Protein Alignment TTLL4A and ttll6

DIOPT Version :9

• Sequence 1: NP_001162947.1
• Gene: TTLL4A / 47729
• FlyBaseID: FBgn0026147
• Length: 1071
• Species: Drosophila melanogaster
• Sequence 2: NP_001098994.1
• Gene: ttll6 / 564075
• ZFINID: ZDB-GENE-080107-1
• Length: 778
• Species: Danio rerio
• Alignment Length: 562
• Identity: 161/562 - (28%)
• Similarity: 244/562 - (43%)
• Gaps: 125/562 - (22%)

  Fly   569 W-RITNIMPKVVRLILANSGMRMLKKTNDWMGVWGKHLKSPCFKAI------RSYQKINHLPGSF 626
            | .:||...:.||......|:|...:..||...|     :.|..::      :.||||||.||..
Zfish    55 WINLTNCKYESVRRAARRYGIREAAEGEDWTLYW-----TDCSVSLDRVMDMKRYQKINHFPGMN 114

  Fly   627 RIGRKDSCWKNLQRQMGKHSNKEFGFMPRTYIIPNDLGALRRHWPKYAQRNTKWIIKPPASARGA 691
            .|.|||...:|:.|.: |...||:...|||:.:|.|....:.:  ..|:::..:|.||.:..:|.
Zfish   115 EICRKDLLARNMNRML-KLFPKEYNIFPRTWCLPADYSDFQAY--TRAKKHKTFICKPDSGCQGR 176

  Fly   692 GIRVINRWGQIPKRRPLIVQKYIERPLLINGSKFDLRLYVLVTSVNPLRVFMYHNGLARFASVKY 756
            ||.:......|.....:|.|.|:.:|.:|:|.|||||:||||||.:|.|||||..||.||.:..|
Zfish   177 GIYLTKSSKDIRPGEHMICQVYMSKPFIIDGFKFDLRIYVLVTSCDPFRVFMYDEGLVRFCTTHY 241

  Fly   757 SAKT-DTLNDRCMHLTNYSINKFSSNYSKNEDVNACHGHKWTIKSLWTYLANRGVRTDCLWEALR 820
            :..| ..|.|.|||||||:|||.|.|:.::||.    |.|..:.|...::.:....|:.||..:.
Zfish   242 TEPTVSNLEDVCMHLTNYAINKHSENFVRDEDT----GSKRKLSSFKKHMEDMSYDTEKLWTDIE 302

  Fly   821 SLVLRTILAGENGINSMIRANVESKY-------SCFELFGFDVILDSDLVPWLLEVNISPSLHSE 878
            ..:::|:::.    :.:::.|.::.:       :|||:.||||:||..|.|||||||.|||..::
Zfish   303 DAIIKTLISA----HPILKHNYQTCFPNHASGSACFEILGFDVLLDRRLKPWLLEVNHSPSFTTD 363

  Fly   879 LPLDAHVKAPLVQGVLNTALYNVPPKLSLDKQKELAAEFSFPPGTQMCYDKRLYINYLSREEK-- 941
            ..||..||..|:...|  .|.|:.   :.|::|                        ::.|||
Zfish   364 SRLDREVKDSLLYDTL--VLINLG---ACDRRK------------------------ITEEEKRR 399

  Fly   942 IKHNTFTRKSMEDRNEYVDAILNNLTPDDVRCLIIAEDELARCAPLE--------------RIFP 992
            :|......:|.|.|||                    |...::.|.:|              ||||
Zfish   400 VKERLQQNRSREARNE--------------------EPRQSQAASMELMQKYEAKHMGGFRRIFP 444

  Fly   993 TDQTHKYLKY--NDTPRYYNRLLDAWESRYANNRTEGIALLRDYCQ------NKYHLQ------- 1042
            .|...||.||  :.:..:............|..:.:.:.|.::..:      .|..||
Zfish   445 RDGGEKYEKYFQHSSSLFQETAASKAREECARQQLQELRLKQEQKERDKKGSRKQDLQGESAGEK 509

  Fly  1043 ---VPTPPAKKDSND-----------EETTPATPNTVKEEIE 1070
               ..:.|..|.||.           |||..:.....|||.|
Zfish   510 VKPRKSQPPHKTSNSLPAMLELSSVREETPVSLERIEKEEAE 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4A	NP_001162947.1	TTL	614..908	CDD:281171	111/301 (37%)
ttll6	NP_001098994.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43
		TTL	99..379	CDD:281171	108/290 (37%)
		c-MTBD region. /evidence=ECO:0000250|UniProtKB:Q8N841	365..445		25/128 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	402..422		6/39 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	485..542		10/56 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	758..778

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250453at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920