Protein Alignment TTLL4A and Ttll3

DIOPT Version :10

• Sequence 1: NP_723642.2
• Gene: TTLL4A / 47729
• FlyBaseID: FBgn0026147
• Length: 1071
• Species: Drosophila melanogaster
• Sequence 2: XP_038963762.1
• Gene: Ttll3 / 362415
• RGDID: 1311255
• Length: 1031
• Species: Rattus norvegicus
• Alignment Length: 959
• Identity: 189/959 - (19%)
• Similarity: 313/959 - (32%)
• Gaps: 384/959 - (40%)

  Fly   107 RIAGNKSCEYVYQTVQRSEDQHSNRQYKQARSYAVDKEQQQQMLLQ---PSIVYFDAELKKRKDR 168
            |..|:..|.:    :|||:.......:.....:|.:.|.:....||   |      |..:....|
  Rat    23 RQEGSSECSW----LQRSQPPKHRTNFSSRCPWARNSEFRPSERLQWLGP------ASARPEVAR 77

  Fly   169 GGRVSND-------YVDNSPDRYRP--LNSPSPE-------PTWDNILSERPVQYQTTNQHYQHY 217
            .|....|       ::.::.:|:.|  |::.:||       ||.|..|.:.|
  Rat    78 SGNSQGDCSPLPARHLSSARERFVPGALDTVNPEPACSLVPPTLDEPLPDAP------------- 129

  Fly   218 FSYFYNRGAEKLSKPTFAAANSRKVPMSKFQKAGASRRDSREVDGTVIIGRRDNSEDR--TWQG- 279
                         .|....|.:...|::.::    .:.::.:|:|   :|..:.:.|.  .|:|
  Rat   130 -------------PPPGGEAQNGPPPLTPYR----LQTEAAKVEG---MGTLECTRDSLLLWRGF 174

  Fly   280 ---------------QKYEKHVLKEKL----------------------------------PSND 295
                           ...|:.|.::|:                                  ||.|
  Rat   175 TKGTPHHMGRLRNAKIHVERAVKQKKIFMIHGRYPVIRCLLRQRGWVEKKMVHPPGTILPPPSKD 239

  Fly   296 LKADYLDNGWGGDPGSEDDYRDIKDSY--DPVVVIDNGLE---QVGVHRRYCRMTEN-------- 347
            |.:..|    |....:||:..:..:.:  ..::.:|..||   ..|:|....||..|
  Rat   240 LDSSML----GDSDATEDEDEEESEMFRESQLLDLDGFLEFDDLDGIHALMSRMVRNETPYLIWT 300

  Fly   348 ---TVLDG---SGDTLINNNNNELKIMRKSTDQPMPRLPMTPKRAKGGTVSTKKPMPTVHRVLLY 406
               .|||.   |.|.:||:                        .|:.|:.:||..:....|.|.:
  Rat   301 TRRDVLDCRFLSKDQMINH------------------------YARAGSFTTKVGLCLNLRNLPW 341

  Fly   407 STQS------PRLGRKQQFSTQRLSVKQQSSKVLGAGDERQTVL----------LLEPEHKQEDH 455
            ..::      ||..|                  |||.|:::..:          :|:...|.|..
  Rat   342 FDEADADSFFPRCYR------------------LGAEDDKKAFIEDFWLTAARNVLKLVVKLEGR 388

  Fly   456 RSAIDFDRNDDFDEDDDL-DNLSNFDESDTASVLSDTEDGYRAHAFKLTHSVDRFSSPQSTPSFL 519
            ..:|.....    |::.| |......|....:|.||..|                .:..:....|
  Rat   389 SQSIPIQAR----EEEALEDTQPKKQEKKPVTVSSDFVD----------------EALSACEEHL 433

  Fly   520 SSQSSEDDLKNPDSLLVPSLFPYVPPYLSFSSNTKRGPRVPPDLHRVLKWRITNIMPKVVRLILA 584
            |:.:.:|..|:|::          |.|||           |.|
  Rat   434 SNIAHKDIDKDPNA----------PLYLS-----------PDD---------------------- 455

  Fly   585 NSGMRMLKKTNDWMGVWGKHLKSPCFKAIRSYQKINHLPGSFRIGRKDSCWKNLQRQMGKHSNKE 649
                            |...|:       |.||.:.                       .||
  Rat   456 ----------------WSLFLQ-------RYYQIVQ-----------------------PHS--- 471

  Fly   650 FGFMPRTYIIPNDLGALRRHWPKYAQR--------------------NTKWIIKPPASARGAGIR 694
                |:..:.|...||..|:.....||                    ...||:||.|.:||.||.
  Rat   472 ----PQVLLSPYSQGAELRYLEVQVQRCEDILQQLRAVVPQIDMEGDRNIWIVKPGAKSRGRGIT 532

  Fly   695 VINRWGQIPKR---RPL-------IVQKYIERPLLINGSKFDLRLYVLVTSVNPLRVFMYHNGLA 749
            .::...::.|.   .|:       ||||||||||||.|:|||||.:.|||..|||.|:.|.:...
  Rat   533 CMDHLDEMLKLVDCNPMLMKDGKWIVQKYIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYI 597

  Fly   750 RFASVKYSAKTDTLNDRCMHLTNYSINKFSSNYSKNEDVNACHGH-------KWTIKSLWTYLAN 807
            ||::..:|.|.   .|..:||.|.||.:...        .:||.|       .|:.:....:|
  Rat   598 RFSTQPFSLKN---LDNSVHLCNNSIQRHLE--------ASCHRHPMLPPDNMWSSQRFQAHL-- 649

  Fly   808 RGVRTDCLWE-----ALRSLVLRTILAGENGINSMIRANVESKYSCFELFGFDVILDSDLVPWLL 867
            :.|.....|.     .:::.|:..:...::        ||:.:.:.|||:|.|.:...|..|||:
  Rat   650 QEVDAPKAWSTVIVPGMKAAVIHALQTSQD--------NVQCRKASFELYGADFVFGEDFQPWLI 706

  Fly   868 EVNISPSLHSELPLDAHVKAPLVQGVLNTALYNVPPKLSLDKQKELAAE 916
            |:|.||::   .|..| |.|.|..||....|     ::.:|::.:.:.:
  Rat   707 EINASPTM---APSTA-VTARLCAGVQADTL-----RVVIDRRMDRSCD 746

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4A	NP_723642.2	TTL	614..909	CDD:397308	90/336 (27%)
Ttll3	XP_038963762.1	TTL	439..743	CDD:397308	102/429 (24%)