPKQYKMASAFMLAHPFGTPRVMSSFSFTDTDQ---------GPPTTDGHNIASPI-FNSDN 374
            |:...:.||||..||||||:|..|||||:.:....|         |||..:|  :...: .|:|.
Mouse   326 TFWDARMYKMAVGFMLAHPYGFTRVMSSYRWNRNFQNGKDQNDWIGPPNNNG--VTKEVTINADT 388

  Fly   375 SCSGGWVCEHRWRQIYNMVAFRNTVGLDEIQNWWDNGSNQISFSRGSRGFVAFNNDNYDLNSSLQ 439
            :|...||||||||||.|||||||.|......|||||.|||::||||:|||:.||||::.|:::||
Mouse   389 TCGNDWVCEHRWRQIRNMVAFRNVVNGQPFSNWWDNNSNQVAFSRGNRGFIVFNNDDWALSATLQ 453

  Fly   440 TGLPAGTYCDVISGSKSGSSCTGKTVTVGSDGRASIYIGSSEDDGVLAIHVNAKL 494
            ||||||||||||||.|...:|||..|.|||||:|...|.:|.:|..:|||.::||
Mouse   454 TGLPAGTYCDVISGDKVDGNCTGLRVNVGSDGKAHFSISNSAEDPFIAIHADSKL 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Amy-p	NP_536346.1	AmyAc_bac_euk_AmyA	28..399	CDD:200456	218/390 (56%)
		Aamy_C	405..493	CDD:214749	53/87 (61%)
Amy2a2	NP_001153624.1	AmyAc_bac_euk_AmyA	25..413	CDD:200456	218/390 (56%)
		Aamy_C	420..507	CDD:214749	53/86 (62%)