Protein Alignment Abd-B and MSX2

DIOPT Version :10

• Sequence 1: NP_524896.2
• Gene: Abd-B / 47763
• FlyBaseID: FBgn0000015
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_002440.2
• Gene: MSX2 / 4488
• HGNCID: 7392
• Length: 267
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 71/283 - (25%)
• Similarity: 99/283 - (34%)
• Gaps: 98/283 - (34%)

  Fly   176 VASGASSN-LQQQQQQQNAAVA-----PGQTQIVAP---TTASVSPSSVSSQKEDINMSIQLAPL 231
            :||.:..| |....::..|.||     ||..:..|.   ...|..|.||.:...|.....:.:||
Human     1 MASPSKGNDLFSPDEEGPAVVAGPGPGPGGAEGAAEERRVKVSSLPFSVEALMSDKKPPKEASPL 65

  Fly   232 HIPAIRAGPGFETDTSAAVKRHTAHWAYNDEGFNQHYGSGYYDRKHMFAYPYPETQFPVGQYWGP 296
              ||..|..| .|.....:..|.|..|::.                                 ||
Human    66 --PAESASAG-ATLRPLLLSGHGAREAHSP---------------------------------GP 94

  Fly   297 NYRPDQTTSAAA-----AAAYMNEAERHVSAAARQSVEGTSTSSYEPPTYSSPGGLRGYPSENYS 356
            ..:|.:|.|..:     .||:|.|..|:                ..||.:.||
Human    95 LVKPFETASVKSENSEDGAAWMQEPGRY----------------SPPPRHMSP------------ 131

  Fly   357 SSGASGGLSVGAVGPCTPNPGLHEWTGQVSVRKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELA 421
                         ..||...  |:     :.||.|.|::..|.|.||::|....|:|..:|.|.:
Human   132 -------------TTCTLRK--HK-----TNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFS 176

  Fly   422 RNLQLTERQVKIWFQNRRMKNKK 444
            .:|.|||.||||||||||.|.|:
Human   177 SSLNLTETQVKIWFQNRRAKAKR 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abd-B	NP_524896.2	Homeodomain	388..444	CDD:459649	28/55 (51%)
MSX2	NP_002440.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71		19/71 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..147		12/78 (15%)
		Homeodomain	143..199	CDD:459649	28/55 (51%)