DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fkbp59 and Fkbp12

DIOPT Version :9

Sequence 1:	NP_001285784.1	Gene:	Fkbp59 / 47762	FlyBaseID:	FBgn0029174	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_523792.2	Gene:	Fkbp12 / 37214	FlyBaseID:	FBgn0013954	Length:	108	Species:	Drosophila melanogaster

Alignment Length:	104	Identity:	52/104 - (50%)
Similarity:	75/104 - (72%)	Gaps:	0/104 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 GVLKEILKEGTGTETPHSGCTVSLHYTGRLVDGTEFDSSLSRNEPFEFSLGKGNVIKAFDMGVAT 78
            ||....:..|.|:..|.:|..|::||||.|.|||:||||..||:||:|::|||.||:.:|.|||.
  Fly     2 GVQVVPIAPGDGSTYPKNGQKVTVHYTGTLDDGTKFDSSRDRNKPFKFTIGKGEVIRGWDEGVAQ 66

  Fly    79 MKLGERCFLTCAPNYAYGAAGSPPAIPPDATLIFELEML 117
            :.:|:|..|.|:|:||||:.|.|..|||::||.|::|:|
  Fly    67 LSVGQRAKLICSPDYAYGSRGHPGVIPPNSTLTFDVELL 105

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp59	NP_001285784.1	FKBP_C	25..117	CDD:278674	48/91 (53%)
		ppisom_GldI	<124..233	CDD:132555
		BamD	252..>390	CDD:276939
		TPR_12	252..329	CDD:290160
		TPR repeat	252..280	CDD:276939
		TPR repeat	252..280	CDD:276809
		TPR repeat	287..326	CDD:276939
		TPR repeat	296..326	CDD:276809
		TPR_11	299..362	CDD:290150
		TPR repeat	329..361	CDD:276939
		TPR_1	331..364	CDD:278916
		TPR repeat	331..359	CDD:276809
Fkbp12	NP_523792.2	FkpA	<2..107	CDD:223619	52/104 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452521
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D138435at6960
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100299
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.650