DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Abd-B and Hoxb8

DIOPT Version :9

Sequence 1:	NP_001303472.1	Gene:	Abd-B / 47763	FlyBaseID:	FBgn0000015	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_034591.1	Gene:	Hoxb8 / 15416	MGIID:	96189	Length:	243	Species:	Mus musculus

Alignment Length:	217	Identity:	67/217 - (30%)
Similarity:	100/217 - (46%)	Gaps:	54/217 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   286 TQFPVGQYWGPNY-----------RPDQTTSAAAAAAYMNEAERHVSAAARQSVEGTSTSSYEP- 338
            :::..|:...|||           ||......::..::.:.::      .::...|.|:.|..|
Mouse    11 SKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQ------IQEFYHGPSSLSTAPY 69

  Fly   339 -------PTYSSPGGLRGY-PSENYSSSG---------------ASGGLSVGAVG-PCTPNP-GL 378
                   ..:..||...|| |.:..|..|               |:.||...|.| ..:|:| .|
Mouse    70 QQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGEEAEGSEQSPSPTQL 134

  Fly   379 HEW---TGQVSVRKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVKIWFQNRRM 440
            ..|   ......|:.|:.||::||||||||||||.|:::::|.|::..|.|||||||||||||||
Mouse   135 FPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRM 199

  Fly   441 KNKKNSQRQANQQNNNNNSSSN 462
            |.||        :||.:...|:
Mouse   200 KWKK--------ENNKDKFPSS 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Abd-B	NP_001303472.1	Homeobox	390..443	CDD:278475	35/52 (67%)
Hoxb8	NP_034591.1	Antp-type hexapeptide	134..139		2/4 (50%)
		Homeobox	150..203	CDD:395001	35/52 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	203..243		4/19 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D414477at33208
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010