Protein Alignment Abd-B and HOXB5

DIOPT Version :10

• Sequence 1: NP_524896.2
• Gene: Abd-B / 47763
• FlyBaseID: FBgn0000015
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_002138.1
• Gene: HOXB5 / 3215
• HGNCID: 5116
• Length: 269
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 69/246 - (28%)
• Similarity: 105/246 - (42%)
• Gaps: 83/246 - (33%)

  Fly   253 HTAHWAYNDEGF----------NQHYGS-GYYDRKHMFAYPYPETQFPVGQYWGPNYR------- 299
            ||..:.||..|.          :.|:|: |...|    |:|.|..:        |.:|
Human    41 HTGSYGYNYNGMDLSVNRSSASSSHFGAVGESSR----AFPAPAQE--------PRFRQAASSCS 93

  Fly   300 ------------------------PDQTTSAAAAAAYMNEAERHVSAAARQSVEGTSTSSYEPPT 340
                                    .||.|||:::|   |..|...::|:.:..|..|       .
Human    94 LSSPESLPCTNGDSHGAKPSASSPSDQATSASSSA---NFTEIDEASASSEPEEAAS-------Q 148

  Fly   341 YSSPGGLRGYPSENYSSSGASGGLSVGAVGPCTPNPGLHEWTGQVSV---------RKKRKPYSK 396
            .|||...|..|....:|:.|..|          ..|.:..|..::.:         ::.|..|::
Human   149 LSSPSLARAQPEPMATSTAAPEG----------QTPQIFPWMRKLHISHDMTGPDGKRARTAYTR 203

  Fly   397 FQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVKIWFQNRRMKNKKNSQ 447
            :|||||||||.||.|:::::|.|:|..|.|:|||:||||||||||.||:::
Human   204 YQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abd-B	NP_524896.2	Homeodomain	388..444	CDD:459649	32/55 (58%)
HOXB5	NP_002138.1	PRK07003	<67..>171	CDD:235906	26/125 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..173		23/123 (19%)
		Antp-type hexapeptide	176..181		1/4 (25%)
		Homeodomain	195..251	CDD:459649	32/55 (58%)