Protein Alignment RabGGTb and PGGT1B

DIOPT Version :10

• Sequence 1: NP_524894.1
• Gene: RabGGTb / 47757
• FlyBaseID: FBgn0028970
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: XP_011541792.1
• Gene: PGGT1B / 5229
• HGNCID: 8895
• Length: 408
• Species: Homo sapiens
• Alignment Length: 350
• Identity: 104/350 - (29%)
• Similarity: 164/350 - (46%)
• Gaps: 44/350 - (12%)

  Fly    24 GGGQKLQFW--KHVEYIENHGKQEDDYEYCMTEFLRMSGIYWGTTALDIMGQLERLERKSIIEFV 86
            |.|::|.|.  :||.:.: ...|.....|...|..|::..::..:.||::..|:.:.:..|||::
Human    13 GEGERLDFLRDRHVRFFQ-RCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWI 76

  Fly    87 KRCQ-CP-------NTGGF--------------APCEGHDPH------LLYT-LSAIQILCTYDA 122
            ...| .|       |..||              ||...| |:      :.|| ||.:.||  .|.
Human    77 YSLQVLPTEDRSNLNRCGFRGSSYLGIPFNPSKAPGTAH-PYDSGHIAMTYTGLSCLVIL--GDD 138

  Fly   123 LEEIDREAVVRFVVGLQQPDGSFFGDKWG-EVDTRFSFCAVASLTLLGRMEQTIDVEKAVKFVLS 186
            |..:::||.:..:..||..||||.....| |.|.||.:||.....:|... ..:|::||:.::..
Human   139 LSRVNKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNW-SGMDMKKAITYIRR 202

  Fly   187 CCNQTDGGFGSKPGAESHAGLIYCCVGFFSLTHRLHLL----DVDKLGWWLCERQLPSGGLNGRP 247
            ..:. |.|.....|.|||.|..:|.:....|..:|..:    :::::..|...||  ..|.:|||
Human   203 SMSY-DNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQ--QNGYHGRP 264

  Fly   248 EKLPDVCYSWWVLASLTIMGRLHWISSEKLQQFILSCQDTETGGFSDRTGNMPDIFHTLFGIGGL 312
            .|..|.|||:||.|:|.::....:.:.||.:.:|||.||...|||:....:.||..|..|||.||
Human   265 NKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGL 329

  Fly   313 SLLGHSGLKAINPTLCMPQYIIDRL 337
            ||:..||:..::|.|.:.....:||
Human   330 SLMEESGICKVHPALNVSTRTSERL 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RabGGTb	NP_524894.1	GGTase-II	29..315	CDD:239224	95/321 (30%)
PGGT1B	XP_011541792.1	GGTase-I	22..332	CDD:239225	93/317 (29%)