Protein Alignment Abd-B and HOXA5

DIOPT Version :10

• Sequence 1: NP_524896.2
• Gene: Abd-B / 47763
• FlyBaseID: FBgn0000015
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_061975.2
• Gene: HOXA5 / 3202
• HGNCID: 5106
• Length: 270
• Species: Homo sapiens
• Alignment Length: 331
• Identity: 77/331 - (23%)
• Similarity: 123/331 - (37%)
• Gaps: 120/331 - (36%)

  Fly   148 PTGPSAQQQQHLTSPHHQQLPQQQTPNSVASGA--------------------SSNLQQQQQQQN 192
            |.||  ..|.|....|.....|.:...|:.||.                    .|..:.:....:
Human    14 PNGP--DYQLHNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSGSGHFGSGERARSYAAS 76

  Fly   193 AAVAPGQTQIVAPTTASVSPSSVSSQKEDINMSIQLAPLHIPAIRAGPGFETDTSAAVKRHTAHW 257
            |:.||.:.:...|.|::.||              |..||...|:...||.::
Human    77 ASAAPAEPRYSQPATSTHSP--------------QPDPLPCSAVAPSPGSDS------------- 114

  Fly   258 AYNDEGFNQHYGSGYYDRKHMFAYPYPETQFPVGQYWGPNYRPDQTTSAAAAAAYMNEAERHVSA 322
                     |:|                         |.|...:.:.::|.|.:      .|:|
Human   115 ---------HHG-------------------------GKNSLSNSSGASADAGS------THIS- 138

  Fly   323 AARQSVEGTSTSSYEPPTYSSPGGLRGYPSENYSSSGASGGLSVGAVGPCTP-NPGLHEWTGQVS 386
             :|:.|...|.:..:.|..|.....:..||                  |..| .|.::.|..::.
Human   139 -SREGVGTASGAEEDAPASSEQASAQSEPS------------------PAPPAQPQIYPWMRKLH 184

  Fly   387 V----------RKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVKIWFQNRRMK 441
            :          ::.|..|:::|||||||||.||.|:::::|.|:|..|.|:|||:||||||||||
Human   185 ISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMK 249

  Fly   442 NKKNSQ 447
            .||:::
Human   250 WKKDNK 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abd-B	NP_524896.2	Homeodomain	388..444	CDD:459649	32/55 (58%)
HOXA5	NP_061975.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..175		30/186 (16%)
		Antp-type hexapeptide	176..181		1/4 (25%)
		Homeodomain	196..252	CDD:459649	32/55 (58%)