DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17829 and zgc:112083

DIOPT Version :9

Sequence 1:	NP_652054.1	Gene:	CG17829 / 47718	FlyBaseID:	FBgn0025635	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001017764.1	Gene:	zgc:112083 / 550461	ZFINID:	ZDB-GENE-050417-284	Length:	504	Species:	Danio rerio

Alignment Length:	429	Identity:	138/429 - (32%)
Similarity:	220/429 - (51%)	Gaps:	15/429 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 KRKKPAELELTCGWRDCQEICTGEWSLNGHIGDHLEHYAKAQDDRGAHAEHTEHQCTWNSCDF-R 79
            ||:..:.:.:.|.|..|.........|:.|:..||:.:....|   |..|..::.|.|..|:| .
Zfish     3 KRRNASNIVVACEWASCSFKSQSMEELSDHMSLHLKEHLGEGD---AMEELEDYPCLWRGCEFLA 64

  Fly    80 TENQVEFERHSYYHGYYLNLLLQGKLECDLHPEIPACTAPARLMEKLPALGQNFRCGWTDCEREF 144
            ..:|.|...|:::|.::..|...|....:.||::|:||........:|.:.:.|.|.|..||..|
Zfish    65 MGSQSELMAHAHFHIFHSKLKYIGTQLLESHPDLPSCTQDLHNSSLVPDVSEGFVCQWQHCESSF 129

  Fly   145 VSIVEFQDHIVKHALFEYDIQKTPEDERPKTMCNWAMCHKHMGNKYRLIEHISTHSNKKQVACFH 209
            .:...|..|:..||... ::|..| |.:....|:|:.|......||||.||:.:|:.::.|||..
Zfish   130 NNPEWFYRHVDMHAHCT-ELQPLP-DRQQALFCSWSGCDAFFKIKYRLREHLRSHTQERLVACPT 192

  Fly   210 CGELFRTKTTLFDHLRRQPENNTNSFQCAQCFKFFATKKLLKSHVVRHVNCYKCTMCDMTCSSAS 274
            ||.:|.:.|..|||::||.|.. :|..|..|.|.||.::||:.||.:|||..||.:|||||:|.|
Zfish   193 CGCMFSSNTKFFDHIQRQAEPE-DSLTCGHCDKAFANERLLRDHVRQHVNHIKCPLCDMTCTSLS 256

  Fly   275 SLTTHIRYRHLKDKPLKCSECDTRCVRESDLAKHVQIVHSKTVHQCEHPDCHYSVRTYTQMRRHF 339
            :|..||::||..::|..|..|::....:.||.:|::..:....:.|....|.||.|....|.:|:
Zfish   257 TLKIHIKFRHCDERPFPCDFCESSFKNQHDLRRHMETHNEGAAYHCTVEGCGYSSRMAHTMNQHY 321

  Fly   340 LEVHGNNPI-LYACHCCERFFKSGKSLSAHLMKKHGFRLPSGHKRFTYRVDENGFYRLETTRLES 403
            ...|.:|.: .|.||.|::.|....:|:.||.|||..:.||||.||.|:.||:|:.||...|.|:
Zfish   322 KRAHEDNMVPQYKCHLCDKTFSWCYTLTLHLRKKHQLKWPSGHSRFRYKKDEDGYLRLNMVRFET 386

  Fly   404 LEVTQQILSPQVNDSLAKPGTGSCYEIVDPTNTEFERII 442
            :|||::::.........:..:.       |||...|.::
Zfish   387 VEVTEELIKNMAEKRTPRKTSA-------PTNHSKEPLL 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	7/16 (44%)
		C2H2 Zn finger	207..225	CDD:275368	8/17 (47%)
		C2H2 Zn finger	237..257	CDD:275368	9/19 (47%)
		C2H2 Zn finger	263..284	CDD:275368	11/20 (55%)
		C2H2 Zn finger	292..311	CDD:275368	5/18 (28%)
		C2H2 Zn finger	352..373	CDD:275368	8/20 (40%)
zgc:112083	NP_001017764.1	C2H2 Zn finger	163..182	CDD:275368	7/18 (39%)
		C2H2 Zn finger	190..211	CDD:275368	9/20 (45%)
		C2H2 Zn finger	219..239	CDD:275368	9/19 (47%)
		COG5236	<234..>356	CDD:227561	43/121 (36%)
		C2H2 Zn finger	245..266	CDD:275368	11/20 (55%)
		C2H2 Zn finger	274..294	CDD:275368	5/19 (26%)
		C2H2 Zn finger	302..320	CDD:275370	6/17 (35%)
		C2H2 Zn finger	335..353	CDD:275368	6/17 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	119	1.000	Domainoid score	I5758
eggNOG	1	0.900	-	-		E1_KOG3608
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	299	1.000	Inparanoid score	I2682
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D564393at33208
OrthoFinder	1	1.000	-	-		FOG0005624
OrthoInspector	1	1.000	-	-		otm25258
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24391
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5014
SonicParanoid	1	1.000	-	-		X96
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	11.000