Protein Alignment TTLL4A and ttll4

DIOPT Version :10

• Sequence 1: NP_723642.2
• Gene: TTLL4A / 47729
• FlyBaseID: FBgn0026147
• Length: 1071
• Species: Drosophila melanogaster
• Sequence 2: NP_001417762.2
• Gene: ttll4 / 558702
• ZFINID: ZDB-GENE-070912-313
• Length: 1069
• Species: Danio rerio
• Alignment Length: 1072
• Identity: 349/1072 - (32%)
• Similarity: 545/1072 - (50%)
• Gaps: 211/1072 - (19%)

  Fly    51 QNQNQNSVPNQN-----------HNLPTKR----IPTKQSARSSYHQSAANSAPDSSLFTDAFGQ 100
            |..:.:|||:.|           ...||:|    :||.:..|:....:|:.:...:.|.|
Zfish    44 QGSSSDSVPHPNVRVLYDQPYCISGTPTQRAYPHVPTVRVNRAQSTSTASLNGASNGLRT----- 103

  Fly   101 QSLVNQRIAGNKSCEYVYQTVQRSEDQ-HSNRQYKQARSYAVDKEQ-QQQMLLQPSIVYFDAELK 163
            ||::      :||..::..|......| |...:..:.:|..:.|.. ..|:.:.|:.   .:..|
Zfish   104 QSVL------SKSLPHINTTPAACHRQPHWKLESLRFKSGLLGKRAFSPQLSVCPAC---PSPPK 159

  Fly   164 KRKDRGGRVSNDYVDNSPDRYRPLNSPSPEPTWDNILSERPVQYQTTNQHYQHYFSYFYNRGAEK 228
            ....||          ..::..|.|..||   |            |:|:         ....:..
Zfish   160 SSSQRG----------VIEKVMPTNQSSP---W------------TSNK---------LRNNSNG 190

  Fly   229 LSKPTFAAANSRKVPMSKFQKAGASRRDSREVDGTVIIGRRDNSEDRTWQGQKYEKHVLKEKLPS 293
            :.:|..|     |:|....|:..:........:||...|.:.::              :|...||
Zfish   191 VVRPPNA-----KMPTFSKQEMHSPANVMSSCNGTFSRGLKVDA--------------MKPPQPS 236

  Fly   294 ---NDLKAD-YLDNGWGGDPGSEDDYRDIKD--SYDPVVVIDNGLE-----QVGVHRRYCRMTE- 346
               .|:..| .|::|           :.:||  .::.:.| ||..|     ..||:....|:|:
Zfish   237 VPLKDISTDVILNHG-----------KAVKDLRQFEKIKV-DNANELDCCMGHGVNEAPQRVTKI 289

  Fly   347 NTVLDGSGDTLINNN-------NNELKIMRKST---------DQPMPRLPMTPKRAKG-GTVSTK 394
            ::..:.:...::..|       .|.|..:::.|         |:.....||....|.. |.::.:
Zfish   290 SSEAEFNASAVLKPNVHARQRTLNGLSNVKRITVGAVPVCLNDEESRFAPMETNSALSFGIIADE 354

  Fly   395 K--------------PMPTVHRVLLYSTQSPRLGR-KQQFSTQRLSVKQQSSKV--LG-----AG 437
            |              |..|.|.:   |.|||.:.. ..|.|..:|: |::|.:.  :|     ||
Zfish   355 KCPSDVVCIGGDCAIPEVTGHDI---SPQSPSVYTVTNQISAIQLT-KEESCQASPVGPLNGEAG 415

  Fly   438 D-----ERQTVLLLEPEHKQEDHRSAIDFDRNDDFDEDDDLDNLSNFDESDTASVLSDTEDGYRA 497
            |     :||.:||...|.:..|       ...|||.:|||.|:.   |.|.|||:.:.:
Zfish   416 DDNSEIQRQGMLLDVDEEELPD-------KLEDDFSDDDDFDDC---DVSSTASMAASS------ 464

