DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17829 and znf420

DIOPT Version :9

Sequence 1:	NP_652054.1	Gene:	CG17829 / 47718	FlyBaseID:	FBgn0025635	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001016394.1	Gene:	znf420 / 549148	XenbaseID:	XB-GENE-5724906	Length:	410	Species:	Xenopus tropicalis

Alignment Length:	293	Identity:	78/293 - (26%)
Similarity:	111/293 - (37%)	Gaps:	60/293 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 ACTAPARLMEKLPALGQN---------FRCGWTDCEREFVSIVEFQDHIVKHALFEYDIQKTPED 170
            :||...:...:..:|.::         |.|  |||.:.|..    ..|:|.|       |:....
Frog   129 SCTVCGKRFTQSSSLARHLRVHSEVKPFMC--TDCGKSFSQ----NSHLVTH-------QRIHTG 180

  Fly   171 ERPKTMCNWAMCHKHMGNKYRLIEHISTHSNKKQVACFHCGELFRTKTTLFDHLRRQPENNTNSF 235
            |||.: ||  .|.|.......|::|...|:.:|...|..||:.|...:.|..|||  ...|...:
Frog   181 ERPYS-CN--ECGKSFSGSSNLVKHKKVHAGEKSWHCPGCGKSFTCSSQLRTHLR--VHTNEKPY 240

  Fly   236 QCAQCFKFFATKKLLKSHVVRHV--NCYKCTMCDMTCSSASSLTTHIRYRHLKDKPLKCSECDTR 298
            .|..|.|.|::...|.:|...|.  ..|.||.|....:.:|||..|.|. |..:|...||:|...
Frog   241 ACEICGKCFSSSSNLVTHQRVHTGERPYSCTECGKRFTQSSSLVVHWRV-HTVEKLFTCSDCGKS 304

  Fly   299 CVRESDLAKHVQ----------------------IVHSKTVHQCEHP----DCHYSVRTYTQMRR 337
            ....|.|.||.:                      :|..:.||..|.|    :|....:..:.:.|
Frog   305 FSHNSLLIKHQKTHTEERPYVCMECGKGFTGSSALVRHQRVHTEERPYTCSECGKRFKDKSSLVR 369

  Fly   338 HFLEVHG-NNPILYACHCCERFFKSGKSLSAHL 369
            | ..||. :.|  |||..|...|..|.:|..||
Frog   370 H-SRVHSEDKP--YACASCGETFNDGSNLLEHL 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	4/16 (25%)
		C2H2 Zn finger	207..225	CDD:275368	6/17 (35%)
		C2H2 Zn finger	237..257	CDD:275368	6/19 (32%)
		C2H2 Zn finger	263..284	CDD:275368	8/20 (40%)
		C2H2 Zn finger	292..311	CDD:275368	7/40 (18%)
		C2H2 Zn finger	352..373	CDD:275368	7/18 (39%)
znf420	NP_001016394.1	CobT	<8..>91	CDD:130712
		C2H2 Zn finger	102..122	CDD:275368
		zf-H2C2_2	118..139	CDD:372612	2/9 (22%)
		C2H2 Zn finger	130..150	CDD:275368	3/19 (16%)
		COG5048	<141..386	CDD:227381	70/266 (26%)
		C2H2 Zn finger	158..178	CDD:275368	9/32 (28%)
		C2H2 Zn finger	186..206	CDD:275368	6/21 (29%)
		C2H2 Zn finger	214..234	CDD:275368	8/21 (38%)
		C2H2 Zn finger	242..262	CDD:275368	6/19 (32%)
		C2H2 Zn finger	270..290	CDD:275368	8/20 (40%)
		C2H2 Zn finger	298..318	CDD:275368	7/19 (37%)
		C2H2 Zn finger	326..346	CDD:275368	1/19 (5%)
		C2H2 Zn finger	354..374	CDD:275368	3/20 (15%)
		C2H2 Zn finger	382..402	CDD:275368	7/18 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910