Protein Alignment NFIA and nfia

DIOPT Version :10

• Sequence 1: NP_001138984.1
• Gene: NFIA / 4774
• HGNCID: 7784
• Length: 554
• Species: Homo sapiens
• Sequence 2: XP_009294512.1
• Gene: nfia / 556665
• ZFINID: ZDB-GENE-050208-501
• Length: 570
• Species: Danio rerio
• Alignment Length: 540
• Identity: 457/540 - (84%)
• Similarity: 480/540 - (88%)
• Gaps: 42/540 - (7%)

Human    55 DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQKWASR 119
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish    33 DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQKWASR 97

Human   120 LLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRLDLVMVILFKG 184
            ||||||||||||:||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish    98 LLAKLRKDIRPEFREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRLDLVMVILFKG 162

Human   185 IPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSSQSESPSQPSDADIKD 249
            ||||||||||||||||||||||||||||||||||||||||||||| |::.||:||:|||:.||||
Zfish   163 IPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVH-AEAGQSDSPNQPSEGDIKD 226

Human   250 QPENGHLGFQDSFVTSGVFSVTELVRVSQT--------------------PIAAGTGPNFSLSDL 294
            |||||||||||||||||||:|:||||||||                    ||||||||||||:||
Zfish   227 QPENGHLGFQDSFVTSGVFTVSELVRVSQTGPHIKSDTVKPQFGTPSSSAPIAAGTGPNFSLADL 291

Human   295 ESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVE 359
            :||||||||||||||.||||||:||.||:|.:|||:||||||.:|.|||||||||||:|.|||||
Zfish   292 DSSSYYSMSPGAMRRPLPSTSSSSSAKRIKCMEDEVDSPGEESYYPGQGRSPGSGSQASSWHEVE 356

Human   360 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQP 424
            ||||||||||||||||||||.||||:|..||||.||||||||||||||||||:||||||||||||
Zfish   357 PGMPSPTTLKKSEKSGFSSPVPSQTASPRTAFTHHHRPVITGPRASPHATPSSLHFPTSPIIQQP 421

Human   425 GPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPP 489
            |.||||.||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||
Zfish   422 GSYFSHHAIRYHPQETLKEFVQLVCPDSGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPP 486

Human   490 MARPVPLPVPDTKPPTTSTEGGAASPTSPT--------------------YSTPSTSPANRFVSV 534
            |||||||||||:|||:|||:||..|||||:                    |||||||||.|||||
Zfish   487 MARPVPLPVPDSKPPSTSTDGGGNSPTSPSECLTSCMTSHLMPHTTLTKAYSTPSTSPAQRFVSV 551

Human   535 GPRDPSFVNIPQQTQSWYLG 554
            |||||||||||||.| ||||
Zfish   552 GPRDPSFVNIPQQPQ-WYLG 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NFIA	NP_001138984.1	NfI_DNAbd_pre-N	54..91	CDD:463134	35/35 (100%)
		MH1	113..217	CDD:460833	102/103 (99%)
		CTF_NFI	259..546	CDD:459967	254/326 (78%)
nfia	XP_009294512.1	NfI_DNAbd_pre-N	33..69	CDD:463134	35/35 (100%)
		MH1	91..195	CDD:460833	102/103 (99%)
		CTF_NFI	236..563	CDD:459967	254/326 (78%)