DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17829 and zgc:162972

DIOPT Version :9

Sequence 1:	NP_652054.1	Gene:	CG17829 / 47718	FlyBaseID:	FBgn0025635	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_021323880.1	Gene:	zgc:162972 / 558355	ZFINID:	ZDB-GENE-070424-49	Length:	817	Species:	Danio rerio

Alignment Length:	502	Identity:	125/502 - (24%)
Similarity:	173/502 - (34%)	Gaps:	130/502 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 QSSVPAPQPPGKRKKPAELELTCGWRDCQEICTGEWSLNGHIGDHL--EHYAKAQDDRG------ 61
            ||.....:....:.|..|...||  :.|.||.|...||..|...|.  :||..::..:.
Zfish   369 QSGTHITEQSSLKIKTGETAFTC--KQCGEIFTTNQSLESHKVIHTGEQHYFCSECGKSFTQMRY 431

  Fly    62 ------AHAEHTEHQCTWNSCDFRTENQVEFERHSYYH-GYYLNLLLQGKLECDLHPEIPACTAP 119
                  .||  .:|..|...||.....:...|.|...| |       :....|      |.|...
Zfish   432 LKNHMKIHA--GDHPFTCPECDKCFTMKHSLESHLKIHTG-------EKPFTC------PDCGKK 481

  Fly   120 ARLMEKL-----------PALGQNFRCGWTDCEREFVSIVEFQDHIVKHA--------------- 158
            .||.:.|           |...||  ||.:..|::.:     ..|:..|.
Zfish   482 FRLKQSLEGHMRIHTGEKPYTCQN--CGKSFREKQIL-----DTHLTIHTGEKPYSCPECGKSFR 539

  Fly   159 ---LFEYDIQKTPEDERPKTMCNWAMCHKHMGNKYRLIEHISTHSNKKQVACFHCGELFRTKTTL 220
               ..|..| ||...|:|.| |.  .|.|....|..|..|:..|:.:|..:|..||..||.|..|
Zfish   540 VKKCLENHI-KTHTGEKPYT-CQ--ECGKSFAIKQNLERHMRIHTGEKPYSCPECGRSFRVKQDL 600

  Fly   221 FDHLRRQPENNTNSFQCAQCFKFFATKKLLKSHVVRHV--------NC----------------- 260
            ..|:|  .......|.|.||.|.|...|.|:||:..|.        :|
Zfish   601 KIHVR--IHTGEKPFSCQQCGKSFTENKKLESHMRIHTGEKPFVCSHCGKNFRGKQNLESHMRLH 663

  Fly   261 -----YKCTMCDMTCSSASSLTTHIRYRHLKDKPLKCSECDTRCVRESDLAKHVQIVHSKTVHQC 320
                 |.|..|..:.:...||..||| .|..:||..|.:|......:|:|..|::|...:....|
Zfish   664 TGSKPYTCPQCGKSYNQQKSLDIHIR-THTGEKPFACDQCGKSFTHQSNLKGHIRIHTGEKPFTC 727

  Fly   321 EHPDCHYSVRTYTQMRRHFLEVH-GNNPILYACHCCERFFKSGKSLSAHLMKKHGFRLPSGHKRF 384
              |.|..|....|::.|| .::| |..|  |.|..|::.|...:||..| ||.|....|
Zfish   728 --PQCGKSFIEKTKLERH-KKIHSGEKP--YDCQHCKKSFTLKQSLDIH-MKLHTREKP------ 780

  Fly   385 TYRVDENGFYRLETTRLESLEVTQQILSPQVNDSLAKPGTGSCYEIV 431
             |...:.|         :|..|.|:::|.....:..||..|  .|:|
Zfish   781 -YSCQQCG---------KSFRVKQKLVSHMTVHTEEKPALG--VEVV 815

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	5/16 (31%)
		C2H2 Zn finger	207..225	CDD:275368	8/17 (47%)
		C2H2 Zn finger	237..257	CDD:275368	9/19 (47%)
		C2H2 Zn finger	263..284	CDD:275368	7/20 (35%)
		C2H2 Zn finger	292..311	CDD:275368	5/18 (28%)
		C2H2 Zn finger	352..373	CDD:275368	8/20 (40%)
zgc:162972	XP_021323880.1	COG5048	8..328	CDD:227381
		C2H2 Zn finger	12..32	CDD:275368
		C2H2 Zn finger	40..60	CDD:275368
		C2H2 Zn finger	68..88	CDD:275368
		C2H2 Zn finger	96..116	CDD:275368
		C2H2 Zn finger	124..144	CDD:275368
		C2H2 Zn finger	152..172	CDD:275368
		COG5048	176..603	CDD:227381	62/261 (24%)
		C2H2 Zn finger	180..200	CDD:275368
		C2H2 Zn finger	208..228	CDD:275368
		C2H2 Zn finger	236..256	CDD:275368
		C2H2 Zn finger	264..284	CDD:275368
		C2H2 Zn finger	292..312	CDD:275368
		C2H2 Zn finger	320..340	CDD:275368
		C2H2 Zn finger	391..411	CDD:275368	8/21 (38%)
		COG5048	417..799	CDD:227381	104/432 (24%)
		C2H2 Zn finger	419..439	CDD:275368	0/19 (0%)
		C2H2 Zn finger	447..467	CDD:275368	4/19 (21%)
		C2H2 Zn finger	475..495	CDD:275368	6/25 (24%)
		C2H2 Zn finger	503..523	CDD:275368	6/26 (23%)
		C2H2 Zn finger	531..551	CDD:275368	3/20 (15%)
		C2H2 Zn finger	559..579	CDD:275368	6/21 (29%)
		C2H2 Zn finger	587..607	CDD:275368	9/21 (43%)
		C2H2 Zn finger	615..635	CDD:275368	9/19 (47%)
		C2H2 Zn finger	643..663	CDD:275368	1/19 (5%)
		C2H2 Zn finger	671..691	CDD:275368	7/20 (35%)
		C2H2 Zn finger	699..719	CDD:275368	5/19 (26%)
		C2H2 Zn finger	727..747	CDD:275368	7/22 (32%)
		C2H2 Zn finger	755..775	CDD:275368	8/20 (40%)
		C2H2 Zn finger	783..803	CDD:275368	5/28 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910