Protein Alignment Abd-B and HOXB3

DIOPT Version :10

• Sequence 1: NP_524896.2
• Gene: Abd-B / 47763
• FlyBaseID: FBgn0000015
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: XP_016880049.1
• Gene: HOXB3 / 3213
• HGNCID: 5114
• Length: 578
• Species: Homo sapiens
• Alignment Length: 375
• Identity: 90/375 - (24%)
• Similarity: 133/375 - (35%)
• Gaps: 107/375 - (28%)

  Fly   140 GALSPAQ-----------TPTGPS--AQQQQHLTSPHHQQLPQQQTPNSVASGASSNLQQQQQQQ 191
            |.||||.           .|..||  |:...||...:.:.....|:..:.|..|.|     ::..
Human   158 GDLSPAARSGARCEYILCLPVLPSSVAKAATHLEGDYQRSACSLQSLGNAAPHAKS-----KELN 217

  Fly   192 NAAVAPGQTQIVAPTTASVSPSSVSSQKEDINMSIQLAPLHIPAIRAGPGFETDTSAAVKRHTAH 256
            .:.:.||    :||...|..|.|                   |...|.|     |||.
Human   218 GSCMRPG----LAPEPLSAPPGS-------------------PPPSAAP-----TSAT------- 247

  Fly   257 WAYNDEGFNQHYGSGYYDRKHMFAYPYPETQFPVGQYWGPNYRPDQTTSAAAAAAYMNEAERHVS 321
                   .|...|.|            |....|      |...|...::..          :.:.
Human   248 -------SNSSNGGG------------PSKSGP------PKCGPGTNSTLT----------KQIF 277

  Fly   322 AAARQSVEGTSTSSYEPPTYSSPGGLRGYPSENYSSSGASGGLSVGAVGPCTPNPGLHEWTGQVS 386
            ...::|.:.:...:..|.|....|| .|.......|.|:.||...|..|..:|       .|..:
Human   278 PWMKESRQTSKLKNNSPGTAEGCGG-GGGGGGGGGSGGSGGGGGGGGGGDKSP-------PGSAA 334

  Fly   387 VRKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVKIWFQNRRMKNKKNSQRQ-- 449
            .::.|..|:..|.:||||||.||.|:.:.:|.|:|..|.|:|||:||||||||||.||:.:.:
Human   335 SKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAKGL 399

  Fly   450 ANQQNNNNNSSSNHNHAQATQQHHSGHHLNLSLNMGHHA------AKMHQ 493
            |:.....:.:.|.....|:|....:..|   |:...:.:      .|.||
Human   400 ASSSGGPSPAGSPPQPMQSTAGFMNALH---SMTPSYESPSPPAFGKAHQ 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abd-B	NP_524896.2	Homeodomain	388..444	CDD:459649	30/55 (55%)
HOXB3	XP_016880049.1	Homeodomain	336..392	CDD:459649	30/55 (55%)
		DUF4074	513..576	CDD:463833