Protein Alignment Abd-B and zfh2

DIOPT Version :10

• Sequence 1: NP_524896.2
• Gene: Abd-B / 47763
• FlyBaseID: FBgn0000015
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_524623.2
• Gene: zfh2 / 43795
• FlyBaseID: FBgn0004607
• Length: 3005
• Species: Drosophila melanogaster
• Alignment Length: 647
• Identity: 132/647 - (20%)
• Similarity: 203/647 - (31%)
• Gaps: 221/647 - (34%)

  Fly     6 LQQQQQQQQQQEQQHLQEQQQHLQQLHHHAHHHLPQPLHTTSHHHSAHPHLQQQQQQQQHAVVAS 70
            |:.:.:|:.:|.:...|:::|..:...|.:...:..|        ||:..|...:...:..|...
  Fly   233 LEPENKQETEQNRLLNQDREQEPESDQHTSSSKMAAP--------SAYIPLSSPKVAGKLTVKFG 289

  Fly    71 SPSSVLQQQQQQSTPTTHSTP----------------------THAVMYEDPP------------ 101
            |.:|...:....|..::.|:|                      ||.....:||
  Fly   290 SLNSATAKTNNLSKVSSTSSPPSTYASGEVLSPSTDNISNHKSTHCNQETEPPSSSSSEVEMKIG 354

  Fly   102 -----------PVPLVA-VQQQHLP-----APQQQ-----------------------QQLQQQQ 126
                       .||... :|.||:.     .||..                       :.||||.
  Fly   355 SMSTSPQTNDSDVPCSGFLQMQHMTTGGAYTPQVSSFHASLAALAANESNDNRVKLITEFLQQQL 419

  Fly   127 QQQQQQLATTPVAG--ALSPAQTPTGPSAQQQQHLTSP---HH---QQLPQ-------QQTP--- 173
            ||.|..|..:|...  .|:.....|......||...||   ||   |.|||       ||||
  Fly   420 QQHQSSLFPSPCPDHPDLNGVDCKTCELLDIQQRSKSPSSSHHQFSQSLPQLQIQSQPQQTPHRS 484

  Fly   174 ---NSVASGASSNLQQQQQQQNAAVAPGQTQIVAPTTASVSPSS--VSSQKEDIN---MSIQLAP 230
               ||||               ..|:|..:.:.:...||.:.||  :.:..|.||   ..:..|.
  Fly   485 PCSNSVA---------------LPVSPSASSVASVGNASTATSSFTIGACSEHINGRPQGVDCAR 534

  Fly   231 ----LHIPAIRAGPGFETDTSA-AVKRHTAHWAYN-DEGFNQHYGSGYYDRKHMFAYPYPETQFP 289
                |:...:.:|....|..|. .:|....:|.|. .|....|....:.|.:....|.....|.|
  Fly   535 CEMLLNSARLNSGVQMSTRNSCKTLKCPQCNWHYKYQETLEIHMREKHPDGESACGYCLAGQQHP 599

  Fly   290 ---VGQYWGPNYRPDQ-------TTSAAAAAAYM------------NEAERHVSAAARQSVEGTS 332
               .|:.:...|:|.:       ||:....:.:|            |.::..|:|||..:|.|..
  Fly   600 RLARGESYSCGYKPYRCEICNYSTTTKGNLSIHMQSDKHLNNMQELNSSQNMVAAAAAAAVTGKL 664

  Fly   333 TSSYEPPTYSSPGGLRGYPSENYSSSGASGGLSVGAV----GPCTP----------NPGLHEWTG 383
            ..|     .|||......||.:.|.:|:.....||..    |..||          |.|.:  |.
  Fly   665 LLS-----SSSPQVTAACPSNSGSGAGSGSSNIVGGTASLSGNATPSVTGANSSNANAGSN--TN 722

  Fly   384 QVSVRKK---RKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVKIWFQNRRMKNKKN 445
            ....:.|   |.....:.|                   .:||||::            .|.::|:
  Fly   723 NAGTKPKPSFRCDICSYDT-------------------SVARNLRI------------HMTSEKH 756

  Fly   446 SQRQANQQNNNNNSSSNHNHAQATQQ--------HHSGHHL------NLSLNMGHHAAKMHQ 493
            :...|..|||..:..: .|..|..||        |.||..:      :|:.|.......:||
  Fly   757 THNMAVLQNNIKHIQA-FNFLQQQQQSGTGNIASHSSGSFMPEVALADLAYNQALMIQLLHQ 817

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abd-B	NP_524896.2	Homeodomain	388..444	CDD:459649	8/58 (14%)
zfh2	NP_524623.2	C2H2 Zn finger	561..581	CDD:275368	4/19 (21%)
		C2H2 Zn finger	616..633	CDD:275368	2/16 (13%)
		C2H2 Zn finger	1515..1542	CDD:275371
		C2H2 Zn finger	1543..1564	CDD:275371
		Homeodomain	1798..1857	CDD:459649
		Homeodomain	2155..2211	CDD:459649
		Homeodomain	2761..2817	CDD:459649