Protein Alignment Abd-B and HOXA4

DIOPT Version :10

• Sequence 1: NP_524896.2
• Gene: Abd-B / 47763
• FlyBaseID: FBgn0000015
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_002132.3
• Gene: HOXA4 / 3201
• HGNCID: 5105
• Length: 320
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 82/314 - (26%)
• Similarity: 117/314 - (37%)
• Gaps: 80/314 - (25%)

  Fly   197 PGQTQIVAPTTASVSPSSVSSQKEDINMSIQLAPLHIPAI-RAGPGFETDTSAAVKRHTAHWAYN 260
            ||..|..||.|                   |..||..|.: .||.|.|...|....|.....||.
Human    40 PGYQQPPAPPT-------------------QHLPLQQPQLPHAGGGREPTASYYAPRTAREPAYP 85

  Fly   261 DEGFNQHYGSGYYDRKHMFAYPYPETQFPVGQYWGPN-YRPDQTTSAAAAAAYMNEAERHVSAAA 324
            .......:|:.             :|.:|.|...|.: .||.|              .....|.|
Human    86 AAALYPAHGAA-------------DTAYPYGYRGGASPGRPPQ--------------PEQPPAQA 123

  Fly   325 RQSVEGTSTSSYEPPTYSSPGGLRGYP---SENYSSSGASGGLSVGAVGPCTP------------ 374
            :....|...|....|....|...|..|   .....::.|:.|:..|...|..|
Human   124 KGPAHGLHASHVLQPQLPPPLQPRAVPPAAPRRCEAAPATPGVPAGGSAPACPLLLADKSPLGLK 188

  Fly   375 --NPGLHEWTGQVSV------------RKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQ 425
              .|.::.|..::.|            ::.|..|::.|.|||||||.||.|:::::|.|:|..|.
Human   189 GKEPVVYPWMKKIHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLC 253

  Fly   426 LTERQVKIWFQNRRMKNKKNSQRQANQQNNNNNSSSN---HNHAQATQQHHSGH 476
            |:||||||||||||||.||:.:....:..::|::|::   ...||....|...|
Human   254 LSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNSASASAGPPGKAQTQSPHLHPH 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abd-B	NP_524896.2	Homeodomain	388..444	CDD:459649	32/55 (58%)
HOXA4	NP_002132.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..77		15/55 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	101..168		16/80 (20%)
		Antp-type hexapeptide	194..199		1/4 (25%)
		Homeodomain	216..272	CDD:459649	32/55 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	273..320		6/35 (17%)