Protein Alignment Abd-B and HOXD12

DIOPT Version :10

• Sequence 1: NP_524896.2
• Gene: Abd-B / 47763
• FlyBaseID: FBgn0000015
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_067016.3
• Gene: HOXD12 / 3238
• HGNCID: 5135
• Length: 270
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 83/292 - (28%)
• Similarity: 121/292 - (41%)
• Gaps: 71/292 - (24%)

  Fly   179 GASSNLQQQQQQQNAAVAPGQTQIVAPTTASVSPSSVSSQKEDINMSIQLAPLHIPAIRAGPGFE 243
            |:..|||.......:.:.|...|:.|                       |.|:..|. .|.|...
Human    13 GSLLNLQSPDSFYFSNLRPNGGQLAA-----------------------LPPISYPR-GALPWAA 53

  Fly   244 TDTSAAVKRHTAHWAYNDEGFNQHY--GSGYYDRKHMFAYPYPETQFPVGQYWG----------- 295
            |..|.|..:.....|:.  ||:|.|  |||....:...|...||.|   .:::.
Human    54 TPASCAPAQPAGATAFG--GFSQPYLAGSGPLGLQPPTAKDGPEEQ---AKFYAPEAAAGPEERG 113

  Fly   296 ---PNYRPDQTTSAAAAAAYMNEAERHVSAAARQSVEGTSTSSYEPPTYSSPGGLRGYPSENYSS 357
               |::.|:.:.:.|.||.   :|.::..|...::..|::|.            |:|.|......
Human   114 RTRPSFAPESSLAPAVAAL---KAAKYDYAGVGRATPGSTTL------------LQGAPCAPGFK 163

  Fly   358 SGASG----GLSVGAVG------PCTPNPGLHEWTGQVSVRKKRKPYSKFQTLELEKEFLFNAYV 412
            ....|    .::|.|.|      |..|: ||.........|||||||:|.|..|||.|||.|.::
Human   164 DDTKGPLNLNMTVQAAGVASCLRPSLPD-GLPWGAAPGRARKKRKPYTKQQIAELENEFLVNEFI 227

  Fly   413 SKQKRWELARNLQLTERQVKIWFQNRRMKNKK 444
            ::|||.||:..|.|:::||||||||||||.|:
Human   228 NRQKRKELSNRLNLSDQQVKIWFQNRRMKKKR 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abd-B	NP_524896.2	Homeodomain	388..444	CDD:459649	35/55 (64%)
HOXD12	NP_067016.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	102..122		1/19 (5%)
		Homeodomain	203..259	CDD:459649	35/55 (64%)