Protein Alignment TTLL4A and Ttll4

DIOPT Version :9

• Sequence 1: NP_001162947.1
• Gene: TTLL4A / 47729
• FlyBaseID: FBgn0026147
• Length: 1071
• Species: Drosophila melanogaster
• Sequence 2: XP_001074653.1
• Gene: Ttll4 / 690512
• RGDID: 1594742
• Length: 1198
• Species: Rattus norvegicus
• Alignment Length: 1143
• Identity: 337/1143 - (29%)
• Similarity: 544/1143 - (47%)
• Gaps: 220/1143 - (19%)

  Fly    23 SRYCNADNTFCYYSYDN-CNL--IAPAWGN-----RQNQNQ-------------NSVPNQNHNLP 66
            |..|::..|.....:.| |.|  :...:.|     |.|..|             |....::.:||
  Rat    85 STLCSSGTTAVIAGHSNPCYLQSLPDLFSNTLLYRRTNVRQKPYQQLESFCLRSNPSEKRSFSLP 149

  Fly    67 TKRIP---TKQSARSS----YHQSAANSAPDSSLFTDAFGQ-------QSLVNQRIAGNKSCEYV 117
            .|.:|   |...|.||    ..|..|:|..|..|...|.|:       .|.::.:||...|.
  Rat   150 QKGLPVSVTANKATSSTVFPMAQPMASSPTDPYLSLAAAGENPSRKSLSSAISGKIASPLSS--- 211

  Fly   118 YQTVQRSEDQHSNRQYKQARSYAVDKEQQQQML-------LQPSIVYFDAELKKRKDRGGRVSND 175
            |:.:.      :|..:.:..|..|...|....|       :||...:..         ||  :.|
  Rat   212 YKPML------NNNSFMRPNSTKVPLSQATDGLKPVSSPKIQPVSWHHS---------GG--TGD 259

  Fly   176 YVDNSPDRYRPLN------------SPSPEPTWDNILSERPVQYQTTNQHYQ---HYFSYFYNRG 225
            .|....|...|.:            :|| .|:..||.:......|.:..:::   |......|..
  Rat   260 CVPQPGDHKVPQSIATVLDDVTAPMAPS-TPSTLNISTASVASSQCSQSNFRREAHPCGLDENTD 323

  Fly   226 AEKLSKPTFAAANSRKVPMSKFQK---AGASRRDSREVDGTVIIGRRDNSEDRTWQGQKYEKHVL 287
            ::..:|........||:....|:|   .|.....:..|:.:...|..:.|  |.|      |.::
  Rat   324 SQSATKEVHFTEAVRKLAAKGFEKMPRQGYQFEQACFVNPSFQWGLLNRS--RRW------KPLM 380

  Fly   288 KEKLPSNDLKADYLDNGWGGDPGSEDDYRDIKDSYDPVVVIDNGLEQVGVHRRYCRM-------T 345
            .::.|..|:..|.     |..||:.|..     ..|..|..   .:::.:|.....:       |
  Rat   381 GQRFPQEDIGLDS-----GILPGASDTL-----GLDSTVFC---TKRISIHLLASHVHGLNPSPT 432

  Fly   346 ENTVLDGSGDTLINNNNNELKIMRKSTDQPMPRLPMTPKRAKGGTVSTKKPMPTVHRVLLYSTQS 410
            ..:|:|   ..|:..:                |.|:.|.       |:.:|:.........|  |
  Rat   433 CGSVVD---PQLLGED----------------RAPVPPS-------SSLQPLGVAEVATRLS--S 469

  Fly   411 PRLGRKQQFSTQRLSVKQQSSKVLGAGDERQTVL---LLEPEHKQEDHRSAID----FDRNDDFD 468
            ..||:..:...:...:...|:|    ||...|.|   .||||..:::....::    .|.|::.:
  Rat   470 VHLGQPGKEPEEAKDLNSCSTK----GDCSPTDLRPKQLEPEDSEDELGDGLEDSCSHDENEEEE 530

  Fly   469 EDDDLDNLSNFDESDTASVLSDTEDGYRAHAFKLTHSVDRFSSPQSTPSFLSSQSSEDDLKNPDS 533
            .|.:..:||....|::.:::|             .:.||..|         .|.|:.:.:..|
  Rat   531 GDSECSSLSVVSPSESVAIIS-------------RNCVDLMS---------KSISNHEKVVRP-- 571

