DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Abd-B and hoxc11b

DIOPT Version :9

Sequence 1:	NP_001303472.1	Gene:	Abd-B / 47763	FlyBaseID:	FBgn0000015	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	XP_009298848.1	Gene:	hoxc11b / 570925	ZFINID:	ZDB-GENE-000822-3	Length:	306	Species:	Danio rerio

Alignment Length:	353	Identity:	96/353 - (27%)
Similarity:	139/353 - (39%)	Gaps:	122/353 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   174 NSVASGASSNLQQQQQQQNAAV----APGQTQIVAPTTASVSP-SSVSS-----QKEDINMSIQL 228
            |||..|   |...|.:::..:.    |...:.:..|:|..|.. |:|||     |...|..|...
Zfish     3 NSVNIG---NFCSQSRKERTSEFGERASCASNLYLPSTYYVPEFSTVSSFLPQAQSRQITYSYST 64

  Fly   229 APLHIPAIRAGPGFETDTSAAVKRH--------------------------TAHWAYNDEGFNQH 267
            ....:|.:|..| ||.:.|.  |.|                          |.....|:..:|.|
Zfish    65 NFTQVPQVRDLP-FELNPSG--KWHHRGNYSSCYAEEDLVHRDCLPPSATMTEMLMKNENVYNHH 126

  Fly   268 Y--------GSGYYDRKHMFAYPYPETQFPVGQYWGPNYRP-------DQTTSAAAAAAYMN--- 314
            :        |:|:|.              .:|:   .|..|       |...|.|...:..|
Zfish   127 HYHPAINHPGTGFYS--------------SIGK---TNVLPQSFDRFLDCAQSGADGGSEGNCLQ 174

  Fly   315 -------EAERHVSAAARQSVEG---------TSTSSYEPPTYSSPGGLRGYPSENYSSSGASGG 363
                   |:...||:..|.:.:|         |::.|:|..:        |..::|.:.||.|
Zfish   175 KGSSGKPESASQVSSVLRSTADGEKELECEKNTTSGSFETSS--------GTKNDNQTKSGHS-- 229

  Fly   364 LSVGAVGPCTPNPGLHEWTGQVSVRKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTE 428
                    .||.           :||||.||:|||..|||:||.||.|::|:||.:|:|.|.||:
Zfish   230 --------TTPR-----------MRKKRCPYTKFQIRELEREFFFNVYINKEKRLQLSRILNLTD 275

  Fly   429 RQVKIWFQNRRMKNKKNSQRQANQQNNN 456
            |||||||||||||.||.|:.:.:..:.|
Zfish   276 RQVKIWFQNRRMKEKKLSRDRLHYFSGN 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Abd-B	NP_001303472.1	Homeobox	390..443	CDD:278475	36/52 (69%)
hoxc11b	XP_009298848.1	DUF3528	41..180	CDD:288866	29/158 (18%)
hoxc11b	XP_009298848.1	Homeobox	237..290	CDD:278475	36/52 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm24582
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.000