Protein Alignment TTLL4A and Ttll10

DIOPT Version :10

• Sequence 1: NP_723642.2
• Gene: TTLL4A / 47729
• FlyBaseID: FBgn0026147
• Length: 1071
• Species: Drosophila melanogaster
• Sequence 2: NP_001164004.1
• Gene: Ttll10 / 298692
• RGDID: 1560839
• Length: 727
• Species: Rattus norvegicus
• Alignment Length: 712
• Identity: 155/712 - (21%)
• Similarity: 255/712 - (35%)
• Gaps: 217/712 - (30%)

  Fly   378 RLPMTPKRAKGGTVSTKKP-----MPTVH---RVLLYSTQSPRLGRKQQFSTQRLSVKQQS-SKV 433
            |....|:|..|.|.:::.|     ||...   |.:.|..|.||  ....|...:.|...|| :||
  Rat    99 RAARRPRRGVGTTSASRAPRPGALMPATRNRPRFIHYRVQPPR--THVSFKRPKRSRTHQSHTKV 161

  Fly   434 LGAGDERQTVLLLE----PEHKQEDHRSAIDFDRNDDFDEDDDLDNLSNFDESDTASVLSDTEDG 494
            .|...|::....:|    ||..|                .:.|.|||.   |.:.|.:...:.:|
  Rat   162 PGWTHEKRMGSSVEEGLRPELSQ----------------LEQDADNLG---EEEAARLPVTSLNG 207

  Fly   495 YRAHAFKLTHSVDRFSSPQSTP----------SFLSS-------QSSED-----------DLKNP 531
                   |....||..:|...|          |.:|:       |.::|           ::|..
  Rat   208 -------LLMEGDRHPNPGQGPFFYIGGTNGASIISNYCESKGWQRTQDSRCEDYKLKWCEIKCR 265

  Fly   532 DSLLVPSLFPYVPPYLSFSSNTKRGPRVPPDLHRVLKWRITNIMPKVVRLILANSGMRMLKKTND 596
            |:            |.||....:            |.:::.|     .:|:....|
  Rat   266 DN------------YCSFREGQQ------------LLFQLPN-----NKLLTTKIG--------- 292

  Fly   597 WMGVWGKHLKSPCFKAIRSYQKINHLPGSFRIGRKDSCWKNLQRQMGKHSNKEFGFMPRTYIIPN 661
                    |.|...:..|:..|...:|.:             |.::.|...    |.|.||.:
  Rat   293 --------LLSALREHARTLSKARLMPST-------------QAKVLKMDE----FFPETYRL-- 330

  Fly   662 DLGALRRHWPKYAQRNTKWIIKPPASARGAGIRVINR-------------------WGQIPKRRP 707
            |:...|:.:.........||.||.||.:|.||.:|..                   :.::|.|.|
  Rat   331 DIRDERQAFFTLFDETQMWICKPTASNQGKGIFLIRSQEEAAALQAKTQSIEDDPIYRKMPFRAP 395

  Fly   708 --LIVQKYIERPLLINGSKFDLRLYVLVTSVNPLRVFMYHNGLARFASVKYSAKTDTLNDRCMHL 770
              .:||:|::.|||::|.|||:|.|:|:....|..||..| |.||.....|:..:..|:.   ||
  Rat   396 QARVVQRYVQNPLLLDGKKFDVRSYMLIACAMPYMVFFGH-GYARLTLSLYNPHSSDLSG---HL 456

  Fly   771 TNYSINKFSSNYSKNEDVNACHGHKWTIKSLWTYL-----ANRGVRTDCLW----EALRSLVLRT 826
            ||..:.|.|..|...:|...     |:::.|..|:     .::|:..|.::    :.::.::...
  Rat   457 TNQFMQKKSPLYMLLKDSTV-----WSMEHLNRYINDKFRKSKGLPRDWVFTTFTKRMQQIMSHC 516

  Fly   827 ILAGENGINSMIRANVESKYSCFELFGFDVILDSDLVPWLLEVNISPSLHSELPLDAHVKAPLVQ 891
            .||        :::.:|.|...|:|.|.|.::|.:...||||:|.:|:||:...:...|...:|.
  Rat   517 FLA--------VKSKLECKLGYFDLIGCDFLIDENFKVWLLEMNSNPALHTNCEVLKEVIPGVVM 573

  Fly   892 GVLNTALYNVPPKLSLDKQKELAAEFSF-------------------PPGTQMCYDKRLYINYLS 937
            ..|:.||......|...|...|.::..|                   || .::.|...   |:..
  Rat   574 ETLDLALETCQKSLHSQKMLPLQSQRRFVLLYNGETTDLWPRLGSSRPP-IRLPYANS---NHAR 634

  Fly   938 REEKIKHNTFT------------RKSMEDRNEYVDAILNNLTPDDVRCLIIAEDELARCAPL 987
            ...:|..::.|            ||||..|...:.|...:...|. ..:.|.|.|.:.|:.|
  Rat   635 STCEISSSSLTSTRVTIADRPAARKSMSSRTAPICASRKSRLSDS-GGVSIEESETSVCSGL 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4A	NP_723642.2	TTL	614..909	CDD:397308	82/324 (25%)
Ttll10	NP_001164004.1	PHA03247	<53..125	CDD:223021	7/25 (28%)
		CPSase_L_D2	323..576	CDD:473076	73/271 (27%)