Protein Alignment TTLL4A and ttll4

DIOPT Version :9

• Sequence 1: NP_001162947.1
• Gene: TTLL4A / 47729
• FlyBaseID: FBgn0026147
• Length: 1071
• Species: Drosophila melanogaster
• Sequence 2: XP_003199236.1
• Gene: ttll4 / 558702
• ZFINID: ZDB-GENE-070912-313
• Length: 1070
• Species: Danio rerio
• Alignment Length: 1072
• Identity: 348/1072 - (32%)
• Similarity: 544/1072 - (50%)
• Gaps: 210/1072 - (19%)

  Fly    51 QNQNQNSVPNQN-----------HNLPTKR----IPTKQSARSSYHQSAANSAPDSSLFTDAFGQ 100
            |..:.:|||:.|           ...||:|    :||.:..|:....:|:.:...:.|     ..
Zfish    44 QGSSSDSVPHPNVRVLYDQPYCISGTPTQRAYPHVPTVRVNRAQSTSAASLNGASNGL-----RA 103

  Fly   101 QSLVNQRIAGNKSCEYVYQTVQRSEDQ-HSNRQYKQARSYAVDKEQ-QQQMLLQPSIVYFDAELK 163
            ||::      :||..::..|......| |...:..:.:|..:.|.. ..|:.:.|:.   .:..|
Zfish   104 QSVL------SKSLPHINTTPAACHRQPHWKLESLRFKSGLLGKRAFSPQLSVCPAC---PSPPK 159

  Fly   164 KRKDRGGRVSNDYVDNSPDRYRPLNSPSPEPTWDNILSERPVQYQTTNQHYQHYFSYFYNRGAEK 228
            ....||          ..::..|.|..||   |            |:|:         ....:..
Zfish   160 SSSQRG----------VIEKVMPTNQSSP---W------------TSNK---------LRNNSNG 190

  Fly   229 LSKPTFAAANSRKVPMSKFQKAGASRRDSREVDGTVIIGRRDNSEDRTWQGQKYEKHVLKEKLPS 293
            :.:|..|     |:|....|:..:........:||...|.:.::              :|...||
Zfish   191 VVRPPNA-----KMPTFSKQEMHSPANVMSSCNGTFSRGLKVDA--------------MKPPQPS 236

  Fly   294 ---NDLKAD-YLDNGWGGDPGSEDDYRDIKD--SYDPVVVIDNGLE-----QVGVHRRYCRMTE- 346
               .|:..| .|::|           :.:||  .::.:.| ||..|     ..||:....|:|:
Zfish   237 VPLKDISTDVILNHG-----------KAVKDLRQFEKIKV-DNANELDCCMGHGVNEAPQRVTKI 289

  Fly   347 NTVLDGSGDTLINNN-------NNELKIMRKST---------DQPMPRLPMTPKRAKG-GTVSTK 394
            ::..:.:...::..|       .|.|..:::.|         |:.....||....|.. |.::.:
Zfish   290 SSEAEFNASAVLKPNVHARQRTINGLSNIKRITVGAVPVCLNDEESRFAPMETNSALSFGIIADE 354

  Fly   395 K--------------PMPTVHRVLLYSTQSPRLGR-KQQFSTQRLSVKQQSSKV--LG-----AG 437
            |              |..|.|.  :.|..||.:.. ..|.|..:|: |::|.:.  :|     ||
Zfish   355 KCPSDVVCIGGDCAIPEVTGHN--MPSPLSPSVYTVTNQISAIQLT-KEESCQASPVGPLNGEAG 416

  Fly   438 D-----ERQTVLLLEPEHKQEDHRSAIDFDRNDDFDEDDDLDNLSNFDESDTASVLSDTEDGYRA 497
            |     :||.:||...|.:..|       ...|||.:|||.|:.   |.|.|||:.:.:
Zfish   417 DDNSEIQRQGMLLDVDEEELPD-------KLEDDFSDDDDFDDC---DVSSTASMAASS------ 465

  Fly   498 HAFKLTHSVDRFSSPQSTPSFLSSQSSEDDLKNPDSLLVPSLFPYVPPYLSFSSNTKRGPRVPPD 562
                   :|:...||          ..|.||.. .|.|||||||::|..|.||:..:|...:|.:
Zfish   466 -------NVEEPISP----------DVEGDLVE-RSALVPSLFPHMPSTLYFSTANERVELLPAE 512

