Protein Alignment TTLL4A and TTLL9

DIOPT Version :10

• Sequence 1: NP_723642.2
• Gene: TTLL4A / 47729
• FlyBaseID: FBgn0026147
• Length: 1071
• Species: Drosophila melanogaster
• Sequence 2: NP_001008409.1
• Gene: TTLL9 / 164395
• HGNCID: 16118
• Length: 439
• Species: Homo sapiens
• Alignment Length: 372
• Identity: 99/372 - (26%)
• Similarity: 159/372 - (42%)
• Gaps: 101/372 - (27%)

  Fly   572 TNIMPKVVRLILANSGMRMLKKTNDWMGVWGKHLKSPC----------FKAIRSYQKINHLPGSF 626
            |.:|..::.::....|...:|...:|...|       |          ...:..:.:|:|....:
Human    48 TTLMNTLMDVLRHRPGWVEVKDEGEWDFYW-------CDVSWLRENFDHTYMDEHVRISHFRNHY 105

  Fly   627 RIGRKDSCWKN-------LQRQMGKHSNKEFGFMPRTYIIPNDLGALRRHWPKYAQRNTKWIIKP 684
            .:.||:...||       |:|:.||....:..|.|:|:.:|.:.......:.|  .....||:||
Human   106 ELTRKNYMVKNLKRFRKQLEREAGKLEAAKCDFFPKTFEMPCEYHLFVEEFRK--NPGITWIMKP 168

  Fly   685 PASARGAGIRVINR------W-----------GQIPKRRPLIVQKYIERPLLINGSKFDLRLYVL 732
            .|.::|.||.:..|      |           ..||... .:.|:|||.|.||.|.|||||:|||
Human   169 VARSQGKGIFLFRRLKDIVDWRKDTRSSDDQKDDIPVEN-YVAQRYIENPYLIGGRKFDLRVYVL 232

  Fly   733 VTSVNPLRVFMYHNGLARFASVKYSAKTDTLNDRCM----------HLTNYSINKFSSNYSKNED 787
            |.||              ||             .|:          ||||.::.|.|.:|...:
Human   233 VMSV--------------FA-------------ECLLWSGHRRQDVHLTNVAVQKTSPDYHPKK- 269

  Fly   788 VNACHGHKWTIKSLWTYLANR----GVRTDCLWEALRSLVLRTILAGENGINSMIRANVESKYSC 848
                 |.|||::....|||::    .|.|  |:..:.::.:::       :.|:.:..:..|: |
Human   270 -----GCKWTLQRFRQYLASKHGPEAVET--LFRDIDNIFVKS-------LQSVQKVIISDKH-C 319

  Fly   849 FELFGFDVILDSDLVPWLLEVNISPSLHSELPLDAHVKAPLVQGVLN 895
            |||:|:|:::|.||.|||||||.||||.:....|..:|..|::..|:
Human   320 FELYGYDILIDQDLKPWLLEVNASPSLTASSQEDYELKTCLLEDTLH 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4A	NP_723642.2	TTL	614..909	CDD:397308	92/320 (29%)
TTLL9	NP_001008409.1	TTL	92..368	CDD:397308	92/321 (29%)