Protein Alignment Abd-B and NANOGP8

DIOPT Version :10

• Sequence 1: NP_524896.2
• Gene: Abd-B / 47763
• FlyBaseID: FBgn0000015
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_001342210.1
• Gene: NANOGP8 / 388112
• HGNCID: 23106
• Length: 305
• Species: Homo sapiens
• Alignment Length: 146
• Identity: 42/146 - (28%)
• Similarity: 61/146 - (41%)
• Gaps: 23/146 - (15%)

  Fly   338 PPTYSSPGGLRGYPSENYSSSGASGGLSVGAVGPCTPNPGLHEWTGQVSVRKKRKPYSKFQTLEL 402
            |.:.:||.|.:...:||          ||.......|          |..:|.|..:|..|...|
Human    66 PDSSTSPKGKQPTSAEN----------SVAKKEDKVP----------VKKQKTRTVFSSTQLCVL 110

  Fly   403 EKEFLFNAYVSKQKRWELARNLQLTERQVKIWFQNRRMKNKKNSQRQANQQNNNNNSSSNHNHAQ 467
            ...|....|:|.|:..||:..|.|:.:|||.||||:|||:|:   .|.|....|:|..:....|.
Human   111 NDRFQRQKYLSLQQMQELSNILNLSYKQVKTWFQNQRMKSKR---WQKNNWPKNSNGVTQKASAP 172

  Fly   468 ATQQHHSGHHLNLSLN 483
            .....:|.:|....:|
Human   173 TYPSLYSSYHQGCLVN 188

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abd-B	NP_524896.2	Homeodomain	388..444	CDD:459649	23/55 (42%)
NANOGP8	NP_001342210.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..96		10/49 (20%)
		Homeodomain	97..152	CDD:459649	23/54 (43%)
		8 X repeats starting with a Trp in each unit	196..240
		Sufficient for transactivation activity. /evidence=ECO:0000250	196..240
		Sufficient for strong transactivation activity. /evidence=ECO:0000250	241..305