Protein Alignment Abd-B and HOXD13

DIOPT Version :9

• Sequence 1: NP_001303472.1
• Gene: Abd-B / 47763
• FlyBaseID: FBgn0000015
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_000514.2
• Gene: HOXD13 / 3239
• HGNCID: 5136
• Length: 343
• Species: Homo sapiens
• Alignment Length: 348
• Identity: 91/348 - (26%)
• Similarity: 136/348 - (39%)
• Gaps: 80/348 - (22%)

  Fly   139 AGALSPAQTPTGPSAQQQQHLTSPHHQQLPQQQTPNSVASGASSNLQQQQQQQNAAVAPGQTQIV 203
            |.:.|.:......|.|.:..|::|             |.:|..|..........||.|...:...
Human    24 ASSSSSSVAAAAASGQCRGFLSAP-------------VFAGTHSGRAAAAAAAAAAAAAAASGFA 75

  Fly   204 APTTASVSPSSVSSQKEDINMSIQLAPLHIPAIRAGPGFETDTSAAVKRHTAHWAYNDEGFNQHY 268
            .|.|:..:.||.||.    :.::..|....|..:..|. .|..:||....:|...    |:..|:
Human    76 YPGTSERTGSSSSSS----SSAVVAARPEAPPAKECPA-PTPAAAAAAPPSAPAL----GYGYHF 131

  Fly   269 GSGYY----------DRKHMFAYPYPET-QFPVGQYWGPNYRPDQTTSAAAAAAYMNEAERHVSA 322
            |:|||          .:..:.:.|:... .|||.:|.       ..:..|:::...||    |.|
Human   132 GNGYYSCRMSHGVGLQQNALKSSPHASLGGFPVEKYM-------DVSGLASSSVPANE----VPA 185

  Fly   323 AARQSVEGTSTSSYEPPTYSSPGGL-------RGYP-------SENYSSSGASGGLSVGAVGPCT 373
            .|:   |.:....|..|....||.:       .|.|       .|.|.|...:.|.:....  ||
Human   186 RAK---EVSFYQGYTSPYQHVPGYIDMVSTFGSGEPRHEAYISMEGYQSWTLANGWNSQVY--CT 245

  Fly   374 PN--PGLHEW----TGQVSV-----------RKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELA 421
            .:  .|.|.|    .|.|::           ||||.||:|.|..|||.|:..|.:::|.||..::
Human   246 KDQPQGSHFWKSSFPGDVALNQPDMCVYRRGRKKRVPYTKLQLKELENEYAINKFINKDKRRRIS 310

  Fly   422 RNLQLTERQVKIWFQNRRMKNKK 444
            ....|:||||.|||||||:|:||
Human   311 AATNLSERQVTIWFQNRRVKDKK 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abd-B	NP_001303472.1	Homeobox	390..443	CDD:278475	27/52 (52%)
HOXD13	NP_000514.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28		1/3 (33%)
		HoxA13_N	39..174	CDD:289085	33/163 (20%)
		polyalanine repeat	57..71		3/13 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	78..115		9/41 (22%)
		homeodomain	277..333	CDD:238039	29/55 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0487
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.900