Protein Alignment Abd-B and HOXD1

DIOPT Version :10

• Sequence 1: NP_524896.2
• Gene: Abd-B / 47763
• FlyBaseID: FBgn0000015
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_078777.1
• Gene: HOXD1 / 3231
• HGNCID: 5132
• Length: 328
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 79/292 - (27%)
• Similarity: 102/292 - (34%)
• Gaps: 96/292 - (32%)

  Fly   193 AAVAPGQTQIVAPTTASVSPSSVSSQKEDINMSIQLAPLHIPAIRA----------GPGFETDTS 247
            ||..|..:...||...||.|.: :.|.....:.....|...||..|          ||.:  |..
Human    57 AAARPSPSPPAAPARPSVPPPA-APQYAQCTLEGAYEPGAAPAAAAGGADYGFLGSGPAY--DFP 118

  Fly   248 AAVKRHTAHWAYNDEGFNQHYG-------------SGYYDRKHMFAYPYPETQFPVGQYWGPNYR 299
            ..:.|     |.:|.|.:.||.             ||..|.. .|..|.|   ||
Human   119 GVLGR-----AADDGGSHVHYATSAVFSGGGSFLLSGQVDYA-AFGEPGP---FP---------- 164

  Fly   300 PDQTTSAAAAAAYMNEAERHVSAAARQSVEGTSTSSYEPPTYS---SPGGLRGYPS--------- 352
                      |.....|:.|..|        ..|:|..|.||.   ||..  |.|:
Human   165 ----------ACLKASADGHPGA--------FQTASPAPGTYPKSVSPAS--GLPAAFSTFEWMK 209

  Fly   353 --ENYSSSGASGGLSVGAVGPCTPNPGLHEWTGQVSVRKKRKPYSKFQTLELEKEFLFNAYVSKQ 415
              .|.|..|     .:...|..:|:..:            |..:|..|..||||||.||.|:::.
Human   210 VKRNASKKG-----KLAEYGAASPSSAI------------RTNFSTKQLTELEKEFHFNKYLTRA 257

  Fly   416 KRWELARNLQLTERQVKIWFQNRRMKNKKNSQ 447
            :|.|:|..|.|.:.||||||||||||.||..:
Human   258 RRIEIANCLHLNDTQVKIWFQNRRMKQKKRER 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abd-B	NP_524896.2	Homeodomain	388..444	CDD:459649	29/55 (53%)
HOXD1	NP_078777.1	Antp-type hexapeptide	204..209		0/4 (0%)
		Homeodomain	233..286	CDD:459649	29/52 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..328