DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Abd-B and hoxd10a

DIOPT Version :9

Sequence 1:	NP_001303472.1	Gene:	Abd-B / 47763	FlyBaseID:	FBgn0000015	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_571241.2	Gene:	hoxd10a / 30404	ZFINID:	ZDB-GENE-990415-116	Length:	332	Species:	Danio rerio

Alignment Length:	334	Identity:	94/334 - (28%)
Similarity:	136/334 - (40%)	Gaps:	74/334 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 LSPAQTPTGPSAQQQQHLTSPHHQQLPQQQT---PNSVASGASSNLQQQQQQQNAAVAPGQTQIV 203
            |.||....|....|...:|.  |..:||..|   |:     .|..|:|...|.:....   :|.:
Zfish    51 LLPALGKRGEVNHQNMDMTV--HSYIPQTDTWADPS-----RSCRLEQPLNQMSTCTF---SQSI 105

  Fly   204 APTT---------ASVSPSSVSSQKEDINMSIQLAPLHIPAIRAGPGF--ETDTSAAVKRHTAHW 257
            ...|         |.||.|.:.:....|..|..:....||.    ||:  .:.|.|..|...
Zfish   106 KEETNCCMYSDKRAKVSSSEIPAYSSLIPESCSVDSPEIPV----PGYFRLSQTYATAKNPD--- 163

  Fly   258 AYNDEGFNQHYGSGYYDRKHMFAY--PYPETQFPVGQYWGPNYRPDQTTSAAAAAAYMNEAERHV 320
             |::|..:.:......:|....|.  |:.|.:..:..        |:.|.:::.|   ...|..|
Zfish   164 -YDNETMSPNTTLMQLNRATPKAQSTPFVEVEKKLAH--------DRDTRSSSPA---QSPEPKV 216

  Fly   321 SAAARQ--SVEGTSTSSYEPPTYSSPGGLRGYPSENYSSSGASGGLSVGAVGPCTPNPGLHEWTG 383
            |....:  |.| .|.||.|.|...........|:.|                          |..
Zfish   217 STLEEKNCSTE-ASVSSPELPHREGKESKNDTPTSN--------------------------WLT 254

  Fly   384 QVSVRKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVKIWFQNRRMKNKKNSQR 448
            ..|.||||.||:|.||||||||||||.|:::::|.|:::::.||:|||||||||||||.||.|:.
Zfish   255 AKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSRE 319

  Fly   449 QANQQNNNN 457
            ...::..:|
Zfish   320 NRIRELTSN 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Abd-B	NP_001303472.1	Homeobox	390..443	CDD:278475	35/52 (67%)
hoxd10a	NP_571241.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	194..261		18/104 (17%)
		COG5576	204..>321	CDD:227863	55/146 (38%)
		Homeobox	261..314	CDD:278475	35/52 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	92	1.000	Domainoid score	I7557
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D414477at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm24582
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45874
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.110