  Fly   563 LHRVLKWRITNIMPKVVRLILANSGMRMLKKTNDWMGVWGKHLKSPCFKAIRSYQKINHLPGSFR 627
            ..::|||:||.:.|.||:..:..|..:..||::||:|.||.|:|||.|||||.:||:||.||||:
Zfish   513 QMKLLKWKITTVTPNVVKNTIFRSHFKATKKSHDWLGCWGHHMKSPGFKAIREFQKLNHFPGSFQ 577

  Fly   628 IGRKDSCWKNLQRQMGKHSNKEFGFMPRTYIIPNDLGALRRHWPKYAQRNTKWIIKPPASARGAG 692
            |||||..|:||.:...:...:||||.||::|:|.|:..||:.|.....:. |||:||||||||.|
Zfish   578 IGRKDRLWRNLSKMQARFGKREFGFFPRSFILPQDIKLLRKAWDDGGSKQ-KWIVKPPASARGIG 641

  Fly   693 IRVINRWGQIPKRRPLIVQKYIERPLLINGSKFDLRLYVLVTSVNPLRVFMYHNGLARFASVKYS 757
            |:||::|.|:|::|||:||||:.:|.||:|:|||||:||.|||.:|||::::::||.||||.|||
Zfish   642 IQVIHKWSQMPRKRPLLVQKYLHKPYLISGNKFDLRIYVYVTSYDPLRIYIFNDGLVRFASCKYS 706

  Fly   758 AKTDTLNDRCMHLTNYSINKFSSNYSKNEDVNACHGHKWTIKSLWTYLANRGVRTDCLWEALRSL 822
            :...|||::.|||||||:||.:|.|..|.|..||.||||.:|:||.||.::|:.|..:||.::.:
Zfish   707 SSMKTLNNKFMHLTNYSVNKKNSEYQSNSDDKACQGHKWALKALWQYLGSQGINTTLIWEKIKDM 771

  Fly   823 VLRTILAGENGINSMIRANVESKYSCFELFGFDVILDSDLVPWLLEVNISPSLHSELPLDAHVKA 887
            |::||:|.:..:||:::.:|.|.|||.||||||::||.:|.||:|||||||||||..|||..:|.
Zfish   772 VIKTIIASDPYVNSLVKMHVRSPYSCHELFGFDIMLDENLKPWVLEVNISPSLHSNTPLDVSIKG 836

  Fly   888 PLVQGVLNTALYNVPPKLSLDKQKELAAEFSFPPG-------TQMCYDKR-LYINYLSREEKIKH 944
            .:::.:||.|.:.:|          |..:|: |.|       :.:|...| .:...:|.:||:|.
Zfish   837 QMIRDLLNLAGFVLP----------LRDDFA-PSGSSASSSTSSLCGGVREKWRPDISPDEKVKR 890

  Fly   945 NTFTRKSMEDRNEYVDAILNNLTPDDVRCLIIAEDELARCAPLERIFPTDQTHKYLKYNDTPRYY 1009
            ..:..:...|: ::...:|:.|||||||.|..:||||:|....||:||:..:.:||::.:.|||.
Zfish   891 AFYLSQRFGDQ-DFCATVLDVLTPDDVRVLAESEDELSRKGDFERVFPSHASSRYLRFFEQPRYL 954

  Fly  1010 NRLLDAWESRYANNRTEGIALLRDYCQNKYHL 1041
            |.||:.||.:|..:|::||.||||.|:.:.||
Zfish   955 NILLNQWEQKYWLSRSKGINLLRDLCEKRVHL 986

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4A	NP_001162947.1	TTL	614..908	CDD:281171	152/293 (52%)
ttll4	XP_003199236.1	TTL	564..844	CDD:281171	148/280 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580288
Domainoid	1	1.000	351	1.000	Domainoid score	I975
eggNOG	1	0.900	-	-		E1_KOG2156
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	515	1.000	Inparanoid score	I1257
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250453at33208
OrthoFinder	1	1.000	-	-		FOG0006381
OrthoInspector	1	1.000	-	-		otm26240
orthoMCL	1	0.900	-	-		OOG6_101354
Panther	1	1.100	-	-	LDO	PTHR12241
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4643
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.760