DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fkbp59 and Fkbp10

DIOPT Version :9

Sequence 1:	NP_001285784.1	Gene:	Fkbp59 / 47762	FlyBaseID:	FBgn0029174	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	XP_038942330.1	Gene:	Fkbp10 / 360627	RGDID:	1549751	Length:	620	Species:	Rattus norvegicus

Alignment Length:	214	Identity:	65/214 - (30%)
Similarity:	102/214 - (47%)	Gaps:	15/214 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 SGCTVSLHYTGRLVDGTEFDSSLSRNEPFEFSLGKGNVIKAFDMGVATMKLGERCFLTCAPNYAY 95
            :|..:..||.|.|:|||.||||.|||..:...:|:|.:|...|.|:....:|||..:|..|:.||
  Rat   323 AGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYVGQGYIIPGMDQGLQGACIGERRRITVPPHLAY 387

  Fly    96 GAAGSPPAIPPDATLIFELEMLGWKGEDLSPNQDGSIDRTILEASDKKRTPSDGAFVKAHISGS- 159
            |..|:...||..|.|||::.::.:.    :|.....|............|...|.|::.|.:.|
  Rat   388 GENGTGDKIPGSAVLIFDVHVIDFH----NPADPVEIKTLFRPPESCNETAKIGDFIRYHYNCSL 448

  Fly   160 FEG-RVFEDRDV----EFDYGEGKAIGIIDGVEIALEKMNVGETSRIKIQAKYAFGAKGNEEFKI 219
            .:| |:|...|.    |...|..|   :|:|::..|:.|.|||..::.:....|.|..|..  .:
  Rat   449 LDGTRLFSSHDYEAPQEITLGANK---VIEGLDRGLQGMCVGERRQLIVPPHLAHGENGAR--GV 508

  Fly   220 PPNATVEYTVKLVDCGKGL 238
            |.:|.:.:.|:|:....||
  Rat   509 PGSAVLLFEVELISREDGL 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp59	NP_001285784.1	FKBP_C	25..117	CDD:278674	35/85 (41%)
		ppisom_GldI	<124..233	CDD:132555	28/114 (25%)
		BamD	252..>390	CDD:276939
		TPR_12	252..329	CDD:290160
		TPR repeat	252..280	CDD:276939
		TPR repeat	252..280	CDD:276809
		TPR repeat	287..326	CDD:276939
		TPR repeat	296..326	CDD:276809
		TPR_11	299..362	CDD:290150
		TPR repeat	329..361	CDD:276939
		TPR_1	331..364	CDD:278916
		TPR repeat	331..359	CDD:276809
Fkbp10	XP_038942330.1	FKBP_C	54..146	CDD:395196
		FKBP_C	166..297	CDD:395196
		FKBP_C	317..409	CDD:395196	35/85 (41%)
		FKBP_C	430..521	CDD:395196	25/95 (26%)
		EFh	544..605	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810