Protein Alignment Fkbp59 and TTC9

DIOPT Version :10

• Sequence 1: NP_524895.2
• Gene: Fkbp59 / 47762
• FlyBaseID: FBgn0029174
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_056166.1
• Gene: TTC9 / 23508
• HGNCID: 20267
• Length: 222
• Species: Homo sapiens
• Alignment Length: 217
• Identity: 44/217 - (20%)
• Similarity: 82/217 - (37%)
• Gaps: 40/217 - (18%)

  Fly   208 AFGAKGNEEFKIPPNATVEYTVKLVDC---------GKGLEEWKLSDEERLAEAKVYKEKGTNYF 263
            |.|||||..   ||.|..........|         .:|.........|.:..|..:|.:|...:
Human     7 AAGAKGNPS---PPAAGEGQRPPPPLCVPGGGGGAPARGQVGAAAEPAELIRRAHEFKSQGAQCY 68

  Fly   264 KKENWALAIKMYTKC----KNILP----------------------TTVHTNEEVKKIKVATHSN 302
            |.:.:..||..|.:.    |.:||                      .:...::.|:.|::..:::
Human    69 KDKKFREAIGKYHRALLELKGLLPPPGERERDSRPASPAGALKPGRLSEEQSKTVEAIEIDCYNS 133

  Fly   303 IALCHQKSN--DHFEAKQECNEVLALDKNNVKALYRRGQCNLTINELEDALEDFQKVIQLEPGNK 365
            :|.|..::.  ::...|:.|.:||..:..|.|||||.|.....:.:.:.||...::....:|.:.
Human   134 LAACLLQAELVNYERVKEYCLKVLKKEGENFKALYRSGVAFYHLGDYDKALYYLKEARTQQPTDT 198

  Fly   366 AAANQVIICKQKLKESKNKEKK 387
            .....:.:.:.||.....:||:
Human   199 NVIRYIQLTEMKLSRCSQREKE 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp59	NP_524895.2	FKBP_C	25..117	CDD:459735
		SlpA	147..>210	CDD:440668	1/1 (100%)
		NlpI	<245..402	CDD:443815	33/171 (19%)
		TPR repeat	252..280	CDD:276809	7/31 (23%)
		TPR repeat	296..326	CDD:276809	6/31 (19%)
		TPR repeat	331..359	CDD:276809	8/27 (30%)
TTC9	NP_056166.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..49		11/44 (25%)
		TPR 1	56..89		7/32 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	88..116		3/27 (11%)
		TPR	<124..>213	CDD:440225	19/88 (22%)
		TPR 2	125..160		7/34 (21%)
		TPR repeat	130..159	CDD:276809	6/28 (21%)
		TPR 3	161..194		9/32 (28%)
		TPR repeat	164..190	CDD:276809	8/25 (32%)