Protein Alignment TTLL4A and ttll-5

DIOPT Version :10

• Sequence 1: NP_723642.2
• Gene: TTLL4A / 47729
• FlyBaseID: FBgn0026147
• Length: 1071
• Species: Drosophila melanogaster
• Sequence 2: NP_001256331.1
• Gene: ttll-5 / 179582
• WormBaseID: WBGene00008331
• Length: 730
• Species: Caenorhabditis elegans
• Alignment Length: 620
• Identity: 165/620 - (26%)
• Similarity: 282/620 - (45%)
• Gaps: 133/620 - (21%)

  Fly   437 GDERQTVLL-----LEPEHKQEDHRSAIDFDRNDDFDEDDDLDNLSNFDESDTASVLSDTEDGYR 496
            |..|:.:.|     |.|::..|::.:        |.:..|.:..:...||::.....|.::|
 Worm    21 GTRREGLFLCKRLKLRPDNYLEEYCA--------DLEVIDIMAPIRPADETERCPPTSTSDD--- 74

  Fly   497 AHAFKLTHSVDRFSSPQSTPSFLSSQSSEDDLKNPDSLLVPSLFPYVPPYLSFSSN--------- 552
                            |....:|.|::.:.  :|.|             |:.|||:
 Worm    75 ----------------QEAGDYLVSRNKKS--RNSD-------------YMLFSSDALVHIAHDA 108

  Fly   553 ------TKRGPRVPPDLHRVLKWRITNIMPKVVRLILANSGMRMLKKTND-----WMGVWGKHLK 606
                  |..|.|:.      |.:::.....:::|.:..:.|.......|.     |||.   .:|
 Worm   109 KVSEKYTWLGERLR------LTFKMMRSDSRLIRTMCHSHGFMQCSSKNPSVNVIWMGA---PVK 164

  Fly   607 SPCFKAIRSYQKINHLPGSFRIGRKDSCWKNLQRQMGKHSNKEFGFMPRTYIIPNDLGALRRHWP 671
            |...:.:..:|::|..|.|..:.:||..::|::|..... .:.|.|:|..|:.|.:...:...:.
 Worm   165 SVRMRELMPWQRLNQFPRSTELTKKDRLYENIERSKSIF-GESFDFIPEFYVTPRENRKMENAFV 228

  Fly   672 KYAQRNT----------KWIIKPPASARGAGIRVINRWGQIPKRRPLIVQKYIERPLLINGSKFD 726
            :.|:...          ::|:||..|.:|.||...|....||...||:|.:|::.|.|:|..|||
 Worm   229 RVAKEIAAAGGELCFPGEFIVKPTNSRQGKGIFFANSMADIPAEGPLLVSRYLKDPYLVNNHKFD 293

  Fly   727 LRLYVLVTSVNPLRVFMYHNGLARFASVKYSAKTDTL-NDRCMHLTNYSINKFSSNYSKNEDVNA 790
            ||:||.|||..||..::|..||||.||..|.....:. ::..:|||||||||.|:::.:||.:::
 Worm   294 LRIYVAVTSFYPLVAYVYSEGLARLASRPYDTSASSADSNEYVHLTNYSINKNSTSFVRNESMSS 358

  Fly   791 CH-GHKWTIKSLWTYLANRGVRTDCLWEALRSLVLRTILAGENGINSMIRANVESKYSC--FELF 852
            .. |||||:.:|..|:.|.|.....|...:..|:::::|:.:|.:.:..|.|:  :::|  ||||
 Worm   359 EDLGHKWTLGALLRYVENEGKDAKLLMLRIEDLIVKSLLSIQNSVATASRTNL--RFACTNFELF 421

  Fly   853 GFDVILDSDLVPWLLEVNISPSLHSELPLDAHVKAPLVQGVLNTA---------LYNVPPKL--S 906
            ||||::|..|.|||||||:||||..:.|||:.:|..|:..:||.|         :.:|.|.|  |
 Worm   422 GFDVLVDQALKPWLLEVNLSPSLACDAPLDSLLKTRLIADLLNLACVPLLDRKIIDSVTPALRKS 486

  Fly   907 LDKQKELAAEFSFPPGTQMCYD--KRLYINYLSREEKIKHNTFTRKSMEDRNEYVDAILNNLTPD 969
            ::.|:..::|........||..  ||       |...:|.:...:|.:...        .:|.|:
 Worm   487 MNSQESESSETDDLELDPMCAKTLKR-------RPVGLKRSVLNKKIVSGS--------TSLIPN 536

  Fly   970 DVRCLIIAEDELARCAPLE--------RIFPTDQT 996
            :.:..    |::.|.|.||        |:||.:.|
 Worm   537 NEKKF----DQIVRKAELEDGRRGDFIRVFPRNGT 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4A	NP_723642.2	TTL	614..909	CDD:397308	112/319 (35%)
ttll-5	NP_001256331.1	TTL	173..476	CDD:397308	108/305 (35%)