DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment betaggt-II and Fntb

DIOPT Version :9

Sequence 1:	NP_524894.1	Gene:	betaggt-II / 47757	FlyBaseID:	FBgn0028970	Length:	347	Species:	Drosophila melanogaster
Sequence 2:	NP_742031.1	Gene:	Fntb / 64511	RGDID:	620119	Length:	437	Species:	Rattus norvegicus

Alignment Length:	328	Identity:	102/328 - (31%)
Similarity:	166/328 - (50%)	Gaps:	28/328 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 LQFWKHVEYIENHGKQEDDYEYCMTEFLRMSGIYWGTTALDIMGQ-LERLERKSIIEFVKRCQCP 92
            ||..||..|::...:|..|...|: :..|....||...:|:::.: :.::....:.:|::.||.|
  Rat    73 LQREKHFHYLKRGLRQLTDAYECL-DASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSP 136

  Fly    93 NTGGFAPCEGHDPHLLYTLSAIQILC---TYDALEEIDREAVVRFVVGLQQPDGSFFGDKWGEVD 154
            : |||....|..|||..|.:|:..||   |.:|...|:||.:::::..|:||||||.....||||
  Rat   137 D-GGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYNVINREKLLQYLYSLKQPDGSFLMHVGGEVD 200

  Fly   155 TRFSFCA--VASLTLLGRMEQTIDVEKAVKFVLSCCNQTDGGFGSKPGAESHAGLIYCCVGFFSL 217
            .|.::||  |||||.:    .|.|:.:.....::.|...:||.|..||.|:|.|..:|.:....:
  Rat   201 VRSAYCAASVASLTNI----ITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVI 261

  Fly   218 THRLHLLDVDKLGWWLCERQLP-SGGLNGRPEKLPDVCYSWWVLASLTIMGRL------------ 269
            ..:...|::..|..|:..||:. .||..||..||.|.|||:|....|.::.|.
  Rat   262 LKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMS 326

  Fly   270 HWI-SSEKLQQFILSCQDTETGGFSDRTGNMPDIFHTLFGIGGLSLLGHSGLKAI--NPTLCMPQ 331
            ||: ..:.||::||.|.....||..|:.|...|.:||.:.:.|||:..|.|..|:  :..:.:|:
  Rat   327 HWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVMGVPE 391

  Fly   332 YII 334
            .::
  Rat   392 NVL 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
betaggt-II	NP_524894.1	GGTase-II	29..315	CDD:239224	98/305 (32%)
betaggt-II	NP_524894.1	PLN03201	33..340	CDD:215630	100/324 (31%)
Fntb	NP_742031.1	FTase	75..373	CDD:239223	96/303 (32%)
		PFTB 1	123..164		15/41 (37%)
		PFTB 2	174..215		20/40 (50%)
		PFTB 3	222..263		10/40 (25%)
		Farnesyl diphosphate binding	248..251		1/2 (50%)
		PFTB 4	270..312		16/41 (39%)
		Farnesyl diphosphate binding	291..294		1/2 (50%)
		Farnesyl diphosphate binding	300..303		2/2 (100%)
		PFTB 5	332..374		15/41 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1042804at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820