DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TTLL4A and Ttll2

DIOPT Version :9

Sequence 1:	NP_001162947.1	Gene:	TTLL4A / 47729	FlyBaseID:	FBgn0026147	Length:	1071	Species:	Drosophila melanogaster
Sequence 2:	XP_006227981.1	Gene:	Ttll2 / 292311	RGDID:	1305200	Length:	541	Species:	Rattus norvegicus

Alignment Length:	388	Identity:	126/388 - (32%)
Similarity:	185/388 - (47%)	Gaps:	62/388 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   567 LKWRITNIMPKVVRLILANSGM----RMLKKTNDWMGVWGKHLKSPCFKA-----IRSYQKINHL 622
            |.:|:....|.||:.:|...|.    ...:...||...|    :|..|:.     |:.:|::||.
  Rat    45 LVFRVDESTPGVVQSVLLERGWDKFDEQCQDVEDWNLYW----RSSSFRMAEYVNIKPWQRLNHH 105

  Fly   623 PGSFRIGRKDSCWKNLQRQMGKHSNKEFGFMPRTYIIPNDLGA-LRRHWPKYAQRNTK---WIIK 683
            ||:..:.|||...|:|......:....:.|.|.|:|:|:|... :.:::.:.....||   ||.|
  Rat   106 PGTTSLTRKDCLAKHLAHMRRLYGESIYEFTPLTFIMPSDYTKFVAKYFKEKQDLGTKPSYWICK 170

  Fly   684 PPASARGAGIRVINRWGQIPKRRPLIVQKYIERPLLINGSKFDLRLYVLVTSVNPLRVFMYHNGL 748
            |...::|.||.:.:....:..:...:|||||..|||:...|.|||:||.||...||.::||..||
  Rat   171 PAKLSQGRGIIIFSDIRDLMFKDAYVVQKYICNPLLVGRYKCDLRIYVCVTGFKPLTIYMYQEGL 235

  Fly   749 ARFASVKYSAKTDTLNDRCMHLTNYSINKFSSNYSKNEDVNACHGHKWTIKSLWTYLANRGVRTD 813
            .|||:.|:.  ...|.|...||||.||||..::|.|.::| ...|.|||:...::||.|..|...
  Rat   236 VRFATEKFD--LSNLEDYYSHLTNSSINKLGASYEKIKEV-VGQGCKWTLSRFFSYLRNWDVDDL 297

  Fly   814 CLWEALRSLVLRTILAGENGINSMIRANVESKYSCFELFGFDVILDSDLVPWLLEVNISPSLHSE 878
            .|...:..:|:.|:||        :..:|....:||||||||:::|.:|.|||||||.||:|..|
  Rat   298 LLRRKINHMVILTVLA--------MAPSVPVANNCFELFGFDILIDDNLKPWLLEVNYSPALSLE 354

  Fly   879 LPLDAHVKAPLVQGVLNTALYNVPPKLSLDKQKELAAEFSFPPGTQMCYDKRLYINYLSREEK 941
            ...|..||..||..::                 ||                 ||:|.|..|||
  Rat   355 CSTDVSVKRSLVHDII-----------------EL-----------------LYLNGLRSEEK 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4A	NP_001162947.1	TTL	614..908	CDD:281171	104/297 (35%)
Ttll2	XP_006227981.1	TTL	98..371	CDD:281171	104/300 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250453at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920