  Fly   498 HAFKLTHSVDRFSSPQSTPSFLSSQSSEDDLKNPDSLLVPSLFPYVPPYLSFSSNTKRGPRVPPD 562
                   :|:...||          ..|.||.. .|.|||||||::|..|.||:..:|...:|.:
Zfish   465 -------NVEEPISP----------DVEGDLVE-RSALVPSLFPHMPSTLYFSTANERVELLPAE 511

  Fly   563 LHRVLKWRITNIMPKVVRLILANSGMRMLKKTNDWMGVWGKHLKSPCFKAIRSYQKINHLPGSFR 627
            ..::|||:||.:.|.||:..:..|..:..||::||:|.||.|:|||.|||||.:||:||.||||:
Zfish   512 QMKLLKWKITTVTPNVVKNTIFRSHFKATKKSHDWLGCWGHHMKSPGFKAIREFQKLNHFPGSFQ 576

  Fly   628 IGRKDSCWKNLQRQMGKHSNKEFGFMPRTYIIPNDLGALRRHWPKYAQRNTKWIIKPPASARGAG 692
            |||||..|:||.:...:...:||||.||::|:|.|:..||:.|.....:. |||:||||||||.|
Zfish   577 IGRKDRLWRNLSKMQARFGKREFGFFPRSFILPQDIKLLRKAWDDGGSKQ-KWIVKPPASARGIG 640

  Fly   693 IRVINRWGQIPKRRPLIVQKYIERPLLINGSKFDLRLYVLVTSVNPLRVFMYHNGLARFASVKYS 757
            |:||::|.|:|::|||:||||:.:|.||:|:|||||:||.|||.:||.::::::||.||||.|||
Zfish   641 IQVIHKWSQMPRKRPLLVQKYLHKPYLISGNKFDLRIYVYVTSYDPLCIYIFNDGLVRFASCKYS 705

  Fly   758 AKTDTLNDRCMHLTNYSINKFSSNYSKNEDVNACHGHKWTIKSLWTYLANRGVRTDCLWEALRSL 822
            :...|||::.|||||||:||.:|.|..|.|..||.||||.:|:||.||.::|:.|..:||.::.:
Zfish   706 SSMKTLNNKFMHLTNYSVNKKNSEYQSNSDDKACQGHKWALKALWQYLGSQGINTTLIWEKIKDM 770

  Fly   823 VLRTILAGENGINSMIRANVESKYSCFELFGFDVILDSDLVPWLLEVNISPSLHSELPLDAHVKA 887
            |::||:|.:..:||:::.:|.|.|||.||||||::||.:|.||:|||||||||||..|||..:|.
Zfish   771 VIKTIIASDPYVNSLVKMHVRSPYSCHELFGFDIMLDENLKPWVLEVNISPSLHSNTPLDVSIKG 835

  Fly   888 PLVQGVLNTALYNVPPKLSLDKQKELAAEFSFPPG-------TQMCYDKR-LYINYLSREEKIKH 944
            .:::.:||.|.:.:|          |..:|: |.|       :.:|...| .:...:|.:||:|.
Zfish   836 QMIRDLLNLAGFVLP----------LRDDFA-PSGSSASSSTSSLCGGVREKWRPDISPDEKVKR 889

  Fly   945 NTFTRKSMEDRNEYVDAILNNLTPDDVRCLIIAEDELARCAPLERIFPTDQTHKYLKYNDTPRYY 1009
            ..:..:...|: ::...:|:.|||||||.|..:||||:|....||:||:..:.:||::.:.|||.
Zfish   890 AFYLSQRFGDQ-DFCATVLDVLTPDDVRVLAESEDELSRKGDFERVFPSHASSRYLRFFEQPRYL 953

  Fly  1010 NRLLDAWESRYANNRTEGIALLRDYCQNKYHL 1041
            |.||:.||.:|..:|::||.||||.|:.:.||
Zfish   954 NILLNQWEQKYWLSRSKGINLLRDLCEKRVHL 985

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4A	NP_723642.2	TTL	614..909	CDD:397308	151/294 (51%)
ttll4	NP_001417762.2	None