DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fkbp59 and zda

DIOPT Version :9

Sequence 1:	NP_001285784.1	Gene:	Fkbp59 / 47762	FlyBaseID:	FBgn0029174	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001286579.1	Gene:	zda / 37144	FlyBaseID:	FBgn0034368	Length:	397	Species:	Drosophila melanogaster

Alignment Length:	359	Identity:	83/359 - (23%)
Similarity:	156/359 - (43%)	Gaps:	71/359 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 APNYAYGAAGSPPA-IPPDATLIFELEMLGWKGEDLSPNQD----GS---IDRTILEA-SDKKRT 145
            |...|....|:||| :..|          |.|.|:....::    |:   |.|||.:| .|..|.
  Fly    27 AAEEAASGDGAPPASVSGD----------GQKAEEEDAEEECDILGNKQLIKRTIKKAPQDSFRR 81

  Fly   146 PSDGAFVKAHISGSFEGRVFEDRDVEF-----DYGEGKAIGIIDGVEIALEKMNVGETSRIKIQA 205
            |..|..|..:.:|..:.....:.::.|     ||      .:|.|:::.|..:.|||.|::.:.:
  Fly    82 PIRGELVTVNFTGKLDNGTVVENELNFQCHVGDY------EVIQGLDMVLPMLQVGEVSQVSVDS 140

  Fly   206 KYAFGA-----KGNEEFKIPPNATVEYTVKLVDCGKGLEEWKLSDEERLAEAKVY---------- 255
            ::.:|:     :|..|:.:||:|.:.|.::|:|.          ..|..|:.|.:
  Fly   141 RFGYGSLGLKKEGESEYLVPPDAHLTYEIELLDI----------KYEEFADLKSFEILRKYGTRK 195

  Fly   256 KEKGTNYFKKENWALAIKMYTKCKNIL------PTTVHTNEEVK----------KIKVATHSNIA 304
            ||:...::|:..:..||.:|.:..:.|      |.:....|:::          :.::..::|:|
  Fly   196 KERANFFYKRSEFTTAIHLYRRALDFLDNRDGDPDSEFDKEDLELSNSDTQTLLEDRLIVYNNLA 260

  Fly   305 LCHQKSNDHFEAKQECNEVLALDKNNVKALYRRGQCNLTINELEDALEDFQKVIQLEPGNKAAAN 369
            :...|...:..|.|....||....||.|||||:|:......:.:.|::..|||..|||.|:|..:
  Fly   261 MTQIKIAAYDAALQSVEHVLRCQPNNSKALYRKGRILEGKADTQGAIKLLQKVATLEPENRAVQS 325

  Fly   370 QVIICKQKLKESKNKEKKLYANMFTKLAANDKET 403
            .:.....|.:..::.||::|..|..:....::.|
  Fly   326 DLARLFIKARREEHNEKEMYQKMLGQAKKMEQNT 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp59	NP_001285784.1	FKBP_C	25..117	CDD:278674	7/27 (26%)
		ppisom_GldI	<124..233	CDD:132555	30/126 (24%)
		BamD	252..>390	CDD:276939	37/163 (23%)
		TPR_12	252..329	CDD:290160	17/102 (17%)
		TPR repeat	252..280	CDD:276939	7/37 (19%)
		TPR repeat	252..280	CDD:276809	7/37 (19%)
		TPR repeat	287..326	CDD:276939	8/48 (17%)
		TPR repeat	296..326	CDD:276809	7/29 (24%)
		TPR_11	299..362	CDD:290150	20/62 (32%)
		TPR repeat	329..361	CDD:276939	12/31 (39%)
		TPR_1	331..364	CDD:278916	13/32 (41%)
		TPR repeat	331..359	CDD:276809	10/27 (37%)
zda	NP_001286579.1	FKBP_C	80..172	CDD:278674	22/97 (23%)
		TPR_11	196..284	CDD:290150	16/87 (18%)
		TPR repeat	196..220	CDD:276809	6/23 (26%)
		TPR repeat	252..282	CDD:276809	7/29 (24%)
		TPR_11	255..318	CDD:290150	20/62 (32%)
		TPR repeat	287..313	CDD:276809	8/25 (32%)
		TPR repeat	321..349	CDD:276809	5/27 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452527
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740