  Fly   534 LLVPSLFPYVPPYLSFSSNTKRGPRVPPDLHRVLKWRITNIMPKVVRLILANSGMRMLKKTNDWM 598
            .|:.||||.|.|.:.|.:..:|..::|.:..|:|:|:::.:.|.:|:..:..|..::.|:.:||:
  Rat   572 ALIYSLFPNVSPTIYFGTRDERVEKLPWEQRRLLRWKMSTVTPNIVKQTIGRSHFKISKRNDDWL 636

  Fly   599 GVWGKHLKSPCFKAIRSYQKINHLPGSFRIGRKDSCWKNLQRQMGKHSNKEFGFMPRTYIIPNDL 663
            |.||.|:|||.|::||.:||:||.||||:|||||..|:||.|...:...|||.|.|:::|:|.|.
  Rat   637 GCWGHHMKSPGFRSIREHQKLNHFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQDS 701

  Fly   664 GALRRHWPKYAQRNTKWIIKPPASARGAGIRVINRWGQIPKRRPLIVQKYIERPLLINGSKFDLR 728
            ..||:.|...:::  |||:||||||||.||:||::|.|:||||||:||:|:.:|.||:|||||||
  Rat   702 KLLRKAWESSSRQ--KWIVKPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLISGSKFDLR 764

  Fly   729 LYVLVTSVNPLRVFMYHNGLARFASVKYSAKTDTLNDRCMHLTNYSINKFSSNYSKNEDVNACHG 793
            :||.|||.:|||::::.:||.||||.|||....:|:::.|||||||:||.::.|..|.|..||.|
  Rat   765 IYVYVTSYDPLRIYLFSDGLVRFASCKYSPSMKSLSNKFMHLTNYSVNKKNAEYQANADETACQG 829

  Fly   794 HKWTIKSLWTYLANRGVRTDCLWEALRSLVLRTILAGENGINSMIRANVESKYSCFELFGFDVIL 858
            |||.:|:||.||:.:||.:|.:||.::.:|::||::.|..:.::::..|...|||.||||||::|
  Rat   830 HKWALKALWNYLSQKGVNSDAIWEKIKDVVVKTIISSEPYVTNLLKLYVRRPYSCHELFGFDIML 894

  Fly   859 DSDLVPWLLEVNISPSLHSELPLDAHVKAPLVQGVLNTALYNVPPKLSLDKQKELAAEFSFPPGT 923
            |.:|.||:|||||||||||..|||..:|..:::.:||.|.:.:|      ..:::.:..|.|..:
  Rat   895 DENLKPWVLEVNISPSLHSNSPLDISIKGQMIRDLLNLAGFVLP------NMEDILSSSSSPSSS 953

  Fly   924 ------------QMCYDKRLYINYLSRE----EKIKHNTFTRKSMEDRNEYVDAILNNLTPDDVR 972
                        :.|        .::.|    :|:|...:..:.:.|::.| .::|:.|||||||
  Rat   954 SGSSTSLPSSPREKC--------QMTPEHFTAQKMKKAYYLTQKVPDQDFY-SSVLDVLTPDDVR 1009

  Fly   973 CLIIAEDELARCAPLERIFPTDQTHKYLKYNDTPRYYNRLLDAWESRYANNRTEGIALLRDYCQN 1037
            .|:..|||.:|....|||||:..:.:||::.:.|||:|.|...||.:|..|:.:|:.|||::|..
  Rat  1010 VLVEMEDEFSRRGQFERIFPSRISSRYLRFFEQPRYFNILTTQWEQKYHGNKLKGVDLLRNWCYK 1074

  Fly  1038 KYHL----------QVPTPPAKKDSNDEETTPATPNTV 1065
            .:|.          .:||........|     .|||.|
  Rat  1075 GFHTGIVSDSAPLWSLPTSLMNASKGD-----GTPNAV 1107

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4A	NP_001162947.1	TTL	614..908	CDD:281171	149/293 (51%)
Ttll4	XP_001074653.1	TTL	652..944	CDD:397308	149/299 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340497
Domainoid	1	1.000	340	1.000	Domainoid score	I1059
eggNOG	1	0.900	-	-		E1_KOG2156
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250453at33208
OrthoFinder	1	1.000	-	-		FOG0006381
OrthoInspector	1	1.000	-	-		otm45378
orthoMCL	1	0.900	-	-		OOG6_101354
Panther	1	1.100	-	-	LDO	PTHR12241
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4643
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.710