Protein Alignment Abd-B and NKX2-4

DIOPT Version :10

• Sequence 1: NP_524896.2
• Gene: Abd-B / 47763
• FlyBaseID: FBgn0000015
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_149416.1
• Gene: NKX2-4 / 644524
• HGNCID: 7837
• Length: 354
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 83/312 - (26%)
• Similarity: 118/312 - (37%)
• Gaps: 87/312 - (27%)

  Fly   168 PQQQTPNSVASGASSNLQQQQQQQNAAVAPGQTQIVAPTTASVS----PSSVSSQKEDINMSIQL 228
            |:..||.|| |...|.:::..::.:.|:......:.||..|:.:    |...|||...:   ..:
Human     5 PKHTTPFSV-SDILSPIEETYKKFSGAMDGAPPGLGAPLGAAAAYRAPPPGPSSQAATV---AGM 65

  Fly   229 APLHIPAIRAGPGFETDTSAAVKRHTAHWAYNDEGFNQHYGSGYYDRKHMFAYPYPETQFPVGQY 293
            .|.|   ..||.......:||.....|...|                 ||   |...:|||.|
Human    66 QPSH---AMAGHNAAAAAAAAAAAAAAAATY-----------------HM---PPGVSQFPHG-- 105

  Fly   294 WGPNYRPDQTTSAAAAAAYMNEAERHVSAAARQSVEGTSTSSYEPPTYSSPGGLRG--------- 349
                          |..:|.|               |...:..|.|.|:.  |:||
Human   106 --------------AMGSYCN---------------GGLGNMGELPAYTD--GMRGGAATGWYGA 139

  Fly   350 YPSENYSS----SGASGGLSVGAVGPCTP--------NPGLHEWTGQVSVRKKRKP-YSKFQTLE 401
            .|...|||    .|.|.|::|..:|..|.        .| ||......:.|:||:. :|:.|..|
Human   140 NPDPRYSSISRFMGPSAGVNVAGMGSLTGIADAAKSLGP-LHAAAAAAAPRRKRRVLFSQAQVYE 203

  Fly   402 LEKEFLFNAYVSKQKRWELARNLQLTERQVKIWFQNRRMKNKKNSQRQANQQ 453
            ||:.|....|:|..:|..||..:.||..||||||||.|.|.|:.::.:|.||
Human   204 LERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQ 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abd-B	NP_524896.2	Homeodomain	388..444	CDD:459649	26/56 (46%)
NKX2-4	NP_149416.1	Homeodomain	190..246	CDD:459649	25/55 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	246..329		3/10 (30%)