Protein Alignment Abd-B and HOXB2

DIOPT Version :10

• Sequence 1: NP_524896.2
• Gene: Abd-B / 47763
• FlyBaseID: FBgn0000015
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_002136.1
• Gene: HOXB2 / 3212
• HGNCID: 5113
• Length: 356
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 73/282 - (25%)
• Similarity: 98/282 - (34%)
• Gaps: 124/282 - (43%)

  Fly   168 PQQQTPNSVASGASSNLQQQQQQQNAAVAPGQTQIVAPTTASVSPSSVSSQKEDINMSIQLAPLH 232
            |.:||..|:..|||: ||:.:.|:.|...|.                             |.|..
Human    48 PFEQTFPSLQPGAST-LQRPRSQKRAEDGPA-----------------------------LPPPP 82

  Fly   233 IPAIRAGPGFETDTSAAVKRHTAHWAYNDEGFNQHYGSGYYDRKHMFAYPYPETQFPVGQYWGPN 297
            .|.:.|.|                                         |.||  ||
Human    83 PPPLPAAP-----------------------------------------PAPE--FP-------- 96

  Fly   298 YRPDQTTSAAAAAAYMNEAERHVSAAARQSVEGTSTSSYEPPTYSSPGGLRGYPSENYSSSGASG 362
                          :|.|.:    :|.:.|...||.|   |...:.|....|.|::......|.|
Human    97 --------------WMKEKK----SAKKPSQSATSPS---PAASAVPASGVGSPADGLGLPEAGG 140

  Fly   363 GLSVGAVGPCTPNPGLHEWTGQVSVRKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLT 427
            |   ||                   |:.|..|:..|.|||||||.||.|:.:.:|.|:|..|.||
Human   141 G---GA-------------------RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLT 183

  Fly   428 ERQVKIWFQNRRMKNKKNSQRQ 449
            |||||:||||||||:|:.:|.:
Human   184 ERQVKVWFQNRRMKHKRQTQHR 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abd-B	NP_524896.2	Homeodomain	388..444	CDD:459649	33/55 (60%)
HOXB2	NP_002136.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	39..142		36/198 (18%)
		Antp-type hexapeptide	94..99		3/28 (11%)
		Homeodomain	144..200	CDD:459649	33/55 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	197..240		3/9 (33%)