Protein Alignment Abd-B and HOXB1

DIOPT Version :10

• Sequence 1: NP_524896.2
• Gene: Abd-B / 47763
• FlyBaseID: FBgn0000015
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_002135.2
• Gene: HOXB1 / 3211
• HGNCID: 5111
• Length: 301
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 76/284 - (26%)
• Similarity: 103/284 - (36%)
• Gaps: 93/284 - (32%)

  Fly   231 LHIPAIRAGP----------GFETDTSAAVKRHTAHWAYNDEGFNQHYGSGYYDRKHMFAYPYPE 285
            |..|....||          .|...::.||.      :|..||   .||.|...........||.
Human    10 LEYPLCNRGPSAYSAHSAPTSFPPSSAQAVD------SYASEG---RYGGGLSSPAFQQNSGYPA 65

  Fly   286 TQFP--VGQYWGPNYRPDQTTSAAAAAAYMNEAERHVSAAARQSVEGTSTSS---YEPPTYSSP- 344
            .|.|  :|..: |:..|.....||.:.:|         ..::....|.|...   :.|.:|.:.
Human    66 QQPPSTLGVPF-PSSAPSGYAPAACSPSY---------GPSQYYPLGQSEGDGGYFHPSSYGAQL 120

  Fly   345 GGLRGYPSENYSSSGASGG------------------------LSVGAVGPC-----TPNPGLHE 380
            |||    |:.|.:.||..|                        ||.....||     ||.....:
Human   121 GGL----SDGYGAGGAGPGPYPPQHPPYGNEQTASFAPAYADLLSEDKETPCPSEPNTPTARTFD 181

  Fly   381 WTGQVSVRKKRKP--------------------YSKFQTLELEKEFLFNAYVSKQKRWELARNLQ 425
            |     ::.||.|                    ::..|..||||||.||.|:|:.:|.|:|..|:
Human   182 W-----MKVKRNPPKTAKVSEPGLGSPSGLRTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLE 241

  Fly   426 LTERQVKIWFQNRRMKNKKNSQRQ 449
            |.|.||||||||||||.||..:.:
Human   242 LNETQVKIWFQNRRMKQKKREREE 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abd-B	NP_524896.2	Homeodomain	388..444	CDD:459649	32/75 (43%)
HOXB1	NP_002135.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..77		14/66 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	127..149		4/21 (19%)
		Antp-type hexapeptide	179..184		1/9 (11%)
		Homeodomain	207..260	CDD:459649	29/52 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	254..301		6/12 (50%)