Protein Alignment TTLL4A and ttll3

DIOPT Version :10

• Sequence 1: NP_723642.2
• Gene: TTLL4A / 47729
• FlyBaseID: FBgn0026147
• Length: 1071
• Species: Drosophila melanogaster
• Sequence 2: NP_001038770.1
• Gene: ttll3 / 724000
• ZFINID: ZDB-GENE-060616-182
• Length: 771
• Species: Danio rerio
• Alignment Length: 806
• Identity: 177/806 - (21%)
• Similarity: 288/806 - (35%)
• Gaps: 268/806 - (33%)

  Fly   353 SGD------TLINNNNNELKIMRKSTDQPMPRLPMTPKRAKGGTVSTKKPMPTVHRVLLYSTQSP 411
            :||      ||::....|.|:.......|:.|..:   ||: |.|..:.|.|:
Zfish    25 NGDKLRTAKTLVDKAIKEKKVFSVQGPYPVIRAGL---RAR-GWVERRLPRPS------------ 73

  Fly   412 RLGRKQQFSTQRLSVKQQSSKVLGAGDERQTVLLLEPEHKQEDHRSAIDFDRNDDFDEDDDLDNL 476
                   ||..|             ..:.:|....|.:...||       |..::.:.||:.::|
Zfish    74 -------FSQPR-------------RHDHETETTDEGDSSDED-------DLGEEVERDDEAEDL 111

  Fly   477 SNF------------------DESDTASVLSDTEDGYRAHAFKLT---------HSVDRFSSPQS 514
            .:.                  |..|..|:..:....:.|.|...|         .::..|.:...
Zfish   112 YDLMSRLVRHETPYFYWTTRRDSVDCRSLRKEQMTNHYAKAGSFTTKVGLCMHLRNLQWFDAADP 176

  Fly   515 TPSF-----LSSQSSE----DDLKNPDSLLVPSLFPYV-PPYLSFSSNTKRGPRVPPDLHRVLKW 569
            ...|     |.:|..:    ||.:.   ....||..|| ..|...|...|.|     ::|..
Zfish   177 DTFFPRCYRLGAQDEKHAFIDDFRR---TACTSLLLYVLEKYEGDSEGEKMG-----EVHNA--- 230

  Fly   570 RITNIMPKVVRLILANSGMRMLKKTNDWMGVWGKHLKSP---CFKAIRSYQKI---NHLPGSFRI 628
                          .:.|:|..:|.:....:....:.|.   |.:.:.|.:..   |:|..:..|
Zfish   231 --------------KSHGLRKTRKQHSSQRIETSVIDSALHVCQEYLNSLEHCDIDNNLETNSTI 281

  Fly   629 GRKDSCWKNLQRQMGKHSNKEFGFMPRTYIIPND-----------------LGALRRHWPKYAQR 676
            ..:.  ||              .|:...|::.::                 |..:|:..|:....
Zfish   282 SEQQ--WK--------------VFLQNYYLVVHEGINIEGCEYYLERCKCMLEQMRQVCPQMEND 330

  Fly   677 N--TKWIIKPPASARGAGIRVINRWGQ----------IPKRRPLIVQKYIERPLLINGSKFDLRL 729
            .  ..|||||.|.:||.||..:|:...          |.|....:||||||||||::.:|||:|.
Zfish   331 GICNIWIIKPGAKSRGRGIMCMNKLDDMLGLVDGDHCIMKDSKWVVQKYIERPLLVHDTKFDVRQ 395

  Fly   730 YVLVTSVNPLRVFMYHNGLARFASVKYSAKTDTLNDRCMHLTNYSINKFSSNYSKNEDVN----- 789
            :.|||..|||.|:.|.....||::..||  |.|| |..:||.|.||.|   :|..:.|.:
Zfish   396 WFLVTDWNPLTVWFYRECYLRFSTQPYS--THTL-DSSVHLCNNSIQK---HYQPSPDRSPSLPA 454

  Fly   790 ACHGHKWTIKSLWTYLANRGVRTDCLWEA-----LRSLVLRTILAGENGINSMIRANVESKYSCF 849
            .|   .|:.....::||..|  ...||:|     ::..|::|:|..::        :||.:.:.|
Zfish   455 EC---MWSCSQFRSWLAASG--RAALWKAVVVPGMQKAVIQTLLTAQD--------SVEPRKASF 506

  Fly   850 ELFGFDVILDSDLVPWLLEVNISPSLHSELPLDAHVKAPLVQGVLNTALYNVPPKLSLDKQKELA 914
            ||:|.|.:|..||.|||||:|.||::.....:.|.: .|.||   ...|     ::.||::.|..
Zfish   507 ELYGADFMLGRDLRPWLLEINASPTMAPSTGVTARL-CPAVQ---EDTL-----RVVLDRRSERN 562

  Fly   915 AEFSFPPGTQMCYDKRLYINYLSREEKIKHNTFTRKSMEDRNEYVDAILNNLTPDDVRCLIIAED 979
            .:..   |.|:.|                     :::..|..:||.  :|         |:|...
Zfish   563 TDTG---GFQLIY---------------------KQAAVDVPQYVG--VN---------LLIEGT 592

  Fly   980 ELARCAPLERIFPTDQTHKYL-KYNDTPRYYNRLLDAWESRYANNRTEGIALLRDYCQNKYHLQV 1043
            .:.|        |....||.| :.:..|.          |:..|:::   :||...|
Zfish   593 SIRR--------PRAPVHKSLIQSHPEPL----------SKSTNHKS---SLLSSPC-------- 628

  Fly  1044 PTPPAKKDSNDEETTPATPNTVKEEI 1069
               .:.|::..||...|.||....:|
Zfish   629 ---TSGKENQSEEVKRACPNLPNRKI 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4A	NP_723642.2	TTL	614..909	CDD:397308	97/336 (29%)
ttll3	NP_001038770.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	70..106		10/74 (14%)
		TTL	317..554	CDD:397308	88/264 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	605..640		10/58 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	682..713