DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment betaggt-II and rabggtb

DIOPT Version :9

Sequence 1:	NP_524894.1	Gene:	betaggt-II / 47757	FlyBaseID:	FBgn0028970	Length:	347	Species:	Drosophila melanogaster
Sequence 2:	NP_998277.2	Gene:	rabggtb / 406386	ZFINID:	ZDB-GENE-040426-2116	Length:	331	Species:	Danio rerio

Alignment Length:	312	Identity:	203/312 - (65%)
Similarity:	251/312 - (80%)	Gaps:	3/312 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 KHVEYIENHGKQEDDYEYCMTEFLRMSGIYWGTTALDIMGQLERLERKSIIEFVKRCQCPNTGGF 97
            ||.:||..:|.::|||||.::|:|||||||||.|.:|:||||.|:.|:.||||:|.|| .:.||.
Zfish    22 KHADYIAAYGSKKDDYEYTLSEYLRMSGIYWGLTVMDLMGQLSRMNREEIIEFIKSCQ-HDCGGI 85

  Fly    98 APCEGHDPHLLYTLSAIQILCTYDALEEIDREAVVRFVVGLQQPDGSFFGDKWGEVDTRFSFCAV 162
            :...||||||||||||||||..||::..||.:.||.:|.||||.||||.||||||:|||||||||
Zfish    86 SASIGHDPHLLYTLSAIQILSLYDSVNAIDVDKVVEYVKGLQQEDGSFAGDKWGEIDTRFSFCAV 150

  Fly   163 ASLTLLGRMEQTIDVEKAVKFVLSCCNQTDGGFGSKPGAESHAGLIYCCVGFFSLTHRLHLLDVD 227
            |:|.|||::: .|:|:|||:||:||.| .|||||.:||:|||||.||||.||.|:|.:||.::.|
Zfish   151 ATLALLGKLD-VINVDKAVEFVMSCMN-FDGGFGCRPGSESHAGQIYCCTGFLSVTGQLHQVNAD 213

  Fly   228 KLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLTIMGRLHWISSEKLQQFILSCQDTETGGF 292
            .|||||||||||||||||||||||||||||||||||.|:||:|||...||:.|||:|||.|||||
Zfish   214 LLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRIHWIDKAKLRNFILACQDEETGGF 278

  Fly   293 SDRTGNMPDIFHTLFGIGGLSLLGHSGLKAINPTLCMPQYIIDRLGIKPQLL 344
            :||.|:|.|.||||||:.||||||...:|.:||..|||:.::.|:|::|.||
Zfish   279 ADRPGDMVDPFHTLFGVAGLSLLGDEQIKPVNPVFCMPEDVLQRIGLQPDLL 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
betaggt-II	NP_524894.1	GGTase-II	29..315	CDD:239224	189/281 (67%)
betaggt-II	NP_524894.1	PLN03201	33..340	CDD:215630	200/306 (65%)
rabggtb	NP_998277.2	PLN03201	14..326	CDD:215630	200/306 (65%)
rabggtb	NP_998277.2	GGTase-II	18..301	CDD:239224	189/281 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573886
Domainoid	1	1.000	68	1.000	Domainoid score	I9719
eggNOG	1	0.900	-	-		E1_COG5029
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3371
Inparanoid	1	1.050	441	1.000	Inparanoid score	I1630
OMA	1	1.010	-	-		QHG53725
OrthoDB	1	1.010	-	-		D1042804at2759
OrthoFinder	1	1.000	-	-		FOG0004681
OrthoInspector	1	1.000	-	-		oto39978
orthoMCL	1	0.900	-	-		OOG6_102449
Panther	1	1.100	-	-	LDO	PTHR11774
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R919
SonicParanoid	1	1.000	-	-		X3289
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800