Protein Alignment TTLL4A and LOC100490189

DIOPT Version :10

• Sequence 1: NP_723642.2
• Gene: TTLL4A / 47729
• FlyBaseID: FBgn0026147
• Length: 1071
• Species: Drosophila melanogaster
• Sequence 2: XP_002933977.1
• Gene: LOC100490189 / 100490189
• XenbaseID: XB-GENE-29080059
• Length: 746
• Species: Xenopus tropicalis
• Alignment Length: 750
• Identity: 166/750 - (22%)
• Similarity: 267/750 - (35%)
• Gaps: 235/750 - (31%)

  Fly   373 DQPMPRLPMTPKRAKGGTVSTK-KPMPTV---HRVLLYSTQSPRLGRKQQFSTQRLSVKQQSSKV 433
            ::.:||..:.|::.|.....|| ...||.   |.|      ||..|...: :|.|..:...|.|
 Frog     2 ERTIPRKTVRPQQKKECNSDTKPNKQPTAKDKHDV------SPTKGHVSK-NTHRKKINPDSLK- 58

  Fly   434 LGAGDERQTVLLLEPEHKQEDHRSAIDFDRNDDFDEDDDLDNLSNFDESDTASVLSDTEDGY--- 495
                   |..||:|         .||  ..|..|                       |..||
 Frog    59 -------QAKLLVE---------KAI--QENKIF-----------------------TIQGYYPY 82

  Fly   496 -------RAHAFKLTHSV--DRFSSPQSTPSFLSSQSSEDDLKNPDSLLVPSLFPYVPPYLSFSS 551
                   |....|..|..  |.|..|:......|..     |:|.|    |: |.:||.|....|
 Frog    83 IRSGLRIRGWVEKNFHKSQHDYFDDPEGICDLTSRL-----LRNQD----PN-FVWVPTYNCLDS 137

  Fly   552 NTKRGPRVPPDLH---------------RVLKW----RITNIMPKVVRL---------------- 581
            ...:..::..:.:               |.|.|    .:.:..|:..||
 Frog   138 RLLKNDQIIMNHYSKSVFTTKVGLCLNLRNLHWFADADLNSFFPRCYRLGVKEEKQAFIEDFRLT 202

  Fly   582 -------ILANSGMRM-----LKK------------------TNDWMGVWGKHLKSPCFKAIRSY 616
                   :::..|..|     :||                  |:...|| ..|:.....||.:.|
 Frog   203 AACSILKLVSREGKNMPNRRDVKKESTPALLLKYNKKAQPLITSVNTGV-PVHIIKTALKACKQY 266

  Fly   617 -QKINHLPGSFRIGRKDSC----WKNL----QRQMGKHS--NKEFGFMPRTYIIPNDLGALRRHW 670
             ..:.|....:::|..::.    ||..    .:.:.|:.  |:...::.:...|...|.|::...
 Frog   267 LNTLEHEDIDWKLGSTNAITEDEWKEFLDGYYQVIHKNRIINEAENYVSQCQDILQKLKAVKPQL 331

  Fly   671 PKYAQRNTKWIIKPPASARGAGIRVINRWGQIPK----------RRPLIVQKYIERPLLINGSKF 725
            ....:||. ||:||.||:||.||..|:...:..|          ...|:|||||||||||.|:||
 Frog   332 DIDGERNI-WIVKPGASSRGRGITCIDYLEEALKFVDCDPPFINHDKLVVQKYIERPLLIYGTKF 395

  Fly   726 DLRLYVLVTSVNPLRVFMYHNGLARFASVKYSAKTDTLNDRCMHLTNYSINKFSSNY--SKNEDV 788
            |:|.:.:||:.|||.::.|.....||:|..:|.|  .|:. .:||.|.:|.|   ||  |::...
 Frog   396 DVRQWFVVTNWNPLTIWYYKECYLRFSSQPFSLK--NLHS-SIHLCNNAIQK---NYSISQSRHP 454

  Fly   789 NACHGHKWTIKSLWTYLANRGVRTDCLWE-----ALRSLVLRTILAGENGINSMIRANVESKYSC 848
            .....:.|.......||...|...  .|:     .:::.::.|:...::        ..|.:.:.
 Frog   455 QLPKENMWFKNQFQDYLQMTGATN--AWKEIIEPGMKAAIIHTMQCSQD--------MEEGRKNS 509

  Fly   849 FELFGFDVILDSDLVPWLLEVNISPSLHSELPLDAHVKAPLVQGVLNTALYNVPPKLSLDKQKEL 913
            |:::|.|.:...:..|||:|:|.:|    ::.|...|.:.||..|....|.     |.||:::..
 Frog   510 FQIYGADFMFGENFQPWLIEINANP----DMSLSTSVTSRLVARVQEDLLC-----LILDRKQHA 565

  Fly   914 AAE------------FSFPPGTQMCYDKRLYINYLSREEKIKHNTFTRKSMEDRNEYVDAILNNL 966
            .|:            ...|    :||.|:|.         :|.|...:...:::|:....
 Frog   566 DADVGVFELIYKQPVIKIP----LCYTKQLL---------VKGNEIKKLMTDEKNQMFKG----- 612

  Fly   967 TPDDVRCLIIAEDELARCAPLERIFPTDQTHKYLK 1001
                    .||:||...|. |.|. .|..|.|.:|
 Frog   613 --------SIAKDERGPCL-LHRT-KTTATWKEIK 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4A	NP_723642.2	TTL	614..909	CDD:397308	85/322 (26%)
LOC100490189	XP_002933977.1	TTL	290..555	CDD:397308	79/285 (28%)