Protein Alignment CG17829 and ZNF436

DIOPT Version :9

• Sequence 1: NP_652054.1
• Gene: CG17829 / 47718
• FlyBaseID: FBgn0025635
• Length: 467
• Species: Drosophila melanogaster
• Sequence 2: NP_001070663.1
• Gene: ZNF436 / 80818
• HGNCID: 20814
• Length: 470
• Species: Homo sapiens
• Alignment Length: 341
• Identity: 81/341 - (23%)
• Similarity: 131/341 - (38%)
• Gaps: 71/341 - (20%)

  Fly    65 EHTEHQCTWNSCDFRTENQVEFERHSYYHGYYLNLLLQGKLECDLHPEIPA------CTAPARLM 123
            :.:|.|  |.  |...|..|.:.             ||...:..:|.|:..      |:...:..
Human   100 DRSERQ--WG--DLTAEEWVSYP-------------LQPVTDLLVHKEVHTGIRYHICSHCGKAF 147

  Fly   124 EKLPALGQN---------FRCGWTDCEREFVSIVEFQDHIVKHALFEYDIQKTPEDERPKTMCNW 179
            .::..|.::         ::|  .:|.:.|    ....|:::|       |:|...|||.. ||
Human   148 SQISDLNRHQKTHTGDRPYKC--YECGKGF----SRSSHLIQH-------QRTHTGERPYD-CN- 197

  Fly   180 AMCHKHMGNKYRLIEHISTHSNKKQVACFHCGELFRTKTTLFDHLRRQPENNTNSFQCAQCFKFF 244
             .|.|..|....||:|.:.|:.:|...|..||:.|...:.|..|.|  ..:....::|.:|.|.|
Human   198 -ECGKSFGRSSHLIQHQTIHTGEKPHKCNECGKSFCRLSHLIQHQR--THSGEKPYECEECGKSF 259

  Fly   245 ATKKLLKSHVVRHV--NCYKCTMCDMTCSSASSLTTHIRYRHLKDKPLKCSECDTRCVRESDLAK 307
            :....|..|...|.  ..|:|..|....|..|.|..|.|. |..::|.||.||.....:.|||.:
Human   260 SRSSHLAQHQRTHTGEKPYECNECGRGFSERSDLIKHYRV-HTGERPYKCDECGKNFSQNSDLVR 323

  Fly   308 HVQIVHSKTVHQCEHP----DCHYSVRTYTQMRRHFLEVHGNNPILYACHCCERFFKSGKSLSAH 368
            |      :..|..|.|    :|..:....:.:.:|.....|..|  |.|:.|.:.|    |.|:|
Human   324 H------RRAHTGEKPYHCNECGENFSRISHLVQHQRTHTGEKP--YECNACGKSF----SRSSH 376

  Fly   369 LMKKHGFRLPSGHKRF 384
            |:...  ::.:|.|.:
Human   377 LITHQ--KIHTGEKPY 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	6/16 (38%)
		C2H2 Zn finger	207..225	CDD:275368	6/17 (35%)
		C2H2 Zn finger	237..257	CDD:275368	6/19 (32%)
		C2H2 Zn finger	263..284	CDD:275368	7/20 (35%)
		C2H2 Zn finger	292..311	CDD:275368	7/18 (39%)
		C2H2 Zn finger	352..373	CDD:275368	7/20 (35%)
ZNF436	NP_001070663.1	KRAB	13..54	CDD:307490
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	62..103		0/2 (0%)
		C2H2 Zn finger	140..160	CDD:275368	2/19 (11%)
		zf-H2C2_2	152..177	CDD:316026	4/30 (13%)
		C2H2 Zn finger	168..188	CDD:275368	6/32 (19%)
		zf-H2C2_2	180..205	CDD:316026	11/34 (32%)
		C2H2 Zn finger	196..216	CDD:275368	8/21 (38%)
		COG5048	<212..467	CDD:227381	52/196 (27%)
		C2H2 Zn finger	224..244	CDD:275368	7/21 (33%)
		C2H2 Zn finger	252..272	CDD:275368	6/19 (32%)
		C2H2 Zn finger	280..300	CDD:275368	7/20 (35%)
		C2H2 Zn finger	308..328	CDD:275368	7/25 (28%)
		C2H2 Zn finger	336..356	CDD:275368	2/19 (11%)
		C2H2 Zn finger	364..384	CDD:275368	7/25 (28%)
		C2H2 Zn finger	392..412	CDD:275368
		C2H2 Zn finger	420..440	CDD:275368
		C2H2 Zn finger	448..468	CDD:275368